Detection of drugs using XAD-2 resin. I:Choice of resin, chromatographic conditions, and recovery studies

Amberlite XAD-2, a nonionic polystyrene divinylbenzene resin, was first used for the analysis of drugs in urine and a number of reports have described the development at optimal conditions for extraction, including type of resin columns, pH conditions, and eluting solvents. XAD-4 and XAD-7 resins were compared to the similarly structured XAD-2 resin and no significant advantage over the XAD-2 resin for drug screening was observed. A quantity of 5 to 6 g of resin was found to have sufficient capacity for the extraction of 200 ml of pentobarbital solution (1 mg/100ml). A column flow rate of approximately 15 ml/min (gravitational flow) was sufficient for analysis and slower rates were not more efficient. A mixture of ethyl acetate and 1,2-dichloroethane (3:2) was found to give best overall recovery (66 to 94%) of drugs, the resulting extracts being reasonably free of interfering substances. A pH value of 8.5 is recommended as optimum for comprehensive analysis of acidic and basic drugs. Recovery studies were conducted on spiked samples to determine drug losses occuring during various steps in the XAD-2 extraction procedure for four acidic (amobarbital, secobarbital, pentobarbital, and phenobarbital) and four basic (morphine, codeine, meperidine, and methadone) drugs. A relatively small amount (0 to 5%) of the drugs was not adsorbed by the resin and amounts varying from 6 to 40% failed to be desorbed by the eluting solvent. Additional losses occurred during the removal and analysis of TLC spots. Recovery of drugs from aqueous solutions analyzed with the XAD-2 resin were compared to recoveries reported in the literature with other XAD-2 resin methods for the extraction of drugs from urine. Recovery of phenobarbital, morphine, and codeine improved by 4 to 23% while recoveries of amobarbital, pentobarbital, secobarbital, methadone, and meperidine were 4 to 28% less efficient when compared to literature data.     

Social Networks and the Affective Impact of Political Disagreement

Although few studies have explored the link between emotion and political talk, here I argue that political disagreement depolarizes emotional reactions via information exchanged in social networks. Analyzing data from the ANES 2008–2009 Panel Study, several conclusions are drawn. First, disagreement increases negative emotions and decreases positive emotions toward the in-party candidate, and also increases positive emotions and decreases negative emotions toward the out-party candidate. In other words, disagreement depolarizes emotions toward political candidates. Second, the affective impact of disagreement does not vary with political knowledge. Finally, positive emotions toward the out-party candidate and negative emotions toward the in-party candidate reduce political interest, candidate issue placement accuracy, and political participation. Overall, this study develops important theoretical connections between affect and political talk that have implications for the value of political disagreement.     

War crimes prosecutors and intelligence agencies: the case for assessing their collaboration

Whilst recognizing important distinctions between different types of intelligence agency, and a range of possible contradictions between the imperatives governing the two types of agency, it is necessary to overcome the one-side quality of much existing literature, whose critique of the subversion of the rule of law by intelligence agencies tends to preclude any appreciation that such agencies can play a supportive role for war crimes prosecutors. This article challenges the assumption that analysis of the histories of Western intelligence agencies and the study of war crimes trials must be studied as entirely separate and sharply demarcated fields of inquiry; it advocates an interdisciplinary research programme, informed by a series of indepth historical case studies, capable of addressing issues arising from the interaction between these two institutional fields. The proposed research agenda could illuminate aspects of the contemporary role – and future potential of both intelligence agencies and war crimes prosecution bodies. It would investigate tensions between the prosecutors need to employ intelligence agencies to gather trial credible evidence and detain indicted defendants, often by covert and legally questionable means, and the constitutional justifications for holding war crimes trials by reference to the need to reassert the rule of law in the wake of lawless genocide.     

