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For street samples suspected of containing the phosphodiesterase-5 inhibitors sildenafil (Viagra(?)) and/or vardenafil (Levitra(?)), including powders or adulterated herbal supplements, a chemical analysis is needed to provide confirmatory identification of these illegally procured substances. Sildenafil and vardenafil are structurally similar and it is difficult to differentiate between them, as previous mass spectrometric studies have shown the two drugs to produce similar fragmentation patterns. The use of tandem mass spectrometry can produce confirmatory data, but the technique requires a high level of technical expertise. We have developed an electrospray ionization-liquid chromatography-mass spectrometry (ESI-LC-MS) method that allows differentiation between these two structurally similar molecules via in-source fragmentation in combination with an ion trap mass spectrometer. A very stable gas phase ion is formed during in-source fragmentation of vardenafil; the combination of the stability of this ion and the longer residence time for the ion in the ion trap results in a very strong signal. This feature results in a method that can provide clear differentiation between sildenafil and vardenafil while at the same time requiring less expertise from the routine analyst to confirm the presence or absence of the two compounds.  相似文献   
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This paper examines the tension between the mainstream belief in international law as a source of objectivity distinct from politics and its new stream critics that question the validity of such a distinction. It is argued that, as a type of language, international law is not distinct from politics as a function of objectivity, but rather by the fact that it serves the international community’s thymos. The phenomena of global administrative law and NATO’s use of force in Kosovo are analyzed as examples of how the thymos drives international law. Building on feminist theories of international law, the article sets forth a vision of international law as the primary communicative device for the international community’s thymos.  相似文献   
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McDonald  Jared 《Political Behavior》2021,43(4):1371-1394

Although prior research establishes the important effect perceptions of compassion have on vote choice, no systematic research examines why some candidates are perceived as more caring than others. In an era where television and social media put candidates’ personalities front and center, the lack of research on this topic is problematic. In this article, I explain why voters view some candidates as more caring than others. I argue that voters view politicians as compassionate when there is a commonality to link them. A commonality demonstrates an empathetic connection, or the ability to understand another’s feelings. This, in turn, convinces voters that the politician is sympathetic, or willing to do something to help. Without an empathetic connection, claims of sympathy by politicians will be viewed with greater levels of skepticism. I generate a classification system for the sources of commonality that link voters with politicians, including shared experiences, shared emotions, and shared identities. Using three survey experiments, I show how candidates can build empathic bonds with voters and better their chances of election.

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