Drug and chemical related deaths: incidence in the State of Maryland--1975 to 1980

The incidence of drug and chemical related deaths was studied over a six-year period in the State of Maryland. Deaths were classified into the following categories: alcohol, carbon monoxide (CO), single drugs, multiple drugs, and narcotism. The last three categories were further subdivided as to the specific drugs or chemicals involved. Over the six-year period the number of alcohol and CO deaths remained steady, the number of barbiturate and propoxyphene deaths declined, while the number of tricyclic antidepressant drug deaths increased.     

Presidential prototypes

The American public expresses considerable consensus on those qualities of character and performance indispensable to a modern president. Contrary to expectations, however, such conceptions of an ideal president (or presidential prototypes) generally failed to provide standards by which actual presidential candidates were evaluated. Across five complementary tests, qualities that citizens thought important for an ideal president counted no more heavily in their evaluations of presidential hopefuls than did qualities thought less important—with one consistent and striking exception. Conceptions of an ideal president did set the standards by which the incumbent president was evaluated, and quite powerfully so. In the final section of the paper, we provide several interpretations of these results, suggest how public conceptions of an ideal president are acquired, and speculate about processes of presidential appraisal.     

Investigation of the short-time autolysis of rat hearts by means of SDS. Polyacrylamide gel electrophoresis and electron microscopy.

The short-time autolysis of hearts was regarded as a model of ischaemic heart failure. Therefore, isolated rat hearts were subjected to 30--120 min autolysis in a Locke solution at 37 degrees C. Electron microscopic examinations and myofibrillar preparations were made from the autolysed heart ventricles. The myofibrillar proteins were resolved by SDS-polyacrylamide gel electrophoresis. After 30 min autolysis the amount of a protein of 192,000 daltons greatly increased. At the same time on the electron micrographs the focal destruction of filament destruction on the A filament area and the mitochondrial structure altered too. After 60 min autolysis another protein of 36,400 daltons appeared. On the electron micrographs the focal desintegration of Z membranes and the focal destruction of I filaments can be observed. After 120 min autolysis further proteolytic products could not be detected by gel electrophoresis but on the electron micrographs the destruction of Z membranes and I filaments became more pronounced.