氯胺酮在急性中毒大鼠体内的死后再分布研究

目的探索氯胺酮在大鼠体内的死后再分布变化规律及温度对再分布的影响。方法48只雄性SD大鼠随机分为2个实验组（室温组24只、冷藏组18只）和1个对照组（6只）,实验组大鼠以氯胺酮290mg／kg灌胃,45min后缺氧处死,分别置于室温（24℃）和冷藏（4℃）条件下,于死后不同时间（0、12、24、48h）取心血、外周血、肝、肺、肾、心肌、大脑,检测其中氯胺酮含量;对照组大鼠以生理盐水灌胃,各对应组织器官样品为空白对照。血和组织样品中加入内标物SKF。。后碱化,乙酸乙酯萃取,GC／MS全扫描定性,内标法、工作曲线法气相色谱定量分析。结果室温条件下,大鼠死后48h内随着死亡时间延长,心血、肺、肝中氯胺酮的浓度呈升高趋势（P〈0．05）,肾脏中氯胺酮的浓度先升高后下降（P〈0．05）,外周血、心肌和脑中氯胺酮的浓度无显著性变化（P〉0．05）。冷藏条件下,血液及组织中氯胺酮浓度变化无显著性差异（P〉0．05）,除心肌外,各样本浓度均低于相应时段室温条件保存的样本。结论氯胺酮在大鼠体内存在死后再分布现象。温度对大鼠死后血液及组织中氯胺酮浓度变化有较明显的影响。     

Play context, commitment, and dating violence: a structural equation model

This study develops a structural equation model to describe the effect of two groups of factors (type of commitment and play context) on the violence experienced during intimate partner conflict. After contrasting the model in adolescents and university students, we have confirmed that aggressive play and the simulation of jealousy and anger increase the risk of dating victimization during conflicts through the negative reactions that they cause. Where commitment is concerned, the results are different according to whether commitment is personal or constraining. The former provides protection against dating victimization, reducing risk in the play context, whereas the latter has no effect on the violence experienced but facilitates a more dangerous play dynamic. The model can be applied in the design of programs to prevent dating violence.     

名人代言虚假广告的法律规制

近些年,请名人做产品广告或出任企业形象代言人之风盛行。但是,在名人代言的产品或服务广告中存在着违法、虚假内容,而我国相关法律、法规没有明确规定名人在虚假广告中的责任。应通过建立名人代言广告的审查及禁止准入制度;明确其代言虚假广告的法律责任;推进公益诉讼等来进行规制。     

关于犯罪现场勘查课程考核方式的思考

考核是教学的有机组成部分,考试的目的在于促进学生的学习,巩固他们所学知识,提高他们学以致用的能力。犯罪现场勘查学作为一门实践性很强的学科,其考核的方式对学生知识和能力的培养起着十分重要的意义,探讨当前犯罪现场勘查课程的考核方式并提出改革对策,有助于培养符合公安实战需要的合格人才。     

Do Pilot and Demonstration Projects Work? Evidence from a Green Building Program

Pilot and demonstration (P&D) projects are commonly deployed to catalyze early adoption of technology but are poorly understood in terms of mechanism and impact. We conceptually distinguish unique functions of pilots and demonstrations, then examine whether they accelerate adoption in the case of green building technology. To identify effects on adoption, we develop a difference-in-difference-in-differences strategy, exploiting variation in timing, location, and technologies of green building P&Ds. Results indicate local quarterly green building adoption rates double following completion of a P&D project. Further analyses examine mechanisms driving this effect. The results suggest green building demonstration projects create learning externalities, proliferating technology diffusion in local markets and through building owner networks. Together, these results suggest that investments in P&D projects by public and private actors can lower costs for subsequent adoption.     

