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This report describes a method for subtyping haptoglobin by means of isoelectric focusing in 0.2-mm ultrathin-layer polyacrylamide gels. Haptoglobin (Hp) is purified by ion-exchange chromatography and reduced. The well-known advantages of ultrathin-layer gels combine high isoelectrophoretic resolution of the Hp subtypes with less demands for time and material and make sequential visualization by fixation and protein staining possible. The distribution of the Hp subtypes in 1500 unrelated adults from Hanover and Lower Saxony is presented. Allelic frequencies are calculated to be: Hp*2FF = 0.0030; *2FS = 0.5620; *2SS = 0.0290; *1F = 0.1537; *1S = 0.2523. Segregation analysis for 68 matings shows an autosomal codominant mode of transmission in all cases. For the population investigated the chance of isolated paternity exclusion with the subtyped Hp system amounts to 33.91%. 相似文献
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Guenther Roth 《Society》1990,27(2):63-69
An expanded version of his English introduction to Marianne Weber’s biography of Max Weber was published in the Transaction
edition. A companion piece on “émile Durkheim and the Principles of 1789: The Issue of Gender Equality,” appears in Telos. 相似文献
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Using propensity score matching, this study examines the effects of migration on various indicators of household wellbeing in Cambodia. The results indicate that migration would reduce poverty headcount rate by 3–7 percentage points and decrease the depth of poverty. Migration is also found to reduce by 5–10 per cent the hours worked by members left-behind. The impact of migration on labour participation may be, however, vulnerable to unobservable factors. Nevertheless, the study suggests that important heterogeneous effects which differ from the average impact exist. The analysis is conducted separately by internal and international migration. 相似文献