Immunohistochemical quantification of pulmonary mast-cells and post-mortem blood dosages of tryptase and eosinophil cationic protein in 48 heroin-related deaths

Recent studies suggest that many fatal heroin overdoses are caused by anaphylactoid reaction. In the present study we measured tryptase and eosinophil cationic protein in post-mortem blood of 48 deaths after heroin injection. We also investigated the presence and pulmonary distribution of mast-cells using specific immunohistochemical antibody for tryptase and morphometric evaluation in those cases of heroin-related deaths. The data were compared with 44 subjects who died following head trauma and to 32 cases of fatal anaphylactic shock. In the heroin-related death cases, the measurements of serum tryptase levels and eosinophil cationic protein dosages resulted in particularly elevated concentrations compared with the trauma cases. Nevertheless, the data that our study supplies by immunohistochemical techniques indicate that when mast-cells count in the lung was determined, no definite pattern was obtained between fatal heroin overdose cases and the control groups. Furthermore, the wide range of morphine concentrations found in post-mortem blood samples suggest that the term ‘overdose’ is relative and does not sufficiently characterize death associated with heroin addiction. Our study confirms that elevated concentrations of serum tryptase are associated with many heroin-related deaths. At this moment to attribute the cause of these deaths to ‘heroin overdose’ ignores the likely causal contribution of other possible systemic reactions to the mechanism of death.     

Fatal footsteps: murder of undocumented border crossers in Maricopa County, Arizona

In the past 5 years, the mortality rate among undocumented workers in Arizona has increased steadily. In 1998-1999, the number of deaths among border crossers was 28. That number increased dramatically in 1999-2000 to 106 and has exceeded 200 in each of the past 2 years. In the past, many immigrant deaths occurred as a result of dehydration and exposure (1). More recently, a new trend has emerged, that is, death of border crossers at the hands of the persons ("coyotes") hired to lead them across the border to safety. In some cases, the smugglers attempt to extort additional money from the families by holding the victims hostage once they have crossed the border into the United States. If the families fail to pay, the hostage is killed. Rival gangs are also murdering one another over their human cargo. Nine recent cases illustrate this trend in Maricopa County. In each example, the victims were bound, shot (or in one instance stabbed) and dumped in a remote desert area. All of the decedents were linked to murder for extortion by the 'coyotes' or rival gang members.     

Exploring the relationships of women's sexual assault disclosure, social reactions, and problem drinking

The goal of this exploratory study was to examine correlates of sexual assault disclosure and social reactions in female victims with and without drinking problems. An ethnically diverse sample of sexual assault survivors was recruited from college, community, and mental health agencies. Ethnic minority women were less likely to disclose assault, and women with a greater number of traumatic life events disclosed assault more often. Although there were no differences in disclosure likelihood by drinking status; of those disclosing, problem drinkers told more support sources and received more negative and positive social reactions than nonproblem drinkers. Correlates of receiving negative social reactions were similar for normal and problem drinkers; however, negative social reactions to assault disclosure were related to more problem drinking for women with less frequent social interaction. Implications for future research and possible support interventions with problem-drinking victims are provided.     

Martyrs for Free Speech? Disentangling the Effects of Legal Prosecution of Anti-immigration Politicians on their Electoral Support

Political Behavior - Several anti-immigration politicians in Europe have been prosecuted for hate speech; some of these trials were highly mediatized. To what extent, and how, does hate speech...     

Philosophical Criminology and Complex Systems Science: Towards a Critical Theory of Justice

Chaos theory (or complex systems science, CSS) has made considerable inroads across a range of social science disciplines, including criminology. However, little has been done to assess the relevance of chaos theory for advancing a philosophical criminology. This task is significant because it tells us something about where, how, and why most modernist theories of crime are of limited utility when advancing the interests of justice and humanism in society. Accordingly, this article outlines the essential features of a philosophical criminology, including its commitments to ontology, epistemology, aesthetics, and ethics. Moreover, the contexts in which several key chaos theory principles such as iteration, sensitive dependence on initial conditions, bifurcations, attractors, fractal space, and dissipative structures function to promote a philosophical criminology are explored. A number of implications stemming from this analysis for purposes of critical theory building in law, crime, and justice studies are provisionally delineated.

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Angular Determination of Toolmarks Using a Computer‐Generated Virtual Tool

A blind study to determine whether virtual toolmarks created using a computer could be used to identify and characterize angle of incidence of physical toolmarks was conducted. Six sequentially manufactured screwdriver tips and one random screwdriver were used to create toolmarks at various angles. An apparatus controlled tool angle. Resultant toolmarks were randomly coded and sent to the researchers, who scanned both tips and toolmarks using an optical profilometer to obtain 3D topography data. Developed software was used to create virtual marks based on the tool topography data. Virtual marks generated at angles from 30 to 85° (5° increments) were compared to physical toolmarks using a statistical algorithm. Twenty of twenty toolmarks were correctly identified by the algorithm. On average, the algorithm misidentified the correct angle of incidence by ?6.12°. This study presents the results, their significance, and offers reasons for the average angular misidentification.     

The Applicability of the Lamendin Method to Skeletal Remains Buried for a 16-Year Period: A Cautionary Note

The Lamendin method is widely reported as one of the most reliable means of age estimation of skeletal remains, but very little is known concerning the influence of burial in soil. This study aimed at verifying the reliability of the Lamendin method on corpses buried for 16 years in a cemetery. The Lamendin and the Prince and Ubelaker methods were applied. In all age groups except the 40- to 49-year–olds, the error was higher in the buried sample. The age-at-death error ranged between 10.7 and 36.8 years for the Lamendin method (vs. the reported 7.3–18.9 years) and 9.5 and 35.7 for the Prince and Ubelaker one (vs. the original 5.2–32.6 years); in all age groups, the error is closer to that found on archeological populations. These results suggest caution in applying the Lamendin method to forensic cases of human remains buried even for a brief period under soil.