Non-Heart-Beating Organ Donation: A Defense of the Required Determination of Death

The family of a patient who is unconscious and respirator-dependent has made a decision to discontinue medical treatment. The patient had signed a donor card. The family wants to respect this decision, and agrees to non-heart-beating organ donation. Consequently, as the patient is weaned from the ventilator, he is prepped for organ explantation. Two minutes after the patient goes into cardiac arrest, he is declared dead and the transplant team arrives to begin organ procurement. At the time retrieval begins, it is not certain that the patient's brain is dead or that cardiac function cannot be restored. Procurement follows uneventfully, and two transplantable kidneys are retrieved .     

Evaluation of Commercial Kits for Dual Extraction of DNA and RNA from Human Body Fluids, ,

STR typing of DNA evidence can identify the donor with a high power of discrimination but cannot identify the tissue origin of a body‐fluid stain. Using RNA to attribute a crime scene stain to a particular tissue may aid in reconstruction efforts. With blood from 10 donors, four DNA and RNA coextraction kits were evaluated by measuring yields and STR and mRNA profiles. T tests indicated some significant differences in kit performance. The Zymo Research ZR‐Duet^? kit performed best based on average DNA (41.4 ng) and mRNA (4.07 ng) yields and was the only kit to provide complete DNA/RNA profiles for all samples. The consistency of this kit was challenged by data from additional blood and saliva donors. Further testing is advised before a superior kit is unequivocally chosen. Stand‐alone DNA or RNA purification generally offers higher yield, but coextraction may still allow successful STR profiling and tissue source identification.     

The Development and Application of Random Match Probabilities to Firearm and Toolmark Identification

The field of firearms and toolmark analysis has encountered deep scrutiny of late, stemming from a handful of voices, primarily in the law and statistical communities. While strong scrutiny is a healthy and necessary part of any scientific endeavor, much of the current criticism leveled at firearm and toolmark analysis is, at best, misinformed and, at worst, punditry. One of the most persistent criticisms stems from the view that as the field lacks quantified random match probability data (or at least a firm statistical model) with which to calculate the probability of a false match, all expert testimony concerning firearm and toolmark identification or source attribution is unreliable and should be ruled inadmissible. However, this critique does not stem from the hard work of actually obtaining data and performing the scientific research required to support or reject current findings in the literature. Although there are sound reasons (described herein) why there is currently no unifying probabilistic model for the comparison of striated and impressed toolmarks as there is in the field of forensic DNA profiling, much statistical research has been, and continues to be, done to aid the criminal justice system. This research has thus far shown that error rate estimates for the field are very low, especially when compared to other forms of judicial error. The first purpose of this paper is to point out the logical fallacies in the arguments of a small group of pundits, who advocate a particular viewpoint but cloak it as fact and research. The second purpose is to give a balanced review of the literature regarding random match probability models and statistical applications that have been carried out in forensic firearm and toolmark analysis.     

Locard's Principle of Exchange,Dental Examination and Fragments of Skin

The transfer of materials between victim and perpetrator was first reported by Locard in the nineteenth century. While in recent years DNA testing has been very successful in matching biological material from crime scenes to perpetrators, the following cases demonstrate that other more time‐honored methods remain useful. Two cases of lethal assault are reported where the victims had bitten their assailants resulting in fragments of the perpetrators’ skin being wedged between their teeth which were discovered during post mortem oral examinations. As the fragments were able to be matched to injuries in the perpetrators, identification was established prior to confirmatory DNA testing. In case 1 a criminal conviction for manslaughter resulted, and in case 2 the identity of the assailant was confirmed. Examination of a properly exposed and illuminated oral cavity may provide useful evidence in assault cases. These cases represent an unusual dental variant of Locard's principle.     

Sobering Up on the Streets: Homeless Men in Alcoholics Anonymous

An exploratory, qualitative examination of homeless, recovering alcoholic men in a Twelve-Step program shows the ways these men adapt tools of sobriety to match their needs. Using semi-structured interviews, the experiences of these men were evaluated in order to find out how they stay sober without a formal place to live. Based on the narrative histories, three varieties of adaptations to the conventional Alcoholics Anonymous program are discussed: excessive twelfth-stepping, a mélange of religious principles, and unrealistic ideals. Implications for treatment and directions for future research are discussed.     

参与和可持续发展:公民、共同体与组织的参与模式

<正>在环境与发展的政策制定中公众参与的提升,一般被认为是政府对可持续发展治理的一个本质特征。例如,21世纪议程把"公众广泛地参与政策制定"作为"实现可持续发展的基本前提"(UN,1993:219)。经合组织也认为,考虑到"因为可持续发展目标的多样性和复杂性","精心设计的协商和参与过程在与政策推动可持续     

Learning under the cross: legal challenges to ‘cultural–religious symbolism’ in public schools

This article examines the nature and scope of the legal challenges mounted against religious symbolism in European public schools. It discusses religion in education and the relationship between Church and State in European societies. The European Court is defining what counts as a religious symbol through a secular lens and while the court upholds the right to hold a religious belief it qualifies this right to manifest belief in public. This article argues that the courts should be more accommodating in their approach towards the public manifestation of religious beliefs and traditions.