GHB can be produced either as a pre- or postmortem artifact. The authors describe two cases in which GHB was detected and discuss the problem of determining the role of GHB in each case. In both cases, NaF-preserved blood and urine were analyzed using gas chromatography. The first decedent, a known methamphetamine abuser, had GHB concentrations similar to those observed with subanesthetic doses (femoral blood, 159 microg/ml; urine, 1100 microg/ml). Myocardial fibrosis, in the pattern associated with stimulant abuse, was also evident. The second decedent had a normal heart but higher concentrations of GHB (femoral blood, 1.4 mg/ml; right heart, 1.1 mg/ml; urine, 6.0 mg/ml). Blood cocaine and MDMA levels were 420 and 730 ng/ml, respectively. Both decedents had been drinking and were in a postabsorptive state, with blood to vitreous ratios of less than 0.90. If NaF is not used as a preservative, GHB is produced as an artifact. Therefore, the mere demonstration of GHB does not prove causality or even necessarily that GHB was ingested. Blood and urine GHB concentrations in case 1 can be produced by a therapeutic dose of 100 mg, and myocardial fibrosis may have had more to do with the cause of death than GHB. The history in case 2 is consistent with the substantial GHB ingestion, but other drugs, including ethanol, were also detected. Ethanol interferes with GHB metabolism, preventing GHB breakdown, raising blood concentrations, and making respiratory arrest more likely. Combined investigational, autopsy, and toxicology data suggest that GHB was the cause of death in case 2 but not case 1. Given the recent discovery that postmortem GHB production occurs even in stored antemortem blood samples (provided they were preserved with citrate) and the earlier observations that de novo GHB production in urine does not occur, it is unwise to draw any inferences about causality unless (1) blood and urine are both analyzed and found to be elevated; (2) blood is collected in NaF-containing tubes; and (3) a detailed case history is obtained. 相似文献
The literature on democratization tends to neglect the question of decentralization. The case of the Hong Kong Special Administrative Region (HKSAR) of the People's Republic of China shows that there can be partial democratization without decentralization. Democratization in Hong Kong took place in the mid‐1980s and 1990s, when more directly elected seats were introduced to political institutions at the territorial, municipal and district levels. However, democratization has not been accompanied by an attempt to decentralize administrative and political power to the institutions at the local level. These political institutions, including the Urban Council (UrbCo), Regional Council (RegCo) and District Boards remain relatively weak vis‐à‐vis the executive branch of the government. The recent attempt by the HKSAR government to abolish the UrbCo and RegCo represents a move toward centralization of administrative and political power. Moreover, District Boards remain consultative and politically powerless. It is the dynamic relationship between democratization and decentralization at which future research should be directed. 相似文献
i. Oman and Southeastern Arabia: A Bibliographic Survey. By Michael Owen Shannon. Boston, Mass., G.K.Hall & Co., 1978. pp.xvi, 165. $18.00.
ii. Türk Dili ve Edebiyati Ansiklopedisi:Devirler/Isimler/ Eserler/Terimler. Istanbul, Dergah Yayinlari, 1977. TL600 (for 2 vols.).
iii. Arab‐Israeli conflict: a historical, political, social and military bibliography. By Ronald M.De Vore. Oxford, Clio Press, 1976, pp.273. £10.45.
Conflict in the Middle East from October 1973 to July 1976: a selected bibliography. By Michael Rubner. Los Angeles, Center for the Study of Armament and Disarmament, California State University, 1977. pp.83. $3.00.
The Palestine Question: a select bibliography. Compiled from the holdings of the Dag Hammarskj?ld Library, United Nations. New York, United Nations, 1976. pp.63. £3.25 (Distributed in the U.K. by H.M.S.O.).
iv. Middle East Contemporary Survey: Volume I 1976–77.
