A fast preparation of skeletal materials using enzyme maceration

The current study investigates the removal of soft tissues from mice and rats by the use of three different proteases and one lipase from Novozymes A/S. The results demonstrate the enzyme maceration to be remarkably fast (1-3 h) compared to the traditional warm-water procedure, which requires up to several days. In addition, the enzyme maceration eliminates the odor problem associated with the traditional procedure. It is shown that stirring of the enzyme maceration bath is the main factor which determines the speed of the maceration. For mice, the time required for enzyme maceration can vary from 1 to 8 h depending on the stirring speed. The method investigated here allows preparation of skeletal material in an essentially odorless way within a matter of hours, making the method useful in particular for forensic science, private conservation workshops, and educational purposes.     

Intergenerational continuities and discontinuities in intimate partner violence: a two-generational prospective study

This study focuses on intergenerational continuity in violent partner relationships. We investigate whether exposure to caregiver intimate partner violence (IPV) during adolescence leads to increased involvement in IPV during early adulthood (age 21-23) and adulthood (age 29-31). We also investigate whether this relationship differs by gender. Although there is theoretical and empirical support for intergenerational continuity of relationship violence, there are few prospective studies of this issue. We use data from the Rochester Youth Development Study (RYDS), a longitudinal study of the development of antisocial behavior in a community sample of 1,000 urban youth followed from age 14 to adulthood. The original sample includes 73% men and 85% African American or Hispanic youth. Measures come from a combination of interviews and official records. The Conflict Tactics Scale (CTS) is used to assess IPV and severe IPV in the youth and parent generations. Analyses controlled for child physical abuse, race/ethnicity as well as parent education, family stability, and poverty. In multivariate models, adolescent exposure to caregiver severe IPV resulted in significantly increased risk of relationship violence in early adulthood (age 21-23). Furthermore, there is an indirect effect of adolescent exposure to severe IPV on later adult involvement in IPV (age 29-31), mediated by involvement in a violent relationship in early adulthood. These results were largely invariant by gender. However, we observed a direct pathway between IPV exposure and adult IPV for women (marginally significant) suggesting that adolescent exposure to caregiver IPV may set in motion women-specific processes.     

How Credible Is the Evidence,and Does It Matter? An Analysis of the Program Assessment Rating Tool

This research empirically assesses the quality of evidence that agencies provided to the Office of Management and Budget in the application of the Program Assessment Rating Tool (PART), introduced in 2002 to more rigorously, systematically, and transparently assess public program effectiveness and hold agencies accountable for results by tying them to the executive budget formulation process and program funding. Evidence submitted by 95 programs administered by the U.S. Department of Health and Human Services for the PART assessment is analyzed using measures that capture the quality of evidence and methods used by programs and information on characteristics of agencies that might relate to program results and government funding decisions. The study finds that of those programs offering some evidence, most was internal and qualitative, and about half did not assess how their performance compared to other government or private programs with similar objectives. Programs were least likely to provide externally generated evidence of their performance relative to long‐term and annual performance goals. Importantly, overall PART and results scores were (statistically) significantly lower for programs that failed to provide quantitative evidence and did not use long‐term measures, baseline measures or targets, or independent evaluations. Although the PART program results ratings and overall PART scores had no discernible consequences for program funding over time, the PART assessments appeared to take seriously the evaluation of evidence quality, a positive step forward in recent efforts to base policy decisions on more rigorous evidence.     

Biology,Ideology, and Epistemology: How Do We Know Political Attitudes Are Inherited and Why Should We Care?

Evidence that political attitudes and behavior are in part biologically and even genetically instantiated is much discussed in political science of late. Yet the classic twin design, a primary source of evidence on this matter, has been criticized for being biased toward finding genetic influence. In this article, we employ a new data source to test empirically the alternative, exclusively environmental, explanations for ideological similarities between twins. We find little support for these explanations and argue that even if we treat them as wholly correct, they provide reasons for political science to pay more rather than less attention to the biological basis of attitudes and behaviors. Our analysis suggests that the mainstream socialization paradigm for explaining attitudes and behaviors is not necessarily incorrect but is substantively incomplete.     

The protective role of coping and social resources for depressive symptoms among young adolescents

Early adolescence is a period of the life course involving high levels of challenge that are stressful for some, perhaps resulting in depressive symptoms. In this study, adolescents were divided into four groups based on indices of depression and negative life events. Group differences in coping style, mastery, optimism, and social resources as well as group differences in patterns of change were investigated. Participants were 458 adolescents in sixth and seventh grade from a rural working class community. Subjects were assessed twice over a one-year period. Analyses revealed that the four groups were characterized by different levels of coping and social resources. Asymptomatic youth reported higher levels of optimism, mastery, active coping, and more positive relationships with parents and peers than did symptomatic adolescents. These same characteristics distinguished the resilient adolescents from the vulnerable adolescents, suggesting potential stress-buffering effects. One year later, the adolescents who were low on both depressive symptoms and negative life events continued to report more individual and contextual resources than the adolescents in the other groups.This research was supported by a grant from the William T. Grant Foundation (8912789) to Anne C. Petersen, Principal Investigator. The writing of this article was supported by The National Institute of Mental Health Research Training Grant 5 T32 MH18387-06 in Child Mental Health/Primary Prevention.Received Ph.D. from the Department of Human Development and Family Studies at Pennsylvania State University, and did a postdoctoral fellowship in prevention research at Arizona State University. Research interests include adolescent development, prevention, and community psychology.(on leave to the National Science Foundation). Received Ph.D. from the University of Chicago. Research interests include biopsychosocial development at adolescence, adolescent depression and interventions to prevent it, gender issues, and developmental methodology.     

A self-image questionnaire for young adolescents (SIQYA): Reliability and validity studies

This article describes a questionnaire measure of self-image designed for young adolescents. It represents a downward extension of the Offer Self-Image Questionnaire and utilizes nine scales from that instrument: Emotional Tone, Impulse Control, Body Image, Peer Relationships, Family Relationships, Mastery and Coping, Vocational/Educational Goals, Psychopathology, and Superior Adjustment. This 98-item questionnaire elicits responses on a 6-point Likert-type scale. The alpha coefficients for each scale are high, indicating a high degree of internal consistency among the items. The validity of this instrument is examined through factor analyses and through the association of these scales with other measures of self-image. The results suggest that this questionnaire provides a useful way to assess self-image among young adolescents.This research was supported by Grant MH 30252/38142 to Anne Petersen.Received Ph.D. from the University of Chicago in 1973. Research interest is biopsychosocial development in adolescence, with a focus on sex differences.Research interests are vocational development and contextual influences on development in early adolescence.Research interests are the influences of adolescent and parent development on family relationships.Received M.D. from the University of Chicago. Research interests are the psychology and psychopathology of adolescents.Current research interests are social cognition and peer relationships during early adolescence.     

The Relationship Between Traumatization and Pain: What is the Role of Emotion?

The role of emotion in the relationship between traumatic experiences and physical pain was examined via path modeling by using a sample of hospital outpatients (N = 138). Most of the participants reported being traumatized (77%) and experiencing chronic pain (69%). Trauma survivors and nontraumatized individuals did not differ significantly on mean symptom scale scores (i.e., depression, anxiety, anger, dissociation, somatization and pain). However, a moderate effect size was found for dissociation. There were also significant associations found between trauma levels and levels of adult symptomatology. Interestingly, sexual abuse was less highly correlated with symptomatology than other types of traumatization, such as neglect. None of the three proposed path models describing the relationship between trauma, pain, and emotion fit the data successfully. Implications are discussed.