Genetic variation of 13 STR loci in the four endogamous tribal populations of Eastern India

We have analysed 13 autosomal STR loci in four endogamous tribal populations from two eastern states (Orissa and Nagaland) of India. The Gadaba, Kuvi Khond and Lotha Naga populations have not been analysed for microsatellite genetic variation previously. The allele frequencies for all loci are within the range observed in the geographical region and racial background, though some alleles showed greater variation. Departures from the Hardy-Weinberg equilibrium were tested by three methods and two loci (THO1 and TPOX) showed significant departures for all measures in Gadaba and Lotha Naga populations. The exclusion probability and discrimination probability were high for all analysed loci in all populations. There is no evidence for association of alleles among the STR loci studied. This allele frequency information will be useful for forensic, paternity and population genetic studies.     

Changing the Tobacco Use Management System: Blending Systems Thinking with Actor–Network Theory

Managing “wicked” issues like the tobacco epidemic is addressed using a combination of Open Systems Thinking (OST) and Actor–Network Theory (ANT). OST was used to construct a model of the tobacco problem as a management system acting in a broader environment. This highlighted several problems with the current system but provided no mechanism for reform. ANT, the “sociology of translation,” was used for understanding how change occurs. Unlike systems thinking, ANT focuses the contest for change on heterogeneous networks of human and nonhuman actors that must be constructed through a process of defining and defending models of change, building alliances, gaining public acceptance, and finally achieving institutional acceptance of the reform (or of some compromise). We then show how this dual approach can shed light on a current challenge in controlling tobacco, the issue of product regulation, and the broader issue of harm reduction versus harm elimination.     

Genetic and chemical components analysis of Papaver setigerum naturalized in Korea

Of the 110 species of genus Papaver, only Papaver somniferum and P. setigerum are controlled poppies in Korea. All poppy samples share similar morphology therefore it is important to check if they contain controlled substances such as morphine and codeine for forensic purpose. Since the alkaloid content of Papaver plants varies according to their growing stage, chemical components analysis alone is not enough to identify exact species. In 2010, hundreds of poppy plants suspected to be P. somniferum were found in Jeju Island, South Korea. They had a slightly different but overall similar appearance to P. somniferum. Using GC-MS analysis, codeine, rhoeadine, papaverine, protopine, noscapine, setigeridine and trace amounts of morphine were detected in these samples. Although their chemical components were different from what has been described in literatures for P. setigerum, they could be assumed to be P. setigerum based on their morphological features and GC-MS results. Also, chromosome numbers using their seeds showed 2n=44 and the numbers were in accordance with those of P. setigerum. Nucleotide substitution or insertion/deletion of ITS (internal transcribed spacer), 18S rRNA (ribosomal RNA), rbcL (large subunit of ribulose 1,5-bisphosphate carboxylase), trnL-trnF IGS (intergenic spacer), trnL intron and psbA-trnH were assessed as universal genetic markers for P. setigerum. Also, genetic analysis using six target genes involved in the biosynthesis of benzylisoquinoline alkaloids, including TYDC (tyrosine/dopa decarboxylase), SAT (salutaridinol-7-O-acetyltransferase), BBE (berberine bridge enzyme), COR (codeinone reductase), CYP80B1 ((S)-N-methylcoclaurine 3'-hydroxylase) and NCS (norcoclaurine synthase) were tested as Papaver-specific genetic markers by the existence of their PCR products. From the results, the sequences of the 6 universal genetic markers and 6 Papaver-specific genetic markers for P. setigerum were identified and then Genbank accession numbers of them were registered in NCBI. Also, the trnL intron and psbA-trnH nucleic acid sequences of the 7 Papaver species were identified and registered.     

Does Self-Control Influence Maternal Attachment? A Reciprocal Effects Analysis from Early Childhood Through Middle Adolescence

Objectives

The purpose of this study is twofold. First, this study assesses the extent to which self-control and maternal attachment mutually influence one another. Second, it investigates whether this process continues to occur during adolescence. To date, studies of the etiology of self-control have yet to adequately address these issues, despite the fact that a number of theoretical perspectives emphasize the reciprocal nature of the parent-child relationship.

Methods

The current study seeks to shed light on these issues by examining the relationship between self-control and maternal attachment using structural equation modeling for eight waves of data spanning a period of time that encompasses early childhood through middle adolescence.

Results

The results yield two findings bearing on the adequacy of Gottfredson and Hirschi??s model of self-control development. First, measures of self-control and maternal attachment were found to mutually influence one another during childhood. Second, these effects were reduced to nonsignificance during adolescence.

Conclusions

This study finds that self-control emerges during childhood in a complex manner in which it both shapes and is shaped by parental attachment.     

State Capacity and Terrorism: A Two-Dimensional Approach

Conventional wisdom suggests that dissident groups use terrorism when they face an overwhelmingly more powerful state, yet attacks in developing countries have predominated in the post-Cold War era, suggesting that terrorism is an increasingly weak state phenomenon. Cross-national studies of terrorism find mixed results for how common measures of state capacity influence terrorism. We argue that these indeterminate findings are due in part to a partial understanding of both what constitutes state capacity and how different aspects of state strength or weakness relate to the propensity of groups to use terrorism. We decompose state capacity into two dimensions that we theorize are particularly relevant to dissident groups: military capacity, or the ability to project conventional military force, and bureaucratic/administrative capacity. Our analysis supports the claim that terrorist attacks are more frequently targeted at states with large, technologically sophisticated militaries but less frequently targeted at states with higher bureaucratic and administrative capacity. We also compare two militarily capable states, France and Russia, that have had different recent experiences with terrorism to help illustrate the causal mechanisms involved. Evidence from our models and cases suggest that states can be capable in different ways, and these various capabilities create differing incentives for using terror as a strategic and tactical tool.     

A Criminological Approach to Explain Chronic Drunk Driving

The purpose of this paper is to use criminological theories to explain chronic drunk driving. There is little criminological research explaining recidivist drunk driving with criminological theories. Instead, most researchers posit that repeat drunk driving is explained as a byproduct of substance abuse. Although substance abuse is likely correlated to chronic drunk driving, theoretical explanations need to go further to understand a broader set of social and psychological predictors. Factor analysis and linear regression techniques are used to estimate the relationship between items from two assessment instruments with a number of drunken driving offenses. The sample consists of nearly 3,500 individuals on probation and parole in a Southwestern state. The findings support our contention that criminological frameworks are helpful to understand chronic DUI. We found significant results for volatility, antisocial friends, teenage deviance, and negative views of the law, while controlling for age, gender, marital status, and race. DUIs are a serious problem for the criminal justice system and understanding the individual level correlates of repetitive DUI is crucial for policy development. Further, chronic DUI offers criminologists an opportunity to determine the ability of criminological theories to explain this type of behavior.     

Organizational turnaround: moving beyond one-size-fits-all solutions

Abstract

Literature on organizational turnaround has frequently suggested, but rarely investigated, the possibility that turnaround strategies for failing organizations must be matched to the specific needs of the organization. Building on work related to causes of decline in private sector literature, this study offers a framework for matching strategic interventions to the current state of an organization’s functioning in terms of resources (material and human), coordination (horizontal and vertical), and the environment. Using a panel dataset of New York City schools, we find that two understandings of turnaround that often appear mutually exclusive—that an organization can improve performance by shoring up weaknesses and that an organization should play to its current strengths—can complement each other and may both appropriately describe different types of organizational challenges.