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Darrell O. Ricke Ph.D. Philip Fremont‐Smith M.S. James Watkins B.S. Sara Stankiewicz M.S. Tara Boettcher B.S. Eric Schwoebel Ph.D. 《Journal of forensic sciences》2019,64(5):1468-1474
High‐throughput sequencing (HTS) of large panels of single nucleotide polymorphisms (SNPs) provides an alternative or complimentary approach to short tandem repeats (STRs) panels for the analysis of complex DNA mixture forensic samples. For STRs, methods to estimate individual contribution concentrations compare capillary electrophoresis peak heights, peak areas, or HTS allele read counts within a mixture. This article introduces three approaches (mean, median, and slope methods) for estimating individual DNA contributions to forensic mixtures for HTS/massively parallel sequencing (MPS) SNP panels. For SNPs, the major:minor allele ratios or counts, unique to each contributor, were compared to estimate contributor proportion within the mixture using the mean, median, and slope intercept for these alleles. The estimates for these three methods were typically within 5% of planned experimental contributions for defined mixtures. 相似文献
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Michael B. Bishku 《Nationalism and Ethnic Politics》2017,23(4):431-452
This article will examine the interactions of Armenians and Jews as well as shared and dissimilar experiences in the Ottoman Empire and the Republic of Turkey from the early 20th century to the present to compare how affinities and differences in political outlook have affected their relationship. It has been stated at times in academia, by politicians, and members of the press that the Armenian and Jewish Diasporas have had similar historical experiences mostly through hardships. Despite that being the case, this article will show that throughout their experiences as non-Muslim minorities in the Ottoman Empire and the Republic of Turkey Armenians and Jews have never developed any coordinated collaboration; instead, they have pursued perceived respective ethnic interests, largely influenced by historical memory and geopolitics. At the same time, the Young Turks and later the Turkish state engaged in policies, especially toward non-Muslim minorities, that have been described as contradictory, ambivalent, or both in nature, influenced by changing perceptions of citizenship and identity as well as geopolitics. 相似文献
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