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In comparison to the general adolescent population, adolescents with a history of externalizing behaviors including substance use and conduct disorder are younger at first intercourse, have a larger number of sexual partners, and use condoms less often when they engage in intercourse, placing them at higher risk for sexually transmitted diseases as well as unplanned pregnancy (Morris, R. E., Baker, C. J., Valentine, M., and Pennisi, A. J. (1998). J. Adolesc. Health 23: 39–48). A primary goal of this paper was to examine linkages between Cloninger's novelty-seeking, harm avoidance, and reward dependence dimensions and risky sexual behavior among 200 boys in treatment for substance abuse and delinquency compared to 200 boys recruited from the community, and matched on age, ethnicity, and geographic location. Analyses indicated that though there were mean differences on all personality constructs examined, these differences in personality failed to account for observed differences in risky sexual behavior. The structure of problem behavior also differed in the 2 groups.  相似文献   
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The ability of bile to concentrate drugs and metabolites coupled with its general availability make it suitable for analysis and often the fluid of choice in postmorten cases requiring drug screening. Bile (5 to 10 ml) was diluted with water, sulfuric acid was added, and the mixture was autoclaved. The precipitated bile salts were easily removed by filtration and the filtrate (pH adjusted to 8.0 to 8.5) extracted with XAD-2 resin. Drugs were eluted with a mixture of ethyl acetate/1,2-dichloroethane and analyzed with thin-layer chromatography. Varying the dilution of bile improved the recovery of morphine, codeine, methadone, amobarbital, and phenobarbital. Excessive dilution, however, caused a washing phenomenon and reduced recovery of some drugs, as shown with morphine and codeine. The procedure described is useful for the rapid screening of bile specimens for drugs.  相似文献   
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The modern social citizen is a dual figure: at one and the same time a legal-universal abstraction and a particular living being with specific capacities, proclivities and attitudes. The Settlement movement from the late nineteenth century articulated and shaped both universal and particular dimensions of social citizenship. It contained the imperative of guidance of individual conscience and the modern discourse of universal social rights. The article demonstrates that it is impossible to maintain a division between, on one side, the subject of individualizing pastoral care originating in religious poor relief and philanthropy, and, on the other side, formal rights based on universalism and the modern state. The Settlement movement lies at the pathway of belief, subjective interpretation and respect for the particular person and at the pathway of factual knowledge of social patterns and large-scale policy reforms. The focus on the particular person as subject was the legacy of Christian piety, whereas the concept of universal citizen was associated with the rise of social science at the University of Chicago. We explore this paradox of the particular and the universal through the work of Jane Addams as both sociologist and founder of Hull House.  相似文献   
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