牢记初心使命与推进自我革命的逻辑蕴涵

牢记初心使命与推进自我革命互为前提、相得益彰。从理论逻辑来看,牢记初心使命与推进自我革命本质一致;从历史逻辑来看,牢记初心使命与推进自我革命相辅相成;从现实逻辑来看,牢记初心使命与推进自我革命互为动力。揭示牢记初心使命与推进自我革命的内在蕴涵,打开牢记初心使命与推进自我革命在理论维度、时间维度和空间维度相互联结的视野,既有助于全党深入开展“不忘初心、牢记使命”主题教育活动,也有助于增强新时代中国共产党人勇于刀刃向内、不断自我革命的精神力量,从而锤炼政治品格,锻造过硬本领,永葆党的本色,始终如一践行初心,勇担使命。     

新形势下推进高校统战工作的路径探索

高校统战工作是党的统战工作的重要组成部分,新形势下呈现统战对象数量多、统战干部队伍人数少、统战工作任务难度大、统战工作制度不完善等新特点。由于受高校统战工作重要性认识、体制机制、干部队伍自身素质等因素制约,高校统战工作在取得显著成绩的同时,也存在一些问题和不足,亟需从强化高校统战意识、提升高校统战队伍素质、做好党外知识分子思想政治工作、健全统战工作的制度机制等方面采取切实措施,努力开创高校统战工作的新局面。     

Traumatic Events and Symptoms Among Mexican Deportees in a Border Community

Research on traumatic events experienced among Mexicans deported from the United States is scant. Using clinical interviews, this study assessed the frequency of traumatic events and symptoms of post-traumatic stress disorder (PTSD) among 47 Mexican deportees in a U.S.-Mexico border community. The majority of participants (98%) reported having experienced one or more traumatic events (M = 9, SD = 5) and nearly half met DSM-IV-TR criteria for PTSD. Meeting criteria for PTSD was associated with a higher number of traumatic events. Results suggest that prevention, intervention, and policy efforts are necessary to improve the well-being of this understudied immigrant subgroup.     

Personal Identity Development in Hispanic Immigrant Adolescents: Links with Positive Psychosocial Functioning,Depressive Symptoms,and Externalizing Problems

The present study was designed to examine trajectories of personal identity coherence and confusion among Hispanic recent-immigrant adolescents, as well as the effects of these trajectories on psychosocial and risk-taking outcomes. Personal identity is extremely important in anchoring young immigrants during a time of acute cultural change. A sample of 302 recently immigrated (5 years or less in the United States at baseline) Hispanic adolescents (M_age?=?14.51 years at baseline; SD?=?0.88 years, range 14–17) from Miami and Los Angeles (47?% girls) completed measures of personal identity coherence and confusion at the first five waves of a six-wave longitudinal study; and reported on positive psychosocial functioning, depressive symptoms, and externalizing problems at baseline and at Time 6. Results indicated that identity coherence increased linearly across time, but that there were no significant changes in confusion over time and no individual differences in confusion trajectories. Higher baseline levels of, and improvements in, coherence predicted higher levels of self-esteem, optimism, and prosocial behavior at the final study timepoint. Higher baseline levels of confusion predicted lower self-esteem, greater depressive symptoms, more aggressive behavior, and more rule breaking at the final study timepoint. These results are discussed in terms of the importance of personal identity for Hispanic immigrant adolescents, and in terms of implications for intervention.     

Effects of Indirect Exposure to Homicide Events on Children’s Mental Health: Evidence from Urban Settings in Colombia

Exposure to neighborhood violence is an important risk factor for the social and emotional development of children and youth. Previous work recognizes that violence may affect children indirectly via secondhand exposure; yet, few studies have aimed to identify and quantify these effects, especially in settings like Colombia where youth is chronically exposed to violence. To address this gap in the literature, this article implements an empirical strategy where geographically specific and time-stamped data are leveraged to identify the effect of indirect exposure to homicides on fifth grade children’s social and emotional outcomes. Sample participants (N?=?5801) represent the fifth-grade population of boys and girls (50.7%) in two major urban areas in the country (Mage?=?11.01, SD?=?0.75). We hypothesize that the effects of exposure to neighborhood violence on children’s social and emotional skills will be consistent and negative. The findings indicate a consistent negative effect of indirect exposure to homicides on children’s emotional functioning (i.e., emotional regulation and empathy), as well as on the prevalence of avoidance behaviors. However, contrary to theoretical expectations, the results do not support effects on children’s levels of aggressive behavior, nor on the beliefs and attitudes that justify the use of aggression in interpersonal relationships. The findings are discussed in light of predictions from social cognitive models and their implications for developmentally and trauma-informed interventions for youth.