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Correlation between plasma and bone marrow tricyclic antidepressants has not been studied before. Two groups of rabbits were given 10 and 20 mg of desipramine/kg body weight, respectively. Desipramine was administered to the animals once daily by mouth for 5 days. On the fifth day the animals were sacrificed and blood and bone marrow samples were collected and analyzed using a high performance liquid chromatographic (HPLC) method. Data showed that a correlation exists between bone marrow and blood desipramine. The bone marrow desipramine concentration increased as its blood levels increased. The average ratio of bone marrow to blood desipramine +/- S.D. (standard deviation) in both dosage groups was 37.2 +/- 4.46 with a range of 30.99-44.82. This investigation is promising and shows that bone marrow could be used as an alternative tissue in the absence of a suitable blood sample. 相似文献
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The Department of Defense has taken steps in recent years to improve outcomes for victims of domestic violence who reside on military installations. In 2000, the Defense Task Force on Domestic Violence was established, a military‐civilian group of experts charged with improving the military's effectiveness in addressing domestic violence in the Armed Forces in a variety of areas including offender accountability, coordination between military and civilian communities, and changing the military climate around domestic violence. This article will provide an overview of the Task Force, its work during the past three years, and its recommendations. 相似文献
37.
Recent major shifts in US military thinking, creating a new low-intensity conflict (LIC) doctrine, have resulted already in significant changes in organization, mission definition, force structure and budgetary allocation. These changes have come about because American leadership recognizes that the process of deindustrialization has produced a vulnerable, highly integrated and interdependent global economic system. This system of economic rationalization is susceptible to anti-western disruptions because of the instability produced by rapid social change, a consequence of the competition from the newly industrialized nations. LIC capability is viewed as a necessary means for dealing with disruptions. 相似文献
38.
Jeffrey Scott Mclllwain 《Trends in Organized Crime》2005,8(4):15-39
This article seeks to understand the processes by which the crime of intellectual property theft is organized, with specific
attention given to film piracy. It seeks to identify the structure and function of the criminal enterprises engaged in this
crime and assess the degree to which organized crime is involved with film piracy. An analysis of available sources reveals
that general conclusions about the relationship of organized crime to film piracy results from a lack of useable and verifiable
information in media, government, and industry sources. In the absence of independent, substantive analysis, anecdote and
industry interests currently drive public policies and legal developments created to address the role of organized crime in
film piracy. In the United States and across the globe, seizures, criminal indictments, civil actions, and public awareness
are up considerably. Whether or not these advances can be maintained in the face of technological advances, the evolution
of industry economic structures, and consumer indifference to the stigma of intellectual property theft and concern at industry
response to such theft remains to be seen. Specific recommendations for future research are offered.
The author would like to thank the International Center of the National Institute of Justice for soliciting funding this research
through a grant, Intellectual Property and Organized Crime. He also Thanks Jay S. Albanese and his the anonymous reviewers
of this work for their helpful comments and criticisms. This article only reflects the findings of the author, not the National
Institute of Justice, Dr. Albanese or the reviewers. 相似文献
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On the one hand the following case demonstrates the problems of finding a dead body in the bathroom and on the other hand the importance of postmortem x-ray examinations. The corpse of an 65-year-old woman was discovered in her bath tub. At the body's feet there was a hair dryer. Investigations concerning murder were negative, circumstances appeared to be unsuspicious. That was why a postmortem examination was not performed. -4 years later murder had to be considered. After manual strangling the deceased and the hair dryer were layed into the bath tub. The corpse was exhumed and taken to a forensic autopsy. It was found that the hyoid bone and the superior horn of the thyroid cartilage were both fractured on the right. Damages caused by the preparation itself were excluded by using serial roentgenographs. These observations in combination with histological findings and the results of further investigations convincingly supported the suspicion of strangling by hand. 相似文献