Institutionalizing uncertainty: the choice of electoral formulas

Taken from an infinite set of divisors methods, the D’Hondt formula is the unique rule that maximizes the minimum number of seats for parties exceeding average size but not surpassing an absolute majority of the votes. This property is also shared, in the quota set of methods, by the Droop formula. At the same time, these two methods are those most commonly observed in practice. This paper relates the property stated to the observed facts. If parties try to maximize the minimum number of seats for a given share of votes, then the D’Hondt formula should be chosen. This choice is consistent with rational parties that make institutional choices in an uncertain environment.     

Social perceptions on genomics in four Latin American countries. Ethical-legal implications]

The authors analyze under an ethical and legal perspective the consequences and anxieties generated by the human genome project in the population of four Latin American countries: Argentine, Chile, México and Perú, through bibliographical analysis and interviews done to biomedical researches, lawyers and legislators, students and lay civilians.     

Risk Analysis of Nanomaterials: Exposing Nanotechnology's Naked Emperor

Risk analysis (encompassing risk assessment, management, and communication) is touted internationally as the most appropriate approach for governing nanomaterials. In this article, we survey existing criticisms of risk assessment as a basis for regulatory decision making on emerging technologies, particularly highlighting its exclusion of key societal dimensions, its epistemological underdetermination, and its lack of democratic accountability. We then review the specific case of nanomaterials and identify six major barriers to the effective operation of both risk assessment and risk management. These include a lack of: nano‐specific regulatory requirements, shared definitions, validated and accessible methods for safety testing, available scientific knowledge, reliable information on commercial use, and capacity for exposure mitigation. Finding the knowledge, standards, methods, tools, definitions, capacity, and political commitment all insufficient, we argue that risk analysis is a “naked emperor” for nanomaterial governance. We therefore suggest that additional concepts and approaches are essential for nanomaterials policy and regulation.     

Real-time PCR designs to estimate nuclear and mitochondrial DNA copy number in forensic and ancient DNA studies

We explore different designs to estimate both nuclear and mitochondrial human DNA (mtDNA) content based on the detection of the 5' nuclease activity of the Taq DNA polymerase using fluorogenic probes and a real-time quantitative PCR detection system. Human mtDNA quantification was accomplished by monitoring the real-time progress of the PCR-amplification of two different fragment sizes (113 and 287 bp) within the hypervariable region I (HV1) of the mtDNA control region, using two fluorogenic probes to specifically determine the mtDNA copy of each fragment size category. This mtDNA real-time PCR design has been used to assess the mtDNA preservation (copy number and degradation state) of DNA samples retrieved from 500 to 1500 years old human remains that showed low copy number and highly degraded mtDNA. The quantification of nuclear DNA was achieved by real-time PCR of a segment of the X-Y homologous amelogenin (AMG) gene that allowed the simultaneous estimation of a Y-specific fragment (AMGY: 112 bp) and a X-specific fragment (AMGX: 106 bp) making possible not only haploid or diploid DNA quantitation but also sex determination. The AMG real-time PCR design has been used to quantify a set of 57 DNA samples from 4-5 years old forensic bone remains with improved sensitivity compared with the slot-blot hybridization method. The potential utility of this technology to improve the quality of some PCR-based forensic and ancient DNA studies (microsatellite typing and mtDNA sequencing) is discussed.     

Validation of the Attitudes About Aggression in Dating Situations (AADS) and the Justification of Verbal/Coercive Tactics Scale (JVCT) in Spanish Adolescents

The aim of this study was to analyze the psychometric properties of two instruments that assess attitudes justifying use of aggression in adolescents?? dating relationships: the Attitudes About Aggression in Dating Situations (AADS) and the Justification of Verbal/Coercive Tactics Scale (JVCT). The sample was made up of 2,856 adolescents from different high schools of Madrid. Results supported the three-factor structure for the AADS and the six-factor structure for the JVCT, which was consistent with the theory and with previous research. As expected, the relation between attitudes and aggressive behavior was between small and moderate but significant in most cases. Furthermore, attitudes differed depending on the type of violence, the respondent??s sex, and on whether aggression is carried out by a man or a woman. Finally, the potential applications of these two scales are discussed, and it is concluded that both constitute useful tools to assess justification of aggression in dating relationships in young couples.     

