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141.
A transaction-based approach to policy intervention is presented. The approach overcomes a number of weaknesses in current approaches to policy intervention. The approach involves three main conceptual elements: transactions, transaction governance mechanisms, and governance principles. The transaction is taken to be the basic unit of analysis. Profiles of transactions vary along a number of transaction dimensions. Transaction governance mechanisms - such as, for example, government service, regulation, contracts, vouchers, markets, taxes, and self-service - are each suitable for governing transactions having particular profiles. A mechanism will fail when used to govern transactions not fitting the profile. Governance principles are criteria or expectations - for example, efficiency, justice and liberty - used to judge how well a mechanism fulfills or achieves important societal goals. Specific choices of governance mechanisms (from the set that are technically feasible) therefore should be made according to how well they satisfy these governance principles. Public high school education is used as an example to illustrate the approach. A number of conclusions are offered.This is a revised version of a paper presented at the Annual Meeting of the American Society for Public Administration Portland, Oregon, April, 1988.  相似文献   
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Judicial decisions are one element in the erosion of local government budgetary discretion. For example, litigation concerning constitutional rights forces local government officials to allocate resources toward the rights-based population. While rights-based allocation decisions may narrow the budgetary discretion of public officials, some managers may, paradoxically, be "better-off"—defined as the ability to protect and defend their budgets — when discretion is reduced. This thesis is tested through a case study of jail overcrowding litigation in a county government.  相似文献   
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B. Reviews     
THE CAMBRIDGE HISTORY OF ARABIC LITERATURE. Volume 1: Arabic Literature to the End of the Unayyad Period. Edited by A.F.L. Beeston, T.M.Johnstone, R.B.Serjeant and G.R.Smith, pp.xvi, 547. Cambridge University Press, 1983. £37.95.

AL‐MAQRIZI'S “BOOK OF CONTENTION AND STRIFE CONCERNING THE RELATIONS BETWEEN THE BANU UMAYYA AND THE BANU HASHIM”. Translated into English, with an introduction and commentary by C.E.Bosworth. (Journal of Semitic Studies, Monograph No.3), Manchester, Department of Near Eastern Studies, University of Manchester, 1980. pp.157.

ARABIC CULTURE THROUGH ITS LANGUAGE AND LITERATURE. By M.H. Bakalla. London, Kegan Paul International, 1984. pp.371, 51, plates, maps.

ARABIC LINGUISTICS: AN INTRODUCTION AND BIBLIOGRAPHY. By M.H. Bakalla. London, Mansell, 1983. pp.742.

LA RELATION DE THOMAS PELLOW: UNE LECTURE DU MAROC AU 18e SIÈCLE. By Magali Morsy. (Synthèse No.12), Paris, Editions Recherche sur les Civilisations, 1983. pp.254, 17pl. FF.129.

ESPANA Y EL NORTE DE AFRICA: EL PROTECTORADO DE MARRUECOS (1912–56). By Victor Morales Lezcano. Madrid, Universidad Nacional de Educacion a Distancia, 1984. pp.249. Photos., maps, diagrams. 600.00 ptas.

EGYPT AND THE PALESTINE QUESTION 1936–1945. By Thomas Mayer. Berlin, Klaus Schwarz Verlag, 1983. pp.391 (paperback).

SUDAN. By M.W.Daly. (World Bibliographical Series, Vol.40.) Oxford (UK) & Santa Barbara (USA), Clio Press, 1983. pp.xvi, 176, 1 map. £19.50.

THE OTHER FACE OF OPEC: FINANCIAL ASSISTANCE TO THE THIRD WORLD. ENERGY RESOURCES AND POLICIES OF THE MIDDLE EAST AND NORTH AFRICA. By Ibrahim F.I. Shihata. London, Longman, 1982. pp.281 (paperback).

DEVELOPING EDUCATION SYSTEMS IN THE OIL STATES OF ARABIA: CONFLICTS OF PURPOSE AND FOCUS. By J.S.Birks and J.A.Rimmer. (Occasional Papers Series, No.21: Manpower and Migration Series, no.3). University of Durham, Centre for Middle Eastern and Islamic Studies, 1984. pp.33. E2.50.

