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921.
Dorothy E Roberts 《The Journal of law, medicine & ethics》2008,36(3):537-545
This article presents a preliminary framework for exploring the intersection of science and racial politics in the public debate about race-based pharmaceuticals, especially among African Americans. It examines the influence of three political approaches to race consciousness on evaluations of racial medicine and offers an alternative critique. 相似文献
922.
P.M. Vallone M.C. Kline D.L. Duewer A.E. Decker J.W. Redman J.C. Travis M.V. Smith J.M. Butler 《Forensic Science International: Genetics Supplement Series》2008,1(1):80-82
National Institute of Standards and Technology SRM 2372 human DNA quantitation standard has been produced to support the need for a human-specific DNA quantitation standard in forensic casework and calibration of new quantitative polymerase chain reaction (qPCR) assays. The conventional DNA concentration has been assigned with one of the U.S. National Reference UV/Visible Spectrophotometers, assuming an absorbance of 1.0 at 260 nm equals 50 ng/μL of double stranded DNA. In addition, an interlaboratory study has been conducted, to verify that the SRM 2372 materials perform well in currently used DNA quantitation assays by the forensic DNA community. Each unit of SRM 2372 consists of three well-characterized DNA extracts. Component A is a single-source human male material derived from blood. Component B is a multiple-source human female material derived from blood. Component C was purchased as a purified unsheared genomic human DNA (Sigma-Aldrich Co., St. Louis, MO) obtained as a lyophilized human genomic extract and has both male and female donors. SRM 2372 is intended to enable the comparison of DNA concentration measurements across time and place. Manufacturers can use SRM 2372 to validate the values assigned to their own reference materials. Individual forensic laboratories can use SRM 2372 to validate DNA quantitation methods and to verify the assigned concentration of in-house or commercial DNA calibration standards. 相似文献
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In 16 medical examiner's cases, which were found to be barbiturate-positive by thin-layer chromatographic screening of the liver, blood barbiturate concentrations were determined by gas chromatography. The corresponding vitreous humor samples were screened by the enzyme multiplied immunoassay technique, the EMIT-st serum barbiturate assay. By using the recommended dilution for detecting serum barbiturates, it was possible to detect barbiturates in vitreous humor at a toxic concentration. By using one fourth the amount of diluent, the barbiturates could be detected also at a therapeutic concentration. The EMIT-st assay proved to be useful in the screening for barbiturates in vitreous humor, a material that is readily available in forensic toxicology. 相似文献
926.
What We Have Learned About Teaching Multiparty Negotiation 总被引:1,自引:1,他引:0
Lawrence Susskind Robert Mnookin Lukasz Rozdeiczer Boyd Fuller 《Negotiation Journal》2005,21(3):395-408
This article grows out of our experience teaching an advanced course on multiparty negotiation. The main question underlying the course is: “How can experts in two‐party negotiations make themselves effective multiparty negotiators?” In this article, we describe what and how we taught, what we think worked, and what we decided to change after the first year of teaching. 相似文献
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928.
The first 150 words of the full text of this article appear below. Key points
1. Introduction
Scholarship describes professionals who participate in securitiesofferings, and who represent public companies in . . . [Full Text of this Article]
2. Background
3. Modelling law firm impact in IPOs
Theories of IPO pricing Relationship between pre-IPO price adjustment and diligence in legal services Extension of Hanley's model Conservative modelonly a portion of the impact is identified Issuer's counsel v underwriters counsel Confirming proper model specification Increased risk of an investment in the issuer affecting probability of engagement of quality law firm Different signs between issuer's lawyer and underwriters lawyer
4. Data
Summary statistics Measure of law firm prestige
- The article investigates the relationship betweenpricing in an initial public offering (IPO) and the prestigeof the participating underwriters law firm.
- The hypothesisof the article is that law firm quality affects how law firmsperform their obligations in IPOsmore prestigious lawfirms acting more independently. Consistent with this hypothesis,the authors find a negative relationship between pre-IPO priceadjustment and the participation of prestigious underwriterscounsel, and a negative relationship between the participationof prestigious underwriters counsel and initial return,which is consistent with market trading reflecting the decreasedrisk associated with offerings involving prestigious underwriterscounsel.
- Finally, it is found that certain observable characteristicsindicating diminished likelihood of undisclosed negative information(venture backing and quality of the issuer's counsel) are associatedwith an increased likelihood that prestigious underwriterscounsel is used.