Sudden infant death syndrome (SIDS)--standardised investigations and classification: recommendations

Sudden infant death syndrome (SIDS) still accounts for considerable numbers of unexpected infant deaths in many countries. While numerous theories have been advanced to explain these events, it is increasingly clear that this group of infant deaths results from the complex interaction of a variety of heritable and idiosyncratic endogenous factors interacting with exogenous factors. This has been elegantly summarised in the "three hit" or "triple risk" model. Contradictions and lack of consistencies in the literature have arisen from diverse autopsy approaches, variable applications of diagnostic criteria and inconsistent use of definitions. An approach to sudden infant death is outlined with discussion of appropriate tissue sampling, ancillary investigations and the use of controls in research projects. Standardisation of infant death investigations with the application of uniform definitions and protocols will ensure optimal investigation of individual cases and enable international comparisons of trends.     

Bacteria in lung tissue from an autopsy population of alcoholics

The retrieval of bacteria from the lungs postmortem was examined in a population of alcoholics who had a medico-legal autopsy performed. The results were compared with non-alcoholic controls. Pneumococci were found more frequently in alcoholics, but in general there were no major differences. Proteus mirabilis was detected in three out of five alcoholics with unascertainable cause of death. It is speculated whether this species may cause septicaemia in some alcoholics due to abnormal splanchnicus circulation.     

Extraction of DNA from decomposed human tissue. An evaluation of five extraction methods for short tandem repeat typing

Hyperpolymorphic short tandem repetitive DNA sequences, STRs or microsatellites, have become widely used in human identification, particularly in criminal cases and in mass disasters. In such cases the substrates for the analyses may be decomposed biological material, a fact that has to be taken into account when choosing the appropriate casework methods. In this paper we report the evaluation of five different DNA extraction methods, namely the phenol-chloroform, the silica based, the InstaGene Matrix (BioTest), the glass fiber filter, and the Chelex based methods. The substrates for the analyses are decomposed human liver tissue specimens from forensic autopsy cases. Extracted DNA was quantified and DNA profiled by a set of seven STRs. We have compared laboratory time consumption and costs of the five methods, showing that the Chelex method is the more rapid and less expensive of the methods, the phenol-chlorophorm and silica extractions being the most time consuming and resource demanding ones. A full profile was obtained by the silica method in nine out of ten cases and this method failed to give a reliable type in four out of 70 STR analyses. The phenol-chlorophorm and the glass fiber filter methods failed in 16 analyses, the InstaGene Matrix (BioTest) in 25 and the Chelex extracts in 56 of the 70 STR analyses. By multiple logistic regression we show that the difference between the silica procedure and the other methods are statistically significant. In our hands, the silica gel extraction procedure is an obvious choice when the biological material available is decomposed human tissue--even if this procedure is one of the more laborious ones.     

Death of a 10‐Month‐Old Boy After Exposure to Ethylmorphine

Abstract: Ethylmorphine, an opiate that is partially metabolized to morphine, is a common ingredient in antitussive preparations. We present a case where a 10‐month‐old boy was administered ethylmorphine in the evening and found dead in bed the following morning. Postmortem toxicological analyses of heart blood by gas chromatography‐mass spectrometry and liquid chromatography‐mass spectrometry revealed the presence of ethylmorphine and morphine at concentrations of 0.17 μM (0.054 mg/L) and 0.090 μM (0.026 mg/L), respectively. CYP2D6 genotyping showed that the deceased had an extensive metabolizer genotype, signifying a “normal” capacity for metabolizing ethylmorphine to morphine. The autopsy report concluded that death was caused by a combination of opiate‐induced sedation and weakening of respiratory drive, a respiratory infection, and a sleeping position that could have impeded breathing. This is the first case report where the death of an infant has been linked to ethylmorphine ingestion.     

China in the Asia–Pacific Partnership: consequences for UN climate change mitigation efforts?

This article discusses China’s motives for participation in the Asia–Pacific Partnership on Clean Development and Climate (APP), and whether this has or will have consequences for its participation and efforts in the UN track of international climate governance. In order to discuss these issues, it also provides an outline of key national priorities and explains the nature of China’s involvement in both the UN track and the APP. It suggests that the APP is a complement to the UN process, not a competitor, in the case of China. APP participation represents a win–win situation in terms of the transfer of technology and know-how for solving challenges related to energy security and greenhouse gas emissions. For the Chinese leadership, this seems preferable to taking on UN commitments which it fears would impede economic development. The APP’s projects also seem to complement the Kyoto Protocol’s Clean Development Mechanism project in China. This article argues that there is little indication that China would make less of an effort under the UN track.

Contradictions in Participatory Public Art: Placemaking as an Instrument of Urban Cultural Policy

This article addresses the current focus within urban cultural policy on using art as a tool in urban development. Based on theories of participation, democracy, and public art, the article sets out to investigate critically the concept of placemaking. The discussion is based on an analysis of the public art project Placemaking, which took place during 2015 in eight municipalities around Copenhagen in Denmark. I argue that, when used as a tool in urban development, participatory public art engenders contradictory encounters. These encounters challenge the cultural political effort to democratize art and culture.     

Differences in intimate partner homicides perpetrated by men and women: evidence from a Norwegian National 22-year cohort

Most of our knowledge about intimate partner homicide (IPH) is based on studies of men, as they outnumber women as perpetrators. From a total cohort of IPHs in Norway from 1990 to 2012 (N?=?177), we investigated differences between male (n?=?157) and female (n?=?20) perpetrators in terms of (a) IPH characteristics and sentencing issues, (b) sociodemographic, contextual and clinical factors, and (c) previous intimate partner violence. Multivariate logistic regression analyses indicated that, in comparison to male perpetrators, female perpetrators were more often in intimate partnerships without mutual children, had a greater number of accumulated welfare deficiencies, and tended to be ascribed different motives (fear and revenge) for their crimes.     

Islam,médias,mise en place du Sénat et article 37 de la Constitution: changement de paradigme au Burkina Faso (1991–2014)?

Abstract

In the context of socio-political liberalisation, which has been happening since 1991, together with the competition between the different religions in the public arena in Burkina Faso, the visibility of Islam has increased considerably with the creation of Islamic media and the growing use of the Internet. This article examines the impact of the growing mediatisation of Islam on the agency and the content of the discourse of Muslim elites in Burkina Faso. This has led to the emergence of new, very mediatised religious figures who have gained authority in the public arena. However, the multiplication of the Islamic message is not accompanied by greater politicisation. Their agency resides rather in their relative capacity to invest in the public arena to defend their vision of society governed by Islamic moral norms. The debate surrounding the introduction of the Senate and the revision of Article 37 of the Constitution between 2011 and 2014 has shown the lacklustre agency of the Muslim leaders.     

Shaping Political Preferences: Information Effects in Political-Administrative Systems

Information is at the heart of politics. However, since information is always sent by someone who is more or less powerful, it is difficult to disentangle the effect of information from the power of the sender. Drawing on a standard model of attitude formation, we argue that presenting information can affect preferences of politicians regardless of the power of the sender. We test this proposition in a survey experiment with 1205 Danish local politicians in which the experimental groups were presented with varying levels of cost information but where sender remained constant. The experiment shows that even in a setting where the information is not disclosed by a powerful sender, information may have a stronger impact on political preferences than other well-known determinants such as committee and party affiliation. Our findings speak to learning theories, knowledge perspectives and the literature on the determinants of politicians’ preferences.