BIBLIOGRAPHICAL GUIDE TO IRAN: THE MIDDLE EAST LIBRARY COMMITTEE GUIDE. Edited by L.P.Elwell‐Sutton. Sussex, The Harvester Press/New Jersey, Barnes & Noble Books, 1984. pp.462.

ARABISCHE UND PERSISCHE PRIVATURKUNDEN DES 12. UND 13. JAHRHUNDERTS AUS ARDABIL (ASERBEIDSCHAN). By Monika Gronke. (Islamkundliche Untersuchungen, Bd 72), Berlin, Klaus Schwarz Verlag, 182. pp.555.

MYSTICISM AND DISSENT: SOCIORELIGIOUS THOUGHT IN QAJAR IRAN. By Mangol Bayat. Syracuse, N.Y., Syracuse U.P., 1982. pp.xvii, 228. $25.00.

SOCIAL DISINTEGRATION AND POPULAR RESISTANCE IN THE OTTOMAN EMPIRE 1881–1908: REACTIONS TO EUROPEAN ECONOMIC PENETRATION. By Donald Quataert. New York, Columbia U.P., 1983. pp.xxii, 205. $45.50.  相似文献   

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Validation of a 16-locus fluorescent multiplex system   总被引:24,自引:0,他引:24  
STR multiplexes have been indispensable for the efficient genotyping of forensic samples. The PowerPlex 16 System contains the coreCODIS loci, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, CSF1PO, FGA, THOI, TPOX, vWA, the sex determinant locus, amelogenin, and two pentanucleotide STR loci, Penta D and Penta E. This multiplex satisfies the locus requirements for most national databases and is the most efficient currently available system due to its single PCR amplification. To provide the groundwork for judicial acceptance, including the publication of primer sequences, and to evaluate laboratory-to-laboratory variation, a developmental validation for casework on this commercially available system was performed in 24 laboratories and produced the following conclusions. Amplification was reliable on a variety of thermal cyclers and product could be analyzed on either an ABI PRISM 310 Genetic Analyzer or an ABI PRISM 377 DNA Sequencer. Genotyping using single source samples was consistent between 0.25 and 2 ng of input DNA template with a few laboratories obtaining complete genotypes at 0.0625 ng. However, heterozygote allele imbalance (<60% peak height balance) caused by stochastic effects was observed at a rate of 13% with 0.125 ng DNA and 22% at 0.0625 ng DNA. Mixture analyses were done using a total of 1 ng of DNA template. Most alleles were detected in mixtures of 4 to 1 and some minor alleles were detected in mixtures of 19 to 1. Optimum amplification cycle number was dependent on the sensitivity of the detection instrument used and could also be adjusted to accommodate larger amounts of DNA on solid supports such as FTA paper. Reaction conditions including volume, annealing temperature, and concentrations of primer, AmpliTaq Gold, and magnesium were shown to be optimal yet robust enough to withstand moderate variations without affecting genotype analysis. Environmental, matrix and standard source analyses revealed an ability to obtain complete genotypes in all sample types except those exposed to 80 degrees C for 12-48 days. Finally, comparison of genotype results from the PowerPlex 16 System with other commercially available systems on non-probative reference and forensic samples showed consistent results.  相似文献   
150.
Mitochondrial DNA analysis of a maggot crop can identify the corpse a maggot has been feeding on. Analysis of the crop could be useful in a criminal investigation if maggots are found at a suspected crime scene in the absence of a body, or if there is a question of whether a maggot used in postmortem interval estimations moved onto the corpse from another food source. Such analysis can also resolve a chain of custody dispute if it has been suggested that larval samples have been switched. When recovering DNA from a maggot crop, the analyst must be careful to avoid external contamination. We investigated the effects of three simple wash methods developed to reduce external contamination. Maggots raised on pig liver and intentionally contaminated with cow blood were washed using water, 20% bleach, or a solution containing the enzyme DNase. Only washing the maggots in 20% bleach reduced the amount of vertebrate DNA amplified from the maggots' exteriors. No wash method affected the ability to recover DNA from the maggot crops.  相似文献   
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