Practical experiences in application of hair fatty acid ethyl esters and ethyl glucuronide for detection of chronic alcohol abuse in forensic cases

This article presents results from 1872 hair samples, which were analyzed for fatty acid ethyl esters (FAEEs) and ethyl glucuronide (EtG). The results were evaluated in the context of self-reported drinking behavior, the use of hair cosmetics, the gender of the sample donors and hair sample length. For comparison, CDT and GGT in serum were available in 477 and 454 cases, respectively. A number of alcohol abstainers or low moderate drinkers and excessive drinkers were selected for assessment of cut-offs for FAEEs in the proximal 6cm hair segments and for EtG in the proximal 3cm hair segments. Cut-off values were assessed by ROC analysis. It was found that the cut-offs of 1.0ng/mg FAEE and 30pg/mg EtG presently used for excessive drinking lead to a low portion of false positives (4% and 3% respectively) but to a higher portion of false negatives (23% and 25% respectively). Comparison of the mean and medium concentrations in samples without any reported hair cosmetics (N=1079) and in samples with reported use of hair spray (N=79) showed an increase by the factor of about two for FAEE but no significant difference for EtG. Mean values of EtG were decreased by 80% in bleached samples (N=164) and by 63% in dyed samples (N=96). There was no significant effect of bleaching and dyeing on FAEE. Hair gel and hair wax, oil or grease showed no significant effect on both FAEE and EtG. With respect to gender and investigated hair length ambiguous results were obtained because of major differences in the compared subpopulations of male with higher alcohol consumption and mainly shorter hair, and less drinking female with longer hair. For excessive drinkers FAEEs in the 0-6cm hair segment and EtG in the 0-3cm segment decreased with increasing time of reported abstinence before sample collection. These drinkers attain the level of teetotalers only after more than 10 months of abstinence. In comparison to scalp hair, FAEEs recovered from armpit hair and leg hair were lower and from chest hair were higher. EtG in armpit hair was lower and in leg hair higher than in scalp hair. It is concluded that the combined use of FAEE and EtG essentially increases the accuracy of interpretation since both markers complement each other by a different sensitivity to sources of error.     

Depressive Symptoms, Stress, and Support: Gendered Trajectories From Adolescence to Young Adulthood

Stressful transitions in adolescence increase depressive symptoms, especially among girls. However, little is known about this risk as adolescents mature into young adulthood, especially about how parental support affects depression trajectories during this period. Using the National Longitudinal Study of Adolescent Health, this analysis investigates the role of gender in structuring the associations among stressful life events, parental support, and depression. Females reported more depressive symptoms at the outset of the study, a rank order that persisted along declining depression trajectories into young adulthood. In addition, stress accounts for the decline in trajectories for females but not males. Support from both parents has a salubrious effect on mental health, regardless of gender, but this effect dissipates as adolescents age into adulthood.     

Canadian energy security: the state of Canada's emergency preparedness system

Abstract: Because Canada has regions totally dependent on imported oil and is a trading nation dependent on international trade for a significant share of its national income, it is vulnerable both directly and indirectly to the consequences of oil supply shortfalls and the attendant price hikes. The Canadian energy emergency preparedness system, through Canada's membership in the International Energy Agency, is integrated into the iea's international emergency oil-sharing system. Despite being well over a decade old, the nature and state of Canada's system has never been independently analysed. By highlighting the close relationship between energy security and economic security, the argument is made that continued attention to energy security is prudent. The article attempts to make the very technical features of these systems comprehensible to non-energy specialists. The implications of iea membership for Canada are analysed and the relationship between Canada's responsibilities to the iea and its obligation under the free trade agreement with the United States is discussed. Sommaire: Dans la mesure où il a des régions entièrement dépendantes des importations de pétrole et où il est tributaire du commerce international pour une part importante de son revenu national, le Canada est vulnérable directement et indirectement aux conséquences d'un arrêt des approvisionnements pétroliers et aux montées des prix en résultant. Le plan d'urgence énergétique dont le Canada s'est doté dans le cadre de son appartenance à I'Agence Internationale de 1'Énergie est intégré au système international de partage de pétrole en cas d'urgence élaborré par cet organisme. Bien qu'il existe depuis plus d'une décennie, la nature et la situation du plan canadien n'ont jamais étéétudiées de façon indépendante. En attirant I'attention des lecteurs sur les relations étroites existant entre la sécurité en matière énergétique et en matière économique, les auteurs expliquent qu'il est prudent de prêter constamment attention à la sécurité en matière énergétique. 11s essaient égale-ment de vulgariser les caractéristiques extrêmement techniques de ces systèmes. Les auteurs analysent en outre les conéquences qu'entraîne ^Pappartenance du Canada à I'AIE et le rapport existant entre les responsabilités du Canada vis-à-vis de I'AIE et ses obligations dans le cadre de I'accord de libre-échange avec les États-Unis.     

