Contradictory interests: Work, parents, and offspring in early modern Holland

The consistory notes of the Dutch Reformed Church (1573–1700) reveal conflicts over work between parents and children during the early modern period. Two issues that caused particular tension were the labor experience of future sons-in-law and the division of household tasks. Parents' concerns about the financial position of their future son-in-law were sincere and realistic. Skills definitely bettered the new family's chances to survive financially. Children were not expected to take care of their destitute parents nor were parents obliged to support their poverty-stricken married children. Power struggles between children and stepparents also resulted in conflicts over work. After a widowed parent remarried, children and stepparents had to redefine their roles in the new situation. The child who had assumed responsibilities when a parent died resisted a stepparent who took over those tasks. Although the cases presented may not represent everyday interactions between parents and children, they do provide insights into how work caused problems between parents and older children.     

Natural Settings Trials — Improving the Introduction of Clinical Genetic Tests

Approaches to genetic testing differ in the research setting and the clinical setting. More data are needed to develop approaches that will best facilitate the use of new genetic tests in the clinical setting, especially settings where genetic testing has not been widely used, such as in primary care. Furthermore, data are needed to establish the clinical utility of new genetic tests in the general practice setting. Natural setting trials are proposed as a strategy to develop this information. While natural setting trials are clinical research studies and will expose participants to some degree of risk, the risks are different, and arguably less than the risks those same individuals would otherwise face if the test went directly into clinical practice. Ultimately, clinical practice and safety of new genetic tests can be improved by adding the evaluation provided by natural setting trials.     

Book Reviews

Books reviewed:
The Law of Energy for Sustainable Development , edited by Adrian J. Bradbrook, Rosemary Lyster, Richard Ottinger and Wang Xi , published by Cambridge University Press, 2005, 630pp, £75.00, hardback.
Fresh Water and International Economic Law , edited by Edith Brown Weiss, Laurence Boisson de Chazournes and Nathalie Bernasconi-Osterwalder , published by Oxford University Press, 2005, 506pp, £70.00, hardback.
Handbook of Global Environmental Politics , edited by Peter Dauvergne , published by Edward Elgar, 2005, 560pp, £125.00, hardback.
Emerging Forces in Environmental Governance , edited by Norichika Kanie and Peter M. Haas , published by United Nations University Press, 2004, 320pp, US$36.00, paperback.
Economic Globalization and Compliance with International Environmental Agreements edited by Alexandre Kiss, Dinah Shelton and Kanami Ishibashi , published by Kluwer Law International, 2003, 352pp, £85.00, hardback.
German Environmental Law for Practitioners , edited by Horst Schlemminger and Claus-Peter Martens , 2nd edition, published by Kluwer Law International, 2004, 833pp, £119.25, hardback.
The International Climate Change Regime: A Guide to Rules, Institutions and Procedures , Farhana Yamin and Joanna Depledge , published by Cambridge University Press, 2004, 730pp, £40.00, paperback.     

Poisoning caused by a paint stripping agents containing dichloromethane]

It is widely known that inhalation of the solvent dichloromethane can lead to severe intoxication. We report on a fatal accident of a 29-year-old painter. He had to remove the old chlorocaoutchoucpaint of two overflow pools adjoining an empty swimming pool by sand-blasting. After obviously having finished his work in the first pool the painter was found dead, lying on the floor of the second pool. Later an almost empty 10-kg-canister of a paint stripper (macerating agent) the main component of which was dichloromethane was found in the car of the painter. Blood samples of the corpse measured by head space gas chromatography and electron capture detection showed dichloromethane levels in the range of 513-773 micrograms/ml.     

The zinc test as an alternative for acid phosphatase spot tests in the primary identification of seminal traces

The value of the acid phosphatase spot test in the primary visualization and identification of seminal traces is hampered by the sensitiveness of the enzyme to biodegradation. An alternative spot test is proposed, based on the high concentration of the more stable zinc metal in seminal plasma. The proposed zinc spot test is simple and suitable for on site investigation. Although the sensitivity in fresh stains is lower than that of the acid phosphatase spot test, this is largely compensated by the lower sensitiveness to biodegradation. The specificity for semen is higher than that of the acid phosphatase spot test. In vaginal swabs it was nevertheless seen, that samples should be taken within 24 h after alleged sexual assault to give reliable results.