The detection and separation of antiparkinson preparations in cadaveric material by gas-liquid chromatography

Method of gas-chromatographic detection of anti-parkinsonism substances (amedine, amysile, dinesine, midantane, tropazine and cyclodole) isolated from the cadaveric material is suggested. Conditions for separation of anti-parkinsonism substances when they are all present in the cadaveric material are developed.     

Mitochondrial diversity of a northeast German population sample

Mitochondrial DNA sequences of the hypervariable regions HV I and HV II were analyzed in 300 unrelated individuals born and living in the northeast corner of Germany (Western Pomerania) to generate a database for forensic identification purposes in this region. Sequence polymorphism were detected using PCR and direct sequencing analysis. A total of 242 different haplotypes were found as determined by 147 variable positions. The most frequent haplotype (263G, 315.1C) was found in 10 individuals and is also the most common sequence in Europe. Three other haplotypes were shared by 5 individuals, 2 sequences by 4, 8 haplotypes by 3, 15 sequences by 2 persons, and 213 sequences were unique. The genetic diversity was estimated to be 0.99 and the probability of two random individuals showing identical mitochondrial DNA (mtDNA) haplotypes is 0.6%. A comparison with other studies from Germany showed only little differences in the distribution of haplogroups. Nevertheless, one frequent haplotype in northeast Germany (five unrelated individuals) could only rarely be found in other German and European regions. Our results may indicate that despite a high admixture proportion in the German population some regions could demonstrate certain characteristic features.     

The imprisoned nonviolent drug offender: Specialized martyr or versatile career criminal?

Some observers oppose imprisoning nonviolent drug offenders because they view incarceration as costly and such persons as generally benign. The careercriminal literature has established that perpetrators, including drug violators, commit an array of offenses. The current study merges these debates using a sample of 500 arrested adults selected from an urban jail in the western United States. Drug offenders amassed a much more extensive arrest history than other suspects net the effects of age, race, sex, prison history, and arrest onset. Drug offenders are quite versatile and do not conform to the image of specialized violators who are nominally criminal.