Virtopsy: postmortem minimally invasive angiography using cross section techniques--implementation and preliminary results

Postmortem investigation is increasingly supported by Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). This led to the idea to implement a noninvasive or minimally invasive autopsy technique. Therefore, a minimally invasive angiography technique becomes necessary, in order to support the vascular cross section diagnostic. Preliminary experiments investigating different contrast agents for CT and MRI and their postmortem applicability have been performed using an ex-vivo porcine coronary model. MSCT and MRI angiography was performed in the porcine model. Three human corpses were investigated using minimally invasive MSCT angiography. Via the right femoral artery a plastic tube was advanced into the aortic arch. Using a flow adjustable pump the radiopaque contrast agent meglumine-ioxithalamate was injected. Subsequent MSCT scanning provided an excellent anatomic visualization of the human arterial system including intracranial and coronary arteries. Vascular pathologies such as calcification, stenosis and injury were detected. Limitations of the introduced approach are cases of major vessel injury and cases that show an advanced stage of decay.     

Experimental tests for the validation of active numerical human models

The development of numerical human models is a topic of current interdisciplinary research. In the field of automotive safety these models can be applied for the optimization of protection systems. In forensic research human models can be used for the investigation of injury mechanisms and for the prediction and reproduction of injury patterns. However, up to now human models have been validated on the basis of PMHS tests without considering the effects of muscle activity. This paper shows two experimental volunteer test set-ups for the generation of experimental validation data. In a pendulum set-up the influence of muscle activity on the human kinematics was investigated. A drop test set-up was developed for the analysis of the effects of muscle activity on impact response characteristics of muscle tissue. Experimental results, presented in this paper, can be used for the validation and optimization of active numerical human models.     

Becoming an entrepreneurial university? A case study of knowledge exchange relationships and faculty attitudes in a medium-sized,research-oriented university

This paper seeks to contribute to the growing literature on the entrepreneurial university by mapping knowledge exchange relationships of entrepreneurial faculty in a comprehensive manner and also capturing faculty attitudes towards measures taken by the university administration to promote entrepreneurship. We report on an exploratory study of Sussex University, a medium-sized, research-oriented university, which launched technology transfer activities in the mid-1990s. Our results show that, in spite of a comparatively late start, a considerable number of researchers engage in knowledge exchange processes with industry and other non-academic partners. We present evidence that suggests faculty in the social sciences and humanities as well as natural sciences and engineering maintain links to industrial partners, including multinational corporations. Furthermore, our observations indicate that schools differ in the way their faculty engage in university–industry collaborations. Further differences can be observed with respect to faculty attitudes towards technology transfer and awareness of the university’s respective codes of practice.