The Microbial Rosetta Stone database: A common structure for microbial biosecurity threat agents

Infectious microorganisms are important to multiple communities engaged in biodefense and biosecurity, including the agencies responsible for health, defense, law enforcement, agriculture, and drug and food safety. Many agencies have created lists of high priority infectious microorganisms to prioritize research efforts or to formally control the possession and distribution of specific organisms or toxins. However, the biological classification of infectious microorganisms is often complex and ambiguous, leading to uncertainty and confusion for scientists involved in biosecurity work. To address this problem, we created a database, known as the Microbial Rosetta Stone, which resolves many of these ambiguities and includes links to additional information on the microbes, such as gene sequence data and scientific literature. Here we discuss the efforts to coordinate organism names from pathogen lists from various governmental agencies according to biological relatedness and show the overlap of high-priority organisms from multiple agencies. To our knowledge, this is the first comprehensive coordination of pathogens, synonyms, and correct taxonomic names. The organized tables and visual aids are freely available at http://www.microbialrosettastone.com. This website provides a single location where access to information on a broad range of disease-causing organisms and toxins is available to members of the biosecurity community.     

Identification of authorship using lateral palm print--a new concept

Identification of individual by signature examination could be improved by the lateral palm print examination. By the use of new technique discussed by the author in this paper, the forensic expert can find out very useful information about the writer of writings even without going into the depth of questioned document/signature examination and without the formal or informal handwriting exemplars. The document expert with little more knowledge of the palm print can identify whether the signature is done by hand/leg/anything else, whether the author is right handed or left handed, the approximate age of the author, whether the signature is genuine or forged. Such information of author would be very much useful in elimination of the list of suspects of anonymous letters. In order to fix the authorship, standard and disputed lateral palm prints can be examined either with photographic superimposition technique or with the statistical study of the outline of the lateral palm print or with the standard method as implied in fingerprint examination. The evidential value of such lateral palm print can be placed at par with the finger prints in the court of law and could be placed right on the top of all other scientific evidences.     

Analysis of the CODIS autosomal STR loci in four main Colombian regions

Genotype polymorphism studies at the 13 loci STRs included in the combined DNA index system [CODIS and PCR-based short tandem repeat loci, in: Proceedings of the Second European Symposium on Human Identification, Promega Corporation, Madison, WI, 1998, pp. 73-88; J. Forensic Sci. 46 (2001) 453] (CODIS: D3S1358, HUMvWA31, HUMFGA, D8S1179 D21S11, D18S51, D5S818, D13S317, D7S820, HUMTH01, HUMTPOX, HUMCSF1PO and D16S539) were carried out in a sample of 1429 unrelated Colombian individuals belonging to 25 different departments. As many other countries in Latino-America, Colombia shows an important admixture component, basically integrated by Amerindians, European-descendants and African-descendants. Due to the fact that only partial population analyses have been carried out in the country, the main aim of the present analysis is to establish a database of forensic interest based on the widely used CODIS systems covering the main Colombian regions.     

Contraceptive behavior in adolescence: A decision-making perspective

The contraceptive behavior of adolescent girls was viewed from a decision-making perspective. A semistructured interview protocol was used in interviewing 120 girls aged 12–19 in three clinics (Teen Family Planning, Prenatal, Pediatric Acute Care) at Michael Reese Hospital and Medical Center on (1) demographic in formation; (2) sexual and obstetric history; (3) contraceptive and sexual knowledge, attitudes, and practices; (4) environmental pressures; (5) personality factors; and (6) decision-making style. We found that the girls were generally poor contraceptors. They viewed the costs of contraception (in terms of safety) to be high; and they positively valued physical intimacy, opportunities for which come up unexpectedly and sporadically. These factors, along with their ambivalent views toward pregnancy and childbearing seemed to encourage their risk-taking behavior. Once pregnancy occurred, it was carried to term because of the strong internal and external pressures they felt to have and keep the baby. The peer-led intervention program that we are developing based on the survey findings will focus on (1) the teenagers' lack of accurate and complete knowledge about birth control and conception, (2) their limited sense of options concerning birth control and pregnancy outcomes, and (3) their poor understanding of and lack of insight into what motivates their behavior.This study is part of the investigation being conducted by the YADMAC (Young Adult and Adolescent Decision Making About Contraception) Project at Michael Reese Hospital and Medical Center, 2959 South Cottage Grove, Chicago, Illinois 60616. The authors are all members of the YADMAC research team.Received Ph.D. from the University of Chicago. Current interests are human sexuality and reproductive behavior. Currently at Department of Psychology, St. Xavier College.Received M.D. from the University of Michigan. Current interests are liaison child psychiatry and adolescent sexuality.Received Ph.D. from the University of Chicago. Current interests are early adolescent development issues.Current interests are puberty and sex differences.B. A. candidate in social work, Roosevelt University. Current interests are adolescent sexuality and contraceptive behavior.     

The efficacy of ACH in mitigating serial position effects and confirmation bias in an intelligence analysis scenario

An experimental study was conducted to test whether the version of the structured analytical method Analysis of Competing Hypotheses (ACH) taught by the Cabinet Office to the United Kingdom’s intelligence community provides effective mitigation of the cognitive biases of serial position effects and confirmation bias in an intelligence analysis. ACH had no statistically significant mitigative impact on the proportion of participants that exhibited serial position effects or confirmation bias, or the impact of confirmation bias on the analytical process. The most significant factor that influenced participants’ judgements of the credibility of information was the possibility of deception or dishonesty.     

Can disincentives bring accountability in governance? Experiences of Right to Public Services Guarantee Act in Madhya Pradesh State of India

Many Indian states have enacted Right to Public Services Guarantee Act that promises the delivery of public services to citizens in time‐bound fashion, failing to which, responsible government officials face financial penalty. Therefore, effective service delivery, an indicator of good and responsive governance, is being attempted to be achieved through a “system of disincentive.” The paper tries to analyze if the system of disincentive is effective in ensuring administrative accountability. The paper is based on primary and secondary data. The primary data were collected as part of an action research carried out in 2012, which was supplemented with secondary data collected for different studies during 2015 and 2016. The paper uses a governance accountability framework to analyze implementation of the Act. The study finds that although success rate of implementation of the Act is quite high, the Act presents a narrow idea of accountability. There are no accountability norms for higher officials and elected leaders who head the public service departments. The study also finds that necessary accountability structures have not been developed and there is a dearth of enabling environment that makes accountability structures effective. The study also finds that, despite the provisions for financial penalty, responsible officials find ways to escape. The study exposes weak points in the implementation of the Act, which can be strengthened to achieve desired outcomes. The study can be an important source for course corrections in the states/countries where right to public service delivery is in effect.