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排序方式: 共有216条查询结果,搜索用时 31 毫秒
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Stefania Turrina Giulia Filippini Luciana Caenazzo Domenico De Leo 《Forensic Science International: Genetics Supplement Series》2009,2(1):21-22
Short amplicon autosomal short tandem repeat (Mini-STR) assay has proved to be a highly useful tool in forensic applications, especially for highly degraded DNA samples that typically result in partial profiles and total loss of information from regular STR amplicons.In this study two new quadruplex systems were designed to get nuclear DNA profile from degraded forensic casework samples. In order to obtain PCR products less than 120 bp in size, primer pairs of eight STR markers, included in available commercially multiplex PCR kits, were redesigned and assembled in two PCR-multiplexes: D8S1179, D3S1358, TPOX, D16S539 and CSF1P0, TH01, D13S317, D5S818.After validation, these two Mini-STR quadruplex were employed in paternity testing case that involved DNA extraction from archival postmortem Bouin's fluid-fixed paraffin-embedded tissue where commercial kit yielded low success. The results obtained with the present Mini-STR PCR-multiplexes proved clearly demonstrating their usefulness in analyzing degraded DNA samples. 相似文献
164.
Saul M. Kassin Steven A. Drizin Thomas Grisso Gisli H. Gudjonsson Richard A. Leo Allison D. Redlich 《Law and human behavior》2010,34(1):3-38
Reviewing the literature on police-induced confessions, we identified suspect characteristics and interrogation tactics that
influence confessions and their effects on juries. We concluded with a call for the mandatory electronic recording of interrogations
and a consideration of other possible reforms. The preceding commentaries make important substantive points that can lead
us forward—on the effects of videotaping of interrogations on case dispositions; on the study of non-custodial methods, such
as the controversial Mr. Big technique; and on an analysis of why confessions, once withdrawn, elicit such intractable responses
compared to statements given by child and adult victims. Toward these ends, we hope that this issue provides a platform for
future research aimed at improving the diagnostic value of confession evidence. 相似文献
165.
The cause of mental disorders such as depression remains unknown. However, the idea that neurotransmitter imbalances cause
depression is vigorously promoted by pharmaceutical companies and the psychiatric profession at large. We examine media reports
referring to this chemical imbalance theory and ask reporters for evidence supporting their claims. We then report and critique
the scientific papers and other confirming evidence offered in response to our questions. Responses were received from multiple
sources, including practicing psychiatrists, clients, and a major pharmaceutical company. The evidence offered was not compelling,
and several of the cited sources flatly stated that the proposed theory of serotonin imbalance was known to be incorrect.
The media can play a positive role in mental health reporting by ensuring that the information reported is congruent with
the peer-reviewed scientific literature.
相似文献
Jonathan LeoEmail: |
166.
Leo H. Kahane 《Public Choice》2009,139(3-4):343-356
Using data for the 50 US states for presidential elections from 1972 to 2004 two theories for determining state voting outcomes are considered jointly: the ‘economy matters’ and ‘home grown-ness’ theories. Fixed-effects regressions show that measures of the ‘economy matters’ (real income, unemployment and a proxy for inflation) have the predicted effects on state voting patterns for presidential elections. The home grown theory receives mixed support. There is weak evidence that incumbent-party candidates garner greater support in their home states. There is strong support, however, for the proposition that incumbent-party candidates fare worse in the home state of rival-party candidates. 相似文献
167.
Abstract: This article argues that Section 23 of the Charter, litigation and judicial decisions have played key roles in expanding and homogenizing official minority‐lanpage education (omle ) policy outside Quebec. The importance of looking beyond Charter jurisprudence to the broader policy impact of litigation and judicial decisions is revealed. The Supreme Court'sMahé decision was particularly important in putting omle policy on the agenda and for providing Francophone groups with important legal, political and symbolic resources that were effectively exploited to generate policy change. Sommaire: Ce texte soutient que les litiges et la jurisprudence déoulant de l'article 23 de la Charte ont joué un rôle essentiel dam l'élargissement et l'uniformisation de la politique relative à l'enseignement dans la langue de la minorité en dehors du Quebec. Il révèle l'importance de voir au‐delè de la Charte quelles ont été les répercussions des litiges et de la jurisprudence sur la politique dans son ensemble. La dkision rendue par la Cour suprême dans l'affaire Mahé a été particulierement importante en mettant à l'ordre du jour la politique de l'enseignement dans la langue de la minorité et en offrant aux groupes francophones d'importantes ressources juridiques, politiques et symboliques dont ils ont effedivement su tirer parti pour engendrer une modification de la politique. 相似文献
168.
Jason R. Soble W. Alexander Alverson Jacob I. Phillips Edan A. Critchfield Chrystal Fullen Justin J. F. ORourke Johanna Messerly Jonathan M. Highsmith K. Chase Bailey Troy A. Webber Janice C. Marceaux 《Psychological injury and law》2020,13(1):44-56
Mirroring clinical guidelines, recent Performance Validity Test (PVT) research emphasizes using ≥ 2 criterion PVTs to optimally identify validity groups when validating/cross-validating PVTs; however, even with multiple measures, the effect of which specific PVTs are used as criterion measures remains incompletely explored. This study investigated the accuracy of varying two-PVT combinations for establishing validity status and how adding a third PVT or applying more liberal failure cut-scores affects overall false-positive (FP)/-negative (FN) rates. Clinically referred veterans (N = 114; 30% clinically identified as invalid) completing a six-PVT protocol as during their evaluation were included. Concordance rates were calculated across all possible two-and three-PVT combinations at conservative and liberal cutoffs. Two-PVT combinations classified 72–91% of valid (0–4% FPs) and 17–74% of invalid (0–40% FNs) cases, and three-PVT combinations classified 67–86% of valid (0–6% FPs) and 57–97% of invalid (0–24% FNs) at conservative cutoffs. Liberal cutoffs classified 53–86% of valid (0–15% FPs) and 39–82% of invalid (0–30% FNs) cases for two-PVT combinations and 46–75% of valid (3–27% FPs) and 60–97% of invalid (0–17% FNs) cases for three-PVT combinations. Irrespective of whether a two-or three-PVT combination or conservative/liberal cutoffs were used, many valid and invalid cases failed only one PVT (3–68%).Two-PVT combinations produced high FNs and were less accurate than three-PVTs for detecting invalid cases, though variable accuracy was found within both types of combinations based on the specific PVTs in the combination. Thus, both PVT quantity and quality are important for accurate validity classification in research studies to ensure reliability and replicability of findings. Applying more liberal cutoffs yielded increased sensitivity, but with generally higher FPs yielding problematic specificity, particularly for three-PVT combinations. 相似文献
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