Stable isotope ratios as a tool in microbial forensics--Part 1. Microbial isotopic composition as a function of growth medium

The stable isotope ratios of a seized pathogen culture could potentially reveal information about the environment in which the agent was produced. In this paper we describe general relationships between stable isotopes of carbon, nitrogen, and hydrogen in bacteriological culture media and spores of Bacillus subtilis, an endospore-forming soil bacterium. In numerous media that varied both in nutrient composition and water stable isotope ratios, medium to spore enrichment in carbon isotopes was 0.3 +/- 2.0% per thousand (parts per thousand), and in nitrogen, 4.5 +/- 0.7% per thousand. We achieved mass balance for the contribution of hydrogen isotopes from nutrients (70%) and water (30%) to spores in independent experiments by varying the isotope ratios of nutrients or water. A model was derived for predicting the isotope ratio values of spores from those in nutrients and water.     

The incidence of drugs in drivers killed in Australian road traffic crashes

The incidence of alcohol and drugs in fatally injured drivers were determined in three Australian states; Victoria (VIC), New South Wales (NSW) and Western Australia (WA) for the period of 1990-1999. A total of 3398 driver fatalities were investigated which included 2609 car drivers, 650 motorcyclists and 139 truck drivers. Alcohol at or over 0.05 g/100ml (%) was present in 29.1% of all drivers. The highest prevalence was in car drivers (30.3%) and the lowest in truckers (8.6%). WA had the highest rate of alcohol presence of the three states (35.8%). Almost 10% of the cases involved both alcohol and drugs. Drugs (other than alcohol) were present in 26.7% of cases and psychotropic drugs in 23.5%. These drugs comprised cannabis (13.5%), opioids (4.9%), stimulants (4.1%), benzodiazepines (4.1%) and other psychotropic drugs (2.7%). 8.5% of all drivers tested positive for Delta(9)-tetrahydrocannabinol (THC) and the balance of cannabis positive drivers were positive to only the 11-nor-Delta(9)-tetrahydrocannabinol-9-carboxylic acid (carboxy-THC) metabolite. The range of THC blood concentrations in drivers was 0.1-228 ng/ml, with a median of 9 ng/ml. Opioids consisted mainly of morphine (n=84), codeine (n=89) and methadone (n=33), while stimulants consisted mainly of methamphetamine (n=51), MDMA (n=6), cocaine (n=5), and the ephedrines (n=61). The prevalence of drugs increased over the decade, particularly cannabis and opioids, while alcohol decreased. Cannabis had a larger prevalence in motorcyclists (22.2%), whereas stimulants had a much larger presence in truckers (23%).     

The Emperor's New Clothes: A moral tale for development experts?

While global problems of poverty, inequality, and social upheaval are on the increase, the language used by development agencies and development experts sounds increasingly radical and idealistic. New socio-political conditions have been borrowed from real contexts in the South, only to be re-imposed on Southern 'partners'. Notions like empowerment, participation, and governance are paradoxically enforced through top-down, external intervention. Hans Christian Andersen's parable of the Emperor's new clothes highlights the illusory nature of this re-packaging of development policies in the 1990s. One major difficulty is that micro- and meso-level socio-political conditionalities remain subordinated to macro-level economic liberalisation. They look participatory from a distance, but at close quarters these measures have effectively become new forms of management and control, which are just as costly [as the old methods] but do not result in great benefits to project participants. (Craig and Porter 1997:50, commenting on the current vogue for mainstreaming of participation in development projects) Beautiful images of the high goals of the official development discourse and deep internal turbulence were clearly interdependent [but] contradictions between the discourse of goals and means and what is actually being achieved may not be visible any more. (Quarles van Ufford 1995:4, 12-13, 14)     

Women's Studies: Between a Rock and a Hard Place or Just Another Cell in the Beehive?

The article traces the history of Women's Studies from its beginnings as the ‘intellectual arm of the women's movement’. It argues that the complex story of Women's Studies has been marked by both ambiguity and uncertainty as well as sustained political commitment in the face of both institutional opposition and feminist ambivalence about Women's Studies as a field of scholarship. The development of Women's Studies occurs through crucial shifts in the theoretical paradigms of feminism and the political preoccupations of the women's movement. These shifts have both deconstructed the founding premises of feminist theory and generated a greater depth to feminist thinking and research. These challenges to Women's Studies have paralleled a different set of problems arising from the increasingly market-oriented direction pursued throughout the tertiary education sector. In spite of these difficulties Women's Studies continues to survive and constitutes an important and contested site of contemporary feminist thought.