ORO. The Physical Developer replacement?

In the process of fingerprint development Physical Developer has been largely the method of choice on porous surfaces after coming into contact with wet environments. It is only recently that a new technique has been identified which could replace this standard technique. This study aims to build on previous research and expand knowledge regarding the technique. The study built on previous research and compared Physical Developer to Oil Red O, testing both on four paper types, while being placed in three different water types and an accelerant for various amounts of time. Marks were placed with both heavily ‘loaded’ sebaceous fingers and ‘normal’ un-washed fingers. Results show that Oil Red O consistently produced clearer more detailed marks from the ‘loaded’ fingers, but neither technique proved to work better on the ‘normal’ marks. Neither technique developed any prints from the accelerant.     

Explaining Dosage Diffusion During Hot Spot Patrols: An Application of Optimal Foraging Theory to Police Officer Behavior

Drawing from the concepts of optimal foraging theory, this paper presents and tests the assumptions of a foraging theory of police behavior during hot spots patrols. The theory explains why, over time, officers involved in hot spots policing interventions would leave the hot spots they are assigned to police and begin working within other locations. We test what factors influence the amounts of activity that officers undertake outside of their assigned hot spots and at nearby streets using data gathered as part of the Philadelphia Foot Patrol Experiment. Officers performed more activity outside of their beats as the experiment progressed. Several theoretically relevant variables predict the level of activity that officers perform outside their beats, including the size of the target area and the amounts of crime occurring within and outside of the target area. “Dosage diffusion” might be one reason why hot spot interventions have diminishing effects over time. From an optimal foraging theory perspective, hot spots requiring police officers to constrain their actions to pre-defined areas can be perceived as counter-intuitive by the officers, especially over extended periods of time. The results of this study support the suggestion that hot spots patrols should be short-term and randomly rotated across hot spots.     

The Challenges of Contracting and Accountability Across the Federal System: From Ambulances to Space Shuttles

This article focuses on two questions related lo governmentcontracting and accountability. How are key components of contractingsimilar or different for city, state, and federal governmentsin the United States? To what extent do the three levels ofgovernment share the widely recognized challenges of contractdesign and contract management? To address these questions,we compared and contrasted six contracting cases, two each forlocal, state, and the federal governments. We found that forall governments in the U.S. federal system, the public managementfunctions of contracting are remarkably similar, and that contractmanagement and the achievement of accountability are "weak links"in the contracting process. Our findings do not support thehypothesis that contract management is more effective in localgovernment relative to state and federal governments.     

Motives for suicide--a study of Australian suicide notes

Analysis of a large sample of suicide notes from 262 suicides in Australia found that men less often had escape from pain as a motive for their suicides and more often had love/romantic problems. The suicides of older persons were more often motivated by escape from pain and less often had love/romantic problems.     

Quantitative analysis of multiple illicit drugs in preserved oral fluid by solid-phase extraction and liquid chromatography–tandem mass spectrometry

We present a validated method for the simultaneous analysis of basic drugs which comprises a sample clean-up step, using mixed-mode solid-phase extraction (SPE), followed by LC–MS/MS analysis. Deuterated analogues for all of the analytes of interest were used for quantitation. The applied HPLC gradient ensured the elution of all the drugs examined within 14 min and produced chromatographic peaks of acceptable symmetry. Selectivity of the method was achieved by a combination of retention time, and two precursor-product ion transitions for the non-deuterated analogues. Oral fluid was collected with the Intercept^®, a FDA approved sampling device that is used on a large scale in the US for workplace drug testing. However, this collection system contains some ingredients (stabilizers and preservatives) that can cause substantial interferences, e.g. ion suppression or enhancement during LC–MS/MS analysis, in the absence of suitable sample pre-treatment. The use of the SPE was demonstrated to be highly effective and led to significant decreases in the interferences. Extraction was found to be both reproducible and efficient with recoveries >76% for all of the analytes. Furthermore, the processed samples were demonstrated to be stable for 48 h, except for cocaine and benzoylecgonine, where a slight negative trend was observed, but did not compromise the quantitation. In all cases the method was linear over the range investigated (2–200 μg/L) with an excellent intra-assay and inter-assay precision (coefficients of variation <10% in most cases) for QC samples spiked at a concentration of 4, 12 and 100 μg/L. Limits of quantitation were estimated to be at 2 μg/L with limits of detection ranging from 0.2 to 0.5 μg/L, which meets the requirements of SAMHSA for oral fluid testing in the workplace. The method was subsequently applied to the analysis of Intercept^® samples collected at the roadside by the police, and to determine MDMA and MDA levels in oral fluid samples from a controlled study.     

Correlation of Delta9-tetrahydrocannabinol concentrations determined by LC-MS-MS in oral fluid and plasma from impaired drivers and evaluation of the on-site Dräger DrugTest

Oral fluid (collected with the Intercept((R)) device) and plasma samples were obtained from 139 individuals suspected of driving under the influence of drugs and analyzed for Delta(9)-tetrahydrocannabinol (THC), the major psychoactive constituent of cannabis, using a validated quantitative LC-MS-MS method. The first aim of the study was to investigate the correlation between the analytical data obtained in the plasma and oral fluid samples, to evaluate the use of oral fluid as a 'predictor' of actual cannabis influence. The results of the study indicated a good accuracy when comparing THC detection in oral fluid and plasma (84.9-95.7% depending on the cut-off used for plasma analysis). ROC curve analysis was subsequently used to determine the optimal cut-off value for THC in oral fluid with plasma as reference sample, in order to 'predict' a positive plasma result for THC. When using the LOQ of the method for plasma (0.5 ng/mL), the optimal cut-off was 1.2 ng/mL THC in oral fluid (sensitivity, 94.7%; specificity, 92.0%). When using the legal cut-off in Belgium for driving under the influence in plasma (2 ng/mL), an optimal cut-off value of 5.2 ng/mL THC in oral fluid (sensitivity, 91.6%; specificity, 88.6%) was observed. In the second part of the study, the performance of the on-site Dr?ger DrugTest for the screening of THC in oral fluid during roadside controls was assessed by comparison with the corresponding LC-MS-MS results in plasma and oral fluid. Since the accuracy was always less than 66%, we do not recommend this Dr?ger DrugTest system for the on-site screening of THC in oral fluid.