Synthetic cannabinoids in "spice-like" herbal blends: First appearance of JWH-307 and recurrence of JWH-018 on the German market

Herbal smoking blends, available on the German market were analyzed and several known synthetic cannabinoids were identified (JWH-122 and JWH-018). In addition, we isolated a new active ingredient by silica gel column chromatography and elucidated the structure by nuclear magnetic resonance (NMR) methods. The compound was identified as JWH-307, a synthetic cannabinoid of the phenyl-pyrrole subclass with known in vitro binding affinities for cannabinoid receptors. To date, this is the first appearance of this subclass of cannabimimetics in such products. JWH-307 has been further characterized by gas chromatography accurate mass spectrometry (GC-HRMS), electrospray tandem mass spectrometry (ESI-MS/MS), ultraviolet (UV) and infrared (IR) spectroscopy. JWH-018 was among the first compounds banned by many countries world-wide including Germany. The identification of JWH-018 was striking, since this is the first report where JWH-018 recurred on the German market thus violating existing laws. A generic method was established to quantify synthetic cannabinoids in herbal smoking blends. Quantification was achieved using an isotopically labeled standard (JWH-018-D(3)). JWH-018 was found at a level of 150mg/g while JWH-122 and JWH-307 occurred as a mixture at a total level of 232mg/g.     

Rechtliche Einordnung von Grünbrücken bei Aus- und Neubauten sowie bestehenden Bundesfernstraßen

Natur und Recht - Angesichts der enormen Zerschneidungswirkung von Bundesfernstraßen werden Grünbrücken in der Bundesrepublik vermehrt errichtet, sodass sich die Frage der...     

The spaces of intervention for Mali and Guinea-Bissau

ABSTRACT

This article focuses on interventions by the African Union and the Economic Community of West African States in Guinea-Bissau and Mali. In the literature, these are often approached in a ‘top-down’ manner, focusing on formal institutions, not accounting for the complex dynamics in and around conflict intervention. This article argues that adopting space as an analytical lens allows new ways to address these issues. It highlights how interventions by different actors and their interactions are influenced by spatial perceptions and framings, which result in the making of different ‘spaces of intervention’ through different practices. The two described here, ‘scaling’ and ‘establishing reach’, enable strategic and continuous formation and negotiation of spaces for action, according to actors’ needs and interests. Thus, shedding light on specific actors and their practices, the article contributes to a better understanding of the complex dynamics in conflict intervention in West Africa.     

Von Rentnern und Rentiers

Ohne Zusammenfassung     

Aggregation technology of common goods and its strategic consequences: Global warming,biodiversity, and siting conflicts

Abstract. The analysis of common goods needs to look closely at the characteristics of the goods in question and the social situations in which they are provided. Different characteristics lead to different strategic constellations and therefore to different opportunities for institutional solutions to the problems of provision. Basic differences in strategic constellations can be shown clearly by employing matrix games. In this paper a particular attribute of common goods, their aggregation technology, is systematically analyzed. Three variations in this dimension are exemplified by cases from environmental policy. It becomes clear that the analysis of one specific attribute of a good will seldom suffice to predict empirical behavior. Nevertheless, rigorous game theoretic analysis provides valuable insights into the links between the characteristics of common goods and the need for institutions.     

Aggregation technology of common goods and its strategic consequences: Global warming, biodiversity, and siting conflicts

The analysis of common goods needs to look closely at the characteristics of the goods in question and the social situations in which they are provided. Different characteristics lead to different strategic constellations and therefore to different opportunities for institutional solutions to the problems of provision. Basic differences in strategic constellations can be shown clearly by employing matrix games. In this paper a particular attribute of common goods, their aggregation technology, is systematically analyzed. Three variations in this dimension are exemplified by cases from environmental policy. It becomes clear that the analysis of one specific attribute of a good will seldom suffice to predict empirical behavior. Nevertheless, rigorous game theoretic analysis provides valuable insights into the links between the characteristics of common goods and the need for institutions.