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341.
This paper will describe the genesis and philosophy of the Center for Children's Policy. Practice and Research at the University of Pennsylvania (CCPPR), a joint project of the Schools of Law, Medicine and Social Work. The mission of CCPPR was to mobilize the resources of all disciplines engaged in childhood issues across the campus to seek innovative solutions for the crises facing America's children. CCPPR seeks to combine clinical practice, research, and policy in a vertical structure that would maintain linkages at all stages of scholarship, practice, and reform. Five essential structural factors were that the project must be: (a) vertically integrated; (b) interdisciplinary; (c) team-based; (d) child-centered and (e) developmentally informed. This paper can serve as a template for developing similar centers or projects, and will describe our methods, the projects we have undertaken, as well as the pitfalls and challenges of this highly demanding integrative approach.  相似文献   
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We explore the joint venture route to commercializing university owned intellectual property. We present comparisons between two spinouts formed as joint ventures between universities and industrial partners and two spinouts where this was not the case. The research employs a resource-based framework, with new high tech spinout firms (or firms in gestation) facing severe resource and capability constraints. We show that spinouts typically lack the financial means and managerial expertise to acquire the resources and develop the capabilities they need in order to fully exploit the commercial potential of their technologies. We argue that creating a spinout company as a joint venture with an industrial partner, may be a means of overcoming some of the potential problems associated with managing resource weaknesses and inadequate capabilities that may be difficult to achieve as a free-standing spin-out company with or without venture capital backing.  相似文献   
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A comprehensive epidemiological study of the involvement of cannabis and ethanol in motor vehicle fatalities in the Province of Ontario, Canada, is described. The study is based on toxicological analyses of blood and, when available, urine specimens. Ethanol was determined by headspace gas chromatography (GC). For cannabis, the methods employed were radioimmunoassays (RIAs) for screening and gas chromatography/mass spectrometry (GC/MS) for the determination of delta-9-tetrahydrocannabinol (THC) in blood. The study sample consisted of 1169 drivers and 225 pedestrians. THC was detected in the blood of 127 driver victims (10.9%) in concentrations ranging from 0.2 to 37 ng/mL, with a mean of 3.1 +/- 5.0 ng/mL. Ethanol was found in 667 driver victims (57.1%), in concentrations ranging from 9 to 441 mg/100 mL, with a mean of 165.8 +/- 79.5 mg/100 mL. For pedestrians, the incidence of THC and ethanol in the blood was 7.6 and 53.3%, respectively. The incidence of THC in the driver victims in this study constitutes an approximately threefold increase over the results of an Ontario study completed in 1979. At least a part of the increase may be attributed to interstudy differences in analytical methodology for cannabinoids.  相似文献   
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The deterioration of police/citizen relations has had a major impact on the administration of justice. Mutual suspicion, hostility, distrust, and fear have resulted in minimal citizen cooperation and, consequently, an increase in police use of aggressive enforcement procedures. These procedures adversely affect the police as well as the citizenry. Use of aggressive enforcement has two salient consequences: it isolates the police from the citizen, and it generates occupational solidarity among police personnel. Solidarity subsequently increases police/citizen polarization. The process, thus, is circular. The purpose of this study is to empirically investigate the determinants of social isolation and occupational solidarity.To investigate these determinants, a multivariate, multistage conceptual model was developed and analyzed. The findings suggest that the conceptual model, save two minor modifications, fits the data. Policy implications based on these findings are presented and discussed.  相似文献   
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