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Decades of research have shown that the brain atrophies after traumatic brain injury (TBI). However, multiple practical issues made it difficult to detect brain atrophy in individual patients with mild to moderate TBI. This situation improved by 2007 with the FDA approval of NeuroQuant®, a commercially available, computer-automated software program for measuring MRI brain volume in human subjects. Several peer-reviewed scientific studies have supported the reliability and validity of NeuroQuant®. This review addresses whether NeuroQuant® meets the Daubert standard for admissibility in court cases involving persons with TBI. The review finds that NeuroQuant® is an objective, reliable, and practical means of measuring brain volume and therefore can be an important tool for measuring the effects of TBI on brain volume in clinical or medicolegal settings. 相似文献
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Stuart Ross Marion Frere Lucy Healey Cathy Humphreys 《Australian Journal of Public Administration》2011,70(2):131-142
The Family Violence Reform strategy in Victoria is one of a number of contemporary government initiatives that have been framed within a whole of government model of policy reform. This article shows how the principles and processes of the whole of government approach were applied to the social problem of family violence. We examine the reasoning behind the adoption of this approach, what it was intended to achieve, the processes and activities that took place and stakeholders’ views about the outcomes and impact of this approach. The choice of a whole of government strategy reflected the need to address philosophical and organisational cultural differences about family violence and responses to it. Key elements were: the demonstrated commitment to reform and leadership provided by ministers, agency heads and senior managers; the involvement of community sector representatives; and the role of the Department of Planning and Community Development (DPCD). 相似文献
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Ross EC Polaschek DL Wilson M 《International journal of offender therapy and comparative criminology》2011,55(8):1308-1323
The Working Alliance Inventory (WAI) is the most widely used measure of the therapeutic alliance. However, previous studies of the factor structure of the WAI have obtained disparate results. This study examined ratings from three rater perspectives (therapists, clients, and observers) in a rehabilitation program for high-risk violent prisoners with high PCL-psychopathy scores. The authors used confirmatory factor analysis with a short version of the WAI and examined one-, two-, and three-factor models. It was hypothesized that the context and client characteristics could alter the factor structure of the ratings. However, no differences were found in factor structure by perspective; the results from all rater perspectives suggested that a two-factor structure was the best fit for the data. Thus, we concluded that therapists, observers, and prisoners all saw the goals and task aspects of the therapeutic alliance as distinct from the bond component. 相似文献
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This study assessed whether obesity significantly affects femoral shape. Femora of 121 white men were divided into two weight classes based on body mass index (BMI) of the deceased. Five external anteroposterior (AP) and mediolateral (ML) measurements were taken at consistent percentages of diaphyseal length. These were then subject to statistical tests. After controlling for age, multivariate statistics show a significant (p<0.05) effect of BMI on the femur, with the greatest significance in ML measurements. T-tests confirm these dimensions are significantly larger in the overweight (p<0.05). The effect of BMI on size-transformed and shape-transformed variables was also evaluated, with ANOVA results showing a significant BMI effect on ML size (p<0.05), but not shape. Significant size-transformed ML variables were then subject to discriminate function analyses with a cross-validation correction. Results show a correct classification rate of 88% in normal weight and 77% in overweight individuals. 相似文献
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Morphometric cranial variation among Spanish samples was compared to a 19th century Portuguese sample using both traditional and three-dimensional approaches. The Spanish samples included the regional 19th century Oloriz collection and the local 16-17th century Villanubla and Vallolid sample from northwestern Spain. Results suggest moderate variation among the samples and suggest that varying patterns of regional variation, sexual dimorphism and secular change represent important factors to be considered in the evaluation of population affinity using craniometric approaches. 相似文献