Partial Agonist Therapy in Schizophrenia: Relevance to Diminished Criminal Responsibility

Abstract: Pathological gambling (PG), classified in the DSM‐IV among impulse control disorders, is defined as inappropriate, persistent gaming for money with serious personal, family, and social consequences. Offenses are frequently committed to obtain money for gambling. Pathological gambling, a planned and structured behavioral disorder, has often been described as a complication of dopamine agonist treatment in patients with Parkinson’s disease. It has never been described in patients with schizophrenia receiving dopamine agonists. We present two patients with schizophrenia, previously treated with antipsychotic drugs without any suggestion of PG, who a short time after starting aripiprazole, a dopamine partial agonist, developed PG and criminal behavior, which totally resolved when aripiprazole was discontinued. Based on recent advances in research on PG and adverse drug reactions to dopamine agonists in Parkinson’s disease, we postulate a link between aripiprazole and PG in both our patients with schizophrenia and raise the question of criminal responsibility.     

Genetic study of 15 STRs loci of Identifiler system in Angola population

Angola is located in the African continent, in the area of southern Africa and has a population of approximately 14 million inhabitants. The Angola population has origin from Occidental and Southern Bantu people that came from the great lakes region, creating the most ever known African migration of our days.Allele frequencies for the 15 STRs loci in the AmpFlSTR Identifiler kit (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, HUMTH01, D13S317, D16S539, D2S1338, D19S433, HUMVWA, TPOX, D18S51, D5S818, HUMFIBRA/FGA and including the segment of the X-Y homologous gene amelogenin) were studied for Angola population.The genotype frequency of the 15 STR loci showed no significant deviations from Hardy–Weinberg equilibrium expectations and great values for the combined power of discrimination and combined power of a priori exclusion validate the application of these markers in forensic genetics. Comparative analyses between Angola population data and other relevant population database from Africa, Europe and American are presented.     

Temporal Trends in Rainwater Tank Suicides in Rijeka,Croatia—A 30‐year Study

Although drowning in rainwater tanks is a generally rare phenomenon, this method for suicide has been observed in parts of Croatia. Review of autopsy records at the University of Rijeka, Croatia, was undertaken from 1987 to 2016 to examine this phenomenon. Of 469 drowning deaths, there were 35 suicides in rainwater tanks (7.5%). Overall drowning deaths showed no temporal trends. In contrast, suicidal drownings in rain water tanks showed a marked decline over the years, with 15 cases in 1987–1991, seven in 1992–1996, six in 1997–2001, six in 2002–2006, one in 2007–2011, and none in 2012–2016. Thus, suicidal drowning cases as a percentage of overall drownings dropped from 18% to zero (p<0.001). This study reports a very unusual method of suicide that may have occurred because of the ready availability of large water reservoirs in homes. The recent fall in numbers may relate to less reliance on domestic reservoirs of water.     

Escaping the merchant/missionary dilemma: an imperial policy for the Asia-Pacific

The Asia policy of the Bush administration follows from two principles: its preference for ‘hub-and-spoke relationships’ led from Washington, and the restored priority of security issues over the mixture of trade interests and human rights that was the hallmark of the Clinton presidency. The initial focus of the administration on the restoration of political and strategic ties with old allies such as Japan, and on strategic competition, has been mitigated by another realistic approach: the need to seek new allies and partnerships. This policy was already evident towards India before September 11, 2001, but has been magnified with the onset of a coalition against terrorism, and almost as importantly, against the proliferation of weapons of mass destruction. The resumption of strategic and military ties with China, the priority of anti-terrorist cooperation over human rights issues with Southeast Asia, the increased support for India that is of more strategic value than America's tactical involvement with Pakistan, are developments that overshadow the US relationship with traditional allies such as Japan or the European Union. The major weakness of the Bush Asia policy, however, is its relative neglect of major economic and social issues in the region. Although support for some weakened ASEAN economies has increased, there is neither a more intense coordination of economic policies with Japan, in spite of initially declared intentions, nor a major economic and social strategy for Southeast and South Asia that would support the fight against terrorism.     

Population and income: Is there a puzzle?

Abstract

This note presents wide evidence on the relationship between population and income for 125 countries for which data was available for the period 1950–2000. The main result is that there is a weak but negative relationship between population growth and per capita GDP, as income increases population expands at a slower rate. This relationship appears to be stronger for African countries and for Asian countries before 1970.     

Turnout and presidential coattails in congressional elections

Estimating the impact of turnout on House election results is problematic because of endogeneity and omitted variable bias. The following study proposes an instrumental approach to correct for these problems by using a series of fixed effects two-stage least squares panel-data regression models covering three congressional apportionment cycles (1972–1980; 1982–1990; 1992–2000). The analysis tests whether voter participation decreases the House incumbent’s electoral support, regardless of the level of competition in the district. The study also aims to determine if an increase in participation benefits Democratic candidates and whether this effect is constant across apportionment cycles. The results show that the influence of turnout on incumbency vote share is conditional on the level of presidential support in the district. This finding is explained by the surge and decline thesis of Campbell (1960).     

Social Capital and Hygiene Practices among the Extreme Poor in Rural Bangladesh

We investigate the effect of social capital on hygiene practices pertaining to lives of the extreme poor in rural Bangladesh. Analysing a unique survey dataset for 5,600 extreme poor households, we document a significant positive effect of social capital on sanitary latrine use and wearing shoes/sandals at home for hygiene. We account for the endogeneity of social capital by instrumental variable estimation. Our findings emphasise the role of social capital in preventing common diseases through improving hygiene practices for the extreme poor, who usually lack access to medical services in the event of illness, which has important policy implications.