The theory of planned behavior and policing: how attitudes about behavior,subjective norms,and perceived behavioral control affect the discretionary enforcement decisions of police officers

This research used qualitative methods to investigate police officer decision-making processes within the context of the theory of planned behavior from the discipline of psychology. Interviews with police officers were conducted to elicit how the constructs of attitudes about enforcement behaviors, subjective norms, and perceived behavioral control manifest themselves in a policing context and how they affect the enforcement decisions that police officers ultimately make. The results indicated that officer attitudes about enforcement behaviors impact the decisions officers make with the caution that the impact of these attitudes varies across varying situational contexts. In terms of subjective norms, officers were primarily concerned with supervisor expectations more than the expectations of coworkers or the community in general. Officer decisions are also impacted by perceived limits on their discretion with these perceived limits being largely conditioned by offense seriousness. Theoretical implications of the findings and directions for future research are discussed.     

The effects of IMF programs on U.S. foreign direct investment in the developing world

Given the popular wisdom that the U.S. government influences IMF policies and tends to support the business community, it might be expected that IMF programs benefit U.S. firms abroad and thus borrower nations are attractive destinations for U.S. foreign direct investment (FDI). Surprisingly, no study has tested the impact of IMF loans on U.S. FDI. Controlling for common explanations in the literature, we use a treatment effects model and interviews with IMF staff researchers to investigate whether countries under different kinds of IMF programs receive more U.S. FDI than countries not under IMF arrangements. Using panel data for 126 developing countries from 1980 to 2003, we find that IMF borrowers tend to be more attractive to U.S. investors but not all IMF programs have the same effect. Our findings suggest that differences in loan duration, the extent of borrower input in policy decisions, and loan amounts affect borrowers’ leverage with the Fund and the U.S.     

Jump-Starting Collaboration: The ABCD Initiative and the Provision of Child Development Services through Medicaid and Collaborators

Many policy problems require governmental leaders to forge vast networks beyond their own hierarchical institutions. This essay explores the challenges of implementation in a networked institutional setting and incentives to induce coordination between agencies and promote quality implementation. It describes the national evaluation of the Assuring Better Child Health and Development program, a state-based program intended to increase and enhance the delivery of child development services for low-income children through the health care sector, using Medicaid as its primary vehicle. Using qualitative evaluation methods, the authors found that all states implemented programs that addressed their stated goals and made changes in Medicaid policies, regulations, or reimbursement mechanisms. The program catalyzed interagency cooperation and coordination. The authors conclude that even a modest level of external support and technical assistance can stimulate significant programmatic change and interorganizational linkages within public agencies to enhance provision of child development services.     

The national residency exchange: a proposal to restore primary care in an age of microspecialization

Healthcare deficiencies in the United States have long been perpetuated by a shortage of primary care providers. A core purpose of the Patient Protection and Affordable Care Act (PPACA) is to provide health insurance for America's approximately fifty million uninsured. Implementation of universal health insurance, however, does not mean sufficient healthcare access for all, since the supply of physicians does not and will not meet demand. For reasons reviewed in this Article, the current physician shortage mainly impacts primary care providers. This shortage is particularly troubling because increased provision of primary care relative to specialty care has been associated with improvement in health outcomes, disease prevention, cost effectiveness, and coordination of care. This Article highlights provisions in the PPACA that impact primary care physicians. Finally, this Article proposes the creation of a universal primary care loan repayment program and a national residency exchange designed to alleviate the U.S. primary care crisis by facilitating optimal distribution of resident physicians in each medical specialty based on community need.