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The specificity of antisera raised against each of the prostaglandin series 190H E1/E2 and 190H F1 alpha/F2 alpha, produced in males, was evaluated by radioimmunoassay. Further, the ability of these antisera to detect semen specific prostaglandins in mixtures of body fluids was examined. Antisera directed against the 190H E1/E2 series cross-reacted with prostaglandin E1 and marginally with E2. Antisera raised to the 190H F1 alpha/F2 alpha series were, however, highly specific to the semen specific prostaglandins 190H F1 alpha/F2 alpha and 190H E1/E2. It was possible to detect picogramme quantities of contaminating 190H F1 alpha/F2 alpha on vaginal swabs taken up to 72 h after intercourse and on vaginal swabs stored at room temperature for up to 2 years. These prostaglandins were not detected on semen free vaginal swabs, in faecal material, saliva, urine or in a sample of human milk (stain). A limited study of casework material is also described. Detection of the 190H F series, as a group, has considerable potential in the identification of human semen at picogramme levels, eliminating the need for alternative chemical tests and extensive microscopic examination.  相似文献   
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Purpose

To examine differences between members of protective service occupations (PSOs) and other occupational groups on indicators of alcohol use/abuse and mental health.

Methods

A subset of 25,622 observations from the 2009 National Survey of Drug Use and Health (NSDUH) are used to evaluate whether PSO members exhibit a higher likelihood of problematic drinking behaviors and if so, whether these behaviors are mediated by mental health problems.

Results

Logistic regression models indicated that PSO members do not consume alcohol more frequently nor do they exhibit higher likelihood of alcohol abuse/dependency when compared to members of other occupational groups. However, PSO members report higher occurrence of binge drinking. The relationship between PSOs and binge drinking behaviors is mediated by gender, not mental health problems.

Conclusion

The results provide direction for the development of evidence-based alcohol related intervention programs that address the specific needs of police officers and other public servants.  相似文献   
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This study examined the relationship between the characteristics of childhood sexual abuse (CSA) and the severity of consequent posttraumatic stress disorder (PTSD), depression, suicidal ideation, and substance use in a sample of 83 female adolescents aged 13–18 years seeking treatment for PTSD. Nearly two-thirds of the sample (60.7 %, n?=?51) reported the perpetrator of the CSA was a relative. A large portion (40.5 %, n?=?34) of the sample reported being victimized once, while almost a quarter of the sample reported chronic victimization (23.8 %, n?=?20). PTSD and depression scores were in the clinical range, whereas reported levels of suicidal ideation and substance use were low. The frequency of victimizations was associated with suicidal ideation. Contrary to expectation, CSA characteristics including trauma type, perpetrator relationship, and duration of abuse were unrelated to PTSD severity, depressive symptoms, or substance abuse.  相似文献   
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The importance of social media for election campaigning has received a lot of attention recently. Using data from the 2011 New Zealand general election and the size of candidates’ social media networks on Facebook and Twitter, we investigate whether social media is associated with election votes and probability of election success. Overall, our results suggest that there is a statistically significant relationship between the size of online social networks and election voting and election results. However, the size of the effect is small and it appears that social media presence is therefore only predictive in closely contested elections.  相似文献   
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