Age estimation through histological study of trabecular volume and cortical bone width of the iliac crest

There have been many methods proposed to estimate the age of human bones in forensic medicine or in forensic anthropology, including those that assess histological structures. In this study, age was evaluated through the histomorphometric study of trabecular volume and cortical width of the right iliac crest. A total of 25 samples A total of 66 samples (42 male and 24 female) were obtained from necropsies of judicial cases, with ages ranging from 13 to 58years, who had died a sudden or violent death. The samples were obtained using Bordier's trocar for bone biopsy, in a period not exceeding 24h after death. The samples were examined without decalcification, with 96° alcohol dehydration, embedding in methyl methacrylate, and sectioned with a microtome Reichert (3μm). The sections were fixed on microscope slides and stained using toluidine blue, Goldner trichrome and hematoxylin-eosin methods. The samples were studied under a Leica DM LB microscope and the images were digitally captured. The digital images were processed using an image analysis program and data were analyzed using the SPSS statistical package. The results demonstrated that the combination of the trabecular volume and cortical width acted as predictors of the age in subjects which did not suffer from any deterioration of bone and/or mineral metabolism.     

The Association between Maternal Exposure to Intimate Partner Violence and Emotional and Behavioral Problems in Spanish Children and Adolescents

This correlational cross-sectional study was designed to investigate whether the intimate partner violence (IPV) suffered by mothers (physical and psychological maltreatment), the neglect suffered by children, and the maltreatment (physical and psychological) directly suffered by children are statistically associated with an increase in the probability of the child’s suffering psychopathological problems. The sample consisted of 189 Spanish children aged 6 to 17 and their mothers, recruited from Centers of Specialized Assistance for Women Victims of IPV. The results of a canonical correlation analysis showed that the most significant problems suffered by the children were both externalizing and internalizing ones. In girls, the maltreatment suffered by their mothers was directly related to a larger frequency of somatic complaints than in boys. In addition, physical maltreatment to the mother and emotional maltreatment suffered by the child exhibited a statistically significant relationship with aggressive behaviour, thought problems, rule-breaking behaviour, attention problems, and withdrawn-depressed.     

A NOT SO MODEST PROPOSAL TO HUMANIZE THE LEGAL PROFESSION

This article first appeared in the Los Angeles County Bar Association's Family Law Section quarterly , News and Review. In a very personal and insightful way, the author examines the change which women have brought to the practice of family law .     

The 2000-2001 GEP-ISFG Collaborative Exercise on mtDNA: assessing the cause of unsuccessful mtDNA PCR amplification of hair shaft samples

We report the results of Spanish and Portuguese working group (GEP) of International Society of Forensic Genetics (ISFG) Collaborative Exercise 2001-2002 on mitochondrial DNA (mtDNA) analysis. 64 laboratories from Spain, Portugal and several Latin-American countries participated in this quality control exercise. Five samples were sent to the participating laboratories, four blood stains (M1-M4) and a sample (M5) consisting of two hair shaft fragments. M4 was non-human (Felis catus) in origin; therefore, the capacity of the labs to identify the biological source of this sample was an integral part of the exercise. Some labs detected the non-human origin of M4 by carrying out immuno-diffussion techniques using antihuman serum, whereas others identified the specific animal origin by testing the sample against a set of animal antibodies or by means of the analysis of mtDNA regions (Cyt-b, 12S, and 16S genes). The results of the other three human blood stains (M1-M3) improved in relation to the last Collaborative Exercises but those related to hairs yielded a low rate of success which clearly contrasts with previous results. As a consequence of this, some labs performed additional analysis showing that the origin of this low efficiency was not the presence of inhibitors, but the low quantity of DNA present in these specific hair samples and the degradation.As a general conclusion the results emphasize the need of external proficiency testing as part of the accreditation procedure for the labs performing mtDNA analysis in forensic casework.     

Are regulatory agencies independent in practice? Evidence from board members in Spain

Are the board members of regulatory agencies (regulators), taken as a particular cluster within the public sphere, independent of elected politicians and tenured bureaucrats? How can we assess their independence in practice, beyond formal rules? To address these questions, this paper delves into two key dimensions: board members' social connections and their security of tenure in office. Firstly, we focus on regulators' identity as policy adjudicators and examine their political and administrative relations. In doing so, we expect to understand better how regulators' social and political situations may influence their behavior. Secondly, we assess their political vulnerability through political cycles in order to measure their de facto independence over time. Additionally, variations in these two dimensions are compared with respect to the effect of different de jure appointment rules. We contrast these expectations with the empirical evaluation of board members of regulatory agencies in Spain (1979–2010). Thus, we confirm that regulators who have an administrative profile are more vulnerable to political changes than those with political ties, while appointment rules have an influence on their political vulnerability.