Edited by Colin Legum. Tel Aviv, Shiloah Center for Middle Eastern and African Studies, University of Tel Aviv, and New York and London, Holmes and Meier, 1978. pp.xxiv, 684. £32.50.
v. The Modern Middle East: A Guide to Research Tools in the Social Sciences. By Reeva S.Simon. Boulder, Colorado, Westview Press, 1978. pp.xv, 283. £6.10.
vi. Gustav Meisels, Reference Literature to Arabic Studies, a bibliographical guide. Tel Aviv, University Publishing Projects Ltd., 1978. pp.xiv + 251.
vii. Saudi Arabia (World Bibliographical Series Vol.5).
Compiled by Frank A.Clements. Oxford and Santa Barbara, Clio Press, 1979. pp.xiv, 195. £16.75.
viii. The Records of the British Residency and Agencies in the Persian Gulf. IOR R/15. (India Office Records: Guides to Archive Groups). By Penelope Tuson. London, India Office Library and Records, 1979. pp.xix, 188. Pl.6. Index. £21.95.
ix. Modern Syria: An Introduction to the Literature. Compiled by C.H.Bleaney. Durham University, Centre for Middle Eastern and Islamic Studies (Occasional Papers Series, no.6). 1979. £4.00.
x. The Encyclopaedia of Islam. New Edition: Encyclopédie de 1'Islam. Nouvelle édition. Index to Volumes/aux [sic: read ‘des‘]Tomes I‐III. Compiled by/Établi par H.& J.D. Pearson. Edited by/Publié par E.van Donzel. Leiden, Brill/Paris, G.P.Maisonneuve & Larose S.A., 1979. pp.viii, 195. 60 guilders. 相似文献
i. Middle East and Islam: A Bibliographical Introduction (Bibliotheca Asiatica 15). Edited by Diana Grimwood‐Jones, for the Middle East Libraries Committee [MELCOM]. Revised and enlarged edition. Zug, Inter Documentation Company, 1979. pp. ix, 429.
ii. Middle East Studies and Libraries. A Felicitation Volume for Professor J.D. Pearson. Edited by B.C. Bloomfield. London, Mansell, 1980. pp. xi, 231.
iii. Cultures of the Islamic Near East: A Guide to Introductory Readings for the Non‐Specialist. By John W. Bagnole. Washington, D.C., America‐Mideast Educational & Training Services, Inc. (Occasional Paper, No. 4), 1978. pp. ii, 79. $4.00
iv. The Modern Arab Woman: A Bibliography. By Michelle Raccagni. Metuchen, N.J. & London, The Scarecrow Press, 1978, pp. x, 282. 相似文献
A study was undertaken to develop demographic, toxicologic, and pathological profiles of methamphetamine-related deaths. Anatomic and toxicologic findings in 413 deaths where methamphetamine was detected were compared with findings in a control group of 114 drug-free trauma victims. The number of cases per year did not change significantly over the course of the study. Mean age was 36.8 years, but 11% were over the age of 50. Decedents were overwhelmingly male (85.2%) and Caucasian (75%). Blood concentrations of methamphetamine and amphetamine were indistinguishable in cases where methamphetamine was related to the cause of death (MR) and cases where it was not (non-MR) (2.08 vs. 1.78 mg/L, p = 0.65, and 0.217 vs. 0.19 mg/L, p = 0.82). Coronary artery disease, ranging from minimal to severe multivessel, was identified in 79 of the 413 drug users, but in only six of the 114 drug-free controls (p = 0.0004), and MR decedents had enlarged hearts compared with controls. There were also ten cases of subarachnoid and intracranial hemorrhage in the MR group. Abnormalities of the liver (34%) and lungs (24.7%) were frequent. In 65% of these cases, death was due to accidental methamphetamine toxicity. In the remaining cases, methamphetamine was an incidental finding. We conclude that, in our jurisdiction, neither the rate of detection nor the number of methamphetamine deaths has increased significantly in the past 13 years. Decedents are almost all Caucasian males, and many were approaching middle-age. Methamphetamine use is strongly associated with coronary artery disease and with subarachnoid hemorrhage. 相似文献