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Hopwood AJ Puch-Solis R Tucker VC Curran JM Skerrett J Pope S Tully G 《Science & justice》2012,52(3):185-190
The adoption of new 15 locus STR multiplex systems into UK forensic science would be facilitated by agreed guidelines for reporting the strength of DNA evidence using likelihood ratios. To facilitate such an agreement, we present an analysis of previously published UK allele frequencies for white Caucasian, Afro-Caribbean and Indo-Pakistani populations and investigate their effect on likelihood ratios for single donor profiles. We consider the implication of the five additional loci and suggest a procedure for reporting likelihood ratios for 15-plex STR profiles. 相似文献
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Evaluation of Degradation in DNA from Males with a Quantitative Gender Typing,Endpoint PCR Multiplex 下载免费PDF全文
Byron C. Smith M.S.F.S. Emily Vandegrift M.S.F.S. Valerie Mattimore Fuller Ph.D. Robert W. Allen Ph.D. School of Forensic Sciences 《Journal of forensic sciences》2015,60(2):399-408
Evidentiary samples submitted to a forensic DNA laboratory occasionally yield DNA that is degraded. Samples of intact chromosomal DNA (both nuclear and mitochondrial) were subjected to a heating protocol to induce DNA degradation. The DNAs were then analyzed using a multiplex PCR assay that amplifies targets of low and high molecular weight on the X/Y and mitochondrial chromosomes. If degradation is random, the amplification of larger DNA targets should be more adversely affected by degradation than smaller targets. In nuclear and mitochondrial DNA from a male donor, exhibiting degradation, DNA quantity estimates based upon higher molecular weight amplicons (HMW) are significantly lower than estimates made using low molecular weight (LMW) Q‐TAT amplicons. DNA degradation estimated using this approach correlated well with actual fluorescence associated with HMW and LMW STR alleles amplified from the same genomic DNA templates. Q‐TAT is thus useful not only as a quantitation tool, but also as an indicator of template degradation. 相似文献
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The judgment of the Federal Court of Australia (the Court)in Universal Music is the first judicial pronouncement in Australiaon the legality of website operators who provide hyperlinksto remote websites to allow internauts (web users)to download MP3 music files and the liability of internet serviceproviders (ISPs) and their employees for authorizing that infringementunder Australian copyright law. 相似文献
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Norma Fuller 《Development in Practice》2009,19(6):752-758
This article discusses the ethical challenges posed to anthropologists working as experts in mining companies and in tourism. It proposes alternative solutions that are coherent with the ethical principles of their discipline. 相似文献