Financial derivatives and the theory of money

Abstract

Financial derivatives are used and counted as money, but it is unclear exactly what sort of money they are. This article explores the monetary role of financial derivatives in securing the global financial system. It finds that derivatives commensurate the values of different forms of financial assets, and, in the process, they facilitate continuity across different forms of money. In this role they are a form of commodity money, but very different from conventional understandings of commodity money. In developing this idea, the paper engages recent debates in Economy and Society about the nature of money. In particular, it takes issue with Ingham's state theory of money, which cannot adequately engage exchange rate volatility and extra-national roles of money, and Lapavitsas’ approach to a Marxist theory of money, which relegates commodity money to a historical abstraction.     

Fundamental value: a category in transformation

Abstract

‘Fundamental value’ is a canonical category in both Marxian and neo-classical economics. In application to finance and financial crisis, it is laden with complexity. For Marxists, it has underscored a focus on the distinctions between production and circulation, real and fictitious capital. These debates have dominated Marxian responses to the financial crisis. In mainstream finance and economics, the term has undergone transformation and historically driven adaptation. Marxian analysis could fruitfully follow this lead. This paper identifies that transformation as an expression of capital's transforming calculation project. As capital becomes more liquid, the concept of fundamental value itself must embrace liquidity, yet, in embracing liquidity, fundamental value loses its established definitive capacity.     

Relationship of School Context to Rural Youth’s Educational Achievement and Aspirations

Though the poverty encountered by many rural youth encompasses numerous developmental challenges and substantially increases the chances for educational problems, the school context is central to promoting and constraining their development. Therefore, the purpose of this study was to investigate the relationship of school characteristics and schooling experiences to the educational achievement and aspirations of youth from high-poverty rural communities. Differences in the relationship of school characteristics and schooling experiences to the educational outcomes of students from high- versus low-poverty rural communities were also examined. Participants included 6,247 high school students from 43 low-poverty and 21 high-poverty rural communities. Approximately 51.7% of participants were female and the sample was racially/ethnically diverse (66.4% White, 9.2% African American, 8.1% Hispanic/Latino(a), 4.4% Native American, and 11.8% Multiracial). After controlling for student and family background, school characteristics (e.g., lower student–teacher ratio) were predictive of achievement for rural youth from high-poverty communities. Schooling experiences (e.g., positive perceptions of their ability, a sense of school valuing and belonging, and preparation for postsecondary education) were predictive of educational achievement and aspirations for rural youth from high- and low-poverty communities. Overall, the study highlights unique ways schools can positively shape the educational outcomes for rural youth despite community poverty.     

Judith N. Shklar and American citizenship

It is claimed that although the European debate about social rights has concentrated on the formation of citizenship, American political and social theory has focused almost exclusively on civil liberties and individual rights. The specific characteristics of American history – the Declaration of Independence, slavery, the Civil War, the persistence of the race issue and the civil rights movement – explain this fundamental difference. This article explores some of the exceptions to this claim in the work of sociologists and political scientists such as W.E. DuBois, Talcott Parsons, Morris Janowitz, Rogers Smith and Michael Schudson, but the contrast between individual rights and social rights remains important. The American tradition is explored primarily through the work of Judith N. Shklar whose approach to cruelty, misfortune and inequality represented a major and innovative approach to what we might call the phenomenological foundation of justice and rights. She emphasised the importance of earning a living to the basic American understanding of dignity and responsibility. The article concludes by speculating that the credit crunch and more importantly the endemic character of unemployment and under-employment in the modern economy radically undermine access to rewarding employment for the majority of the population. These economic and social changes – ‘the financialization of capitalism’ – make the defence of social citizenship more rather than less important.     

Positive versus normative economics: what’s?the?connection? Evidence from the Survey of?Americans and?Economists on the Economy and?the?General?Social?Survey

Previous research suggests that positive and normative beliefs about economics are largely unrelated. Using questions from two national surveys, this study finds that: (a)?the underlying determinants of positive and normative beliefs are strikingly similar; (b)?education is by far the strongest overall determinant of both positive and normative beliefs; and (c) the variables known to push positive beliefs in the same direction as formal economic training—education, male gender, income growth, and job security—also push normative beliefs in the same direction. These results strongly suggest that the positive-normative connection has been underestimated.