Cyanide quantification in post-mortem biological matrices by headspace GC-MS

Cyanide is a powerful chemical asphyxiant found in some forensic cases following voluntary (suicide) or involuntary ingestion (fire, accidental exposure). A quantification method for cyanide that is specifically suited to post-mortem forensic purposes was developed. Determination was performed by headspace gas chromatography coupled to mass spectrometry using a GS-GASPRO column on an HP-6890 gas chromatograph with an HP-5973N mass detector. The biological sample was treated with an internal standard, frozen, glacial acetic acid was added and the sample was then incubated at 60°C for 15min. The headspace was sampled with a disposable syringe, and analyzed to quantify hydrogen cyanide. Isotopically labeled cyanide ((13)C(15)N) was used as the internal standard to minimize matrix effect and sampling error. The method produced an extended linear dynamic range (0.07-50μg/mL), and a method detection limit of 0.02μg/mL. Identical calibration curves were obtained when blood, gastric contents and aqueous solutions were used as the calibration standard matrix. This method was also successful in quantitating cyanide in gastric contents, one of the most variable biological fluids. The method has been validated and is being used for current forensic cases such as fire victims and suicides.     

Religious perspectives on umbilical cord blood banking

Umbilical cord blood is a valuable source of haematopoietic stem cells. There is little information about whether religious affiliations have any bearing on attitudes to and decisions about its collection, donation and storage. The authors provided information about umbilical cord blood banking to expert commentators from six major world religions (Catholicism, Anglicanism, Islam, Judaism, Hinduism and Buddhism) and asked them to address a specific set of questions in a commentary. The commentaries suggest there is considerable support for umbilical cord blood banking in these religions. Four commentaries provide moral grounds for favouring public donation over private storage. None attach any particular religious significance to the umbilical cord or to the blood within it, nor place restrictions on the ethnicity or religion of donors and recipients. Views on ownership of umbilical cord blood vary. The authors offer a series of general points for those who seek a better understanding of religious perspectives on umbilical cord blood banking.     

“Mitigating Instigation”: Cultural Phenomenological Influences of Anger and Fighting Among “Big-Boned” and “Baby-Faced” African American Youth

While the violent behavior of youth continues to strike fear in the hearts of American citizens, researchers still are unable to make sense of interpersonal and ecological cultural factors that mitigate anger acted out toward others and turned inward. A cultural phenomenological perspective was applied to investigate if self- and other-perceived physical maturity and racial socialization experiences were influential in the expressions of anger and aggression among African American youth. Cross-validation of self-reports of fighting variables was found. Results indicate that the initiation and frequency of fighting behavior is higher for boys, youth who look physically mature, who report lower levels of calamity fear, lower levels of racial socialization, higher levels of anger acting out, and lower levels of anger control. Racial socialization is proposed as 1 way to manage cultural ecological demands that may lead to the use of aggression. Implications for community psychological intervention of violence are proposed.     

Accidental Trauma Mimicking Homicidal Violence

Homicide investigations represent an important function of death investigators. Although recognizing nonobvious homicides is crucial, an equally important role involves the identification of cases that initially present as possible homicides, but are ultimately discovered to not represent homicides. Failure to recognize such cases results in wasted time, squandered resources, false allegations, and potential life‐altering consequences. The authors review a series of cases wherein initial investigation suggested a possibility that the deaths represented homicides. By carefully considering additional information, including scene findings, history, and postmortem examination, each was determined to represent an accidental traumatic death. In addition to highlighting the importance of recognizing accidental traumatic deaths that initially present as homicides, the cases serve to highlight the fact that forensic pathology cannot be practiced without knowledge of appropriate ancillary information. Although guarding against cognitive bias is important in all forensic disciplines, including forensic pathology, access to vital case‐related ancillary information is an essential component of practicing medicine as a forensic pathologist.     

The relationship between mental illness and violence in a mentally disordered offender sample: evaluating criminogenic and psychopathological predictors

The importance of mental illness as a risk factor for violence has been debated with significant implications for mental health policy and clinical practice. In offender samples, psychopathology tends to be unrelated to recidivism, although some researchers have noted that this relationship may be dependent upon certain moderating factors. In the present, prospective investigation, psychopathology is examined as predictors of recidivism in 121 provincially sentenced (i.e. less than 2 years) mentally disordered offenders. Results indicated that psychopathological predictors were generally poor predictors of recidivism in univariate and multivariate analyses. Consistent with our hypotheses, age of onset of criminal activity was a significant moderating factor on the relationship between mental illness and recidivism, although results were not in the expected direction for certain classes of mental illness. Results are discussed in the context of a social learning model of crime and in terms of the treatment of mentally disordered offenders.     

Compensation System Experience at 12 Months After Road or Workplace Injury in Victoria,Australia

Seeking or receiving compensation after injury is frequently associated with poor recovery. Previous research has shown that the stressful nature of compensation procedures and perceived injustice may cause secondary harm. This study examined compensation system experiences in compensation claimants in Victoria, Australia, and explored the relationship between these experiences and injury outcomes. One hundred and sixty compensable patients (120 male, 75.0 %) aged 18–67 years (M?=?43.01, SD?=?14.31), hospitalized for an injury in a motor vehicle crash (n?=?137) or at work (n?=?23), participated. Participants completed questionnaires about compensation system experience, pain, and psychological symptoms 12 months after injury. Principal component analysis (PCA) of the compensation system experience items revealed three components explaining 66.64 % of the variance in compensation experience: (1) “negative procedural experience” (47.29 %), (2) “compensation supported recovery” (10.43 %), and (3) “positive procedural experience” (8.92 %). Worse experience on all components was associated with worse pain (severity, interference, catastrophizing, disability) and psychological symptoms (anxiety, depression, PTSD, perceived injustice). Compensation system experience reflected both negative and positive procedural factors, and feeling supported through recovery. Most participants reported having positive experiences; however, those who were frustrated or stressed from compensation procedures had worse pain and psychological health outcomes. While this association is likely to be bidirectional with “non-recovery” also impacting on compensation experience appraisals, compensation schemes should nonetheless address modifiable sources of procedural injustice (e.g., arduous paperwork and approvals processes) and reinforce procedures that generate perceptions of support (e.g., timely and appropriate access to health services).