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Grassin Delyle S Duverneuil-Mayer C Abe E Mathieu B Lorin De La Grandmaison G Charlier P Alvarez JC 《Forensic science international》2008,178(2-3):e19-e21
The dead body of a 44-year-old woman, previously known for depression and alcoholism, has been discovered at her place of residence by her husband. A forensic autopsy has been carried out. The results indicated unspecific histological lesions (alveolar oedema, liver steatosis and interstitial nephritis) but did not reveal any apparent cause of death. Several boxes of medicines have been found near the body, justifying a toxicological analysis. This has been performed on peripheral blood and urine samples using liquid chromatography with diode array and mass spectrometric detections, in conjunction with gas chromatography coupled with mass spectrometry. Ethanol has been found (1.24 g/L in blood, 2.63 g/L in urine and 1.33 g/kg in gastric content), as well as therapeutic concentrations of meprobamate (14.1mg/L) and low concentrations of nordazepam (0.12 mg/L) in blood. On the other hand, particularly high levels of labetalol, a widely used beta-blocker, have been found both in blood (1.7 mg/L) and urine (20.2mg/L), which led us to measure labetalol levels in available viscera samples (liver, heart, kidney, and lung) and gastric content. Measured concentrations were 14.2 microg/g, 7.8 microg/g, 5.4 microg/g, 5.2 microg/g and 31.1 microg/g, respectively. We describe here the first report of a fatal intoxication attributed to labetalol that is linked to its acute toxicity, with tissue distribution of this beta-blocker. 相似文献
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This article reviews the application of metal-containing nanoparticles and nano-structured particles to fingermark detection. This area of research is attracting significant interest as advances in nanoscience are being incorporated into the field of forensic fingermark detection. Although more research is needed before some of the techniques presented can be implemented in routine casework, nanotechnology is likely to play a major role in the future to deliver more selective and more sensitive ways to detect and enhance fingermarks. 相似文献
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Ville Vili Heikkinen M.Sc. Ivan Kassamakov Ph.D. Claude Barbeau Ph.D. Sami Lehto B.Sc. Tapani Reinikainen Ph.D. Edward Hæggström Ph.D. 《Journal of forensic sciences》2014,59(1):112-116
We present work on matching 2‐mm‐thick wires using optical 3D imaging methods. Marks on such small surfaces are difficult to match using a comparison microscope as this 2D imaging method does not provide height data about the sample surface. Moreover, these 2D microscopy images may be affected by illumination. Hence, the reference and investigated sample should be present at the same time. We employed scanning white light interferometry and confocal microscopy to provide quantitative 3D profiles for reliable comparison of samples that are unavailable for simultaneous analysis. We show that 3D profiling offers a solution by allowing illumination‐independent sample comparison. We correctly identified 74 of 80 profiles using consecutive matching striae (CMS) criteria, and we were able to match samples based on profiles measured using different 3D imaging devices. The results suggest that the used methods allow matching cutter marks on thin wires, which has been difficult previously. 相似文献
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Jean Claude Saha 《Development in Practice》2008,18(2):267-272
Traditional approaches to fighting poverty have yielded unsatisfactory results in some African countries, and have been positively damaging in others. Economic growth and social expenditure on the part of both national governments and international donors have been ineffective in some countries, while in others they have exacerbated poverty. The author considers that this is due to the absence of participatory governance. From a theoretical perspective, support for participatory governance stems from Amartya Sen's approach to understanding poverty, which conceptualises poverty as a lack of capabilities, leading to social exclusion. The lack of such governance has led to the failure of traditional approaches in the fight against poverty in sub-Saharan Africa. Finally, the author proposes a tool for assessing the quality of governance, and its application in Cameroon. 相似文献
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The present review examined the predictors of job stress in correctional officers and marked the first meta-analysis of this topic area. Twenty studies were selected for inclusion, producing 191 individual effect size estimates. Overall, the findings revealed that work attitudes (i.e., participation in decision-making, job satisfaction, commitment, and turnover intention) and specific correctional officer problems (i.e., perceived dangerousness and role difficulties) generated the strongest predictive relationships with job stress. Furthermore, both favorable (i.e., human service/rehabilitation orientation and counseling) and unfavorable (i.e., punitiveness, custody orientation, social distance, and corruption) correctional officer attitudes yielded moderate relationships with job stress, with the country of study emerging as a critical moderating variable. The weakest correlates of job stress were demographic variables and job characteristics (e.g., security level). The implications of these findings are discussed and directions for future research are provided. 相似文献