Socio‐economic Considerations in Biosafety and Biotechnology Decision Making: The Cartagena Protocol and National Biosafety Frameworks

Article 26.1 of the Cartagena Protocol on Biosafety left open the possibility for member countries to include in their biosafety regulatory processes the assessment of socio‐economic considerations. Countries may also decide to include such assessments as part of their national legislation or regulations for the approval and deliberate release into the environment of genetically engineered technologies. Countries are debating if and how to implement assessment of socio‐economic considerations. This paper contributes to the ongoing policy dialogue by discussing issues related to socio‐economic assessment including scope, timing, inclusion modalities, methods, decision‐making rules and standards, and the integration of socio‐economic assessments in biosafety and/or biotechnology approval processes. This paper also discusses the implications of such inclusion for technology flows and public and private sector R&D. If inclusion is not done properly, it may negatively impact technology flows especially from the public sector and render an unworkable biosafety system.     

Measuring New Public Management and Governance in Political Debate

New Public Management (NPM) recently has been compared and contrasted with public governance (PG) to illustrate shifts in conceptions of public administrations and in reform agendas. The authors develop measures to capture the relevance of NPM and PG in textual discourse and investigate the extent to which they have entered the political debate. Content analysis of electoral programs for the 2005 Italian regional elections reveals that even in this legalistic country, considerable attention was paid to both NPM and PG issues. An important explanatory variable in preference for NPM or PG is party ideology, highlighting often‐ignored within‐country dynamics. Furthermore, the authors show how a methodological approach adapted from mainly political science and business research can be exploited in the field of public administration.     

Permanent teeth development in a Spanish sample. Application to dental age estimation

The purpose of this study is to clarify the chronology of different stages of dental development, according to Demirjian, in a sample of Spanish children, which will enable us to build a database that will be used as a reference in regard to the dental development of individuals of our socio-geographic environment. In the same studied sample, a calculation of the dental age according to Demirjian was carried out. This study was conducted in a final sample consisting of 1010 orthopantograms, corresponding to Spanish children (485 boys and 525 girls) ages 2-16. Comparing the age of onset of the different stages among the children, evidence was found that girls had an earlier general development than boys. These differences were only statistically significant in teeth and concrete stages. The canine teeth revealed greater gender dimorphism, with significant differences in all stages compared with the upper canines. The method proposed by Demirjian for dental age calculation resulted in a significant overestimation of dental age in relation to the chronological age in boys (average of 0.87 years) and girls (average of 0.55 years). Data from this study may be used as reference for dental maturity, as well as a standard for estimating age in Spanish children.     

How is Anxiety Involved in the Longitudinal Relationship between Brooding Rumination and Depressive Symptoms in Adolescents?

A growing body of research supports the application of Response Styles Theory to adolescent populations. Although the essential dynamic, namely that rumination increases the incidence of depressive symptoms, has been demonstrated among adolescents, a number of important empirical questions remain, such as: what are the gender differences and developmental trends for brooding and reflective rumination?; does a reciprocal relationship exist between brooding or reflective rumination, on the one hand, and depressive symptoms and anxiety, on the other hand, over time? and how do additional variables (i.e., anxiety) impact upon the rumination-depressive symptoms relationship? In this study, self-reported levels of rumination (both brooding and reflective), and anxious and depressive symptoms were measured longitudinally across 4 months in a sample of 976 community adolescents (46 % females), aged 11–16 years old. Mean group differences showed that female adolescents reported engaging in more brooding rumination than male adolescents beginning at 13 years of age. A reciprocal brooding rumination to depressive symptoms relationship and a reciprocal brooding rumination to anxiety relationship were found over time, and they did not differ for boys and girls. We tested the possibility that anxious symptoms would function as a third variable, but the obtained model showed that brooding rumination and anxiety both contributed unique variance in predicting changes in depressive symptoms over time.     

The legal framework of private universities in Spain

The setting up of Universities in Spain is considered to be part of the fundamental right to establish private educational institutions. For a long time there have only existed Church Universities alongside Public Universities, and these have had their legal basis in Agreements between Spain and the Vatican. As of 1991 there has been an on-going process of setting up purely private Universities, to the point that there are now eleven besides the Church Universities. This article examines their legal framework from the point of view of their organisation, the system governing their teaching staff and their effective autonomy with regard to the Public Authorities. This revised version was published online in July 2006 with corrections to the Cover Date.     

Acute flurazepam intoxication: a case report

A fatality due to ingestion of flurazepam is reported. Flurazepam is a benzodiazepine, a widely prescribed hypnotic drug for use in sleep disorders. There are only few documented reports of the disposition of flurazepam in deaths due to overdose. A 68-year-old woman was found deceased at home with no evidence of trauma or asphyxia. Toxicologic analyses were performed and drug levels measured by means of gas chromatography coupled to mass spectrometry. The flurazepam concentration in each specimen was as follows: heart blood 2.8 microg/mL, bile 323 microg/mL, and urine 172 microg/mL. Presence of flurazepam into gastric content was observed too. Based on the autopsy findings, patient history, and toxicologic results, the cause of death was determined to be acute intoxication of flurazepam and the manner, suicide.