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151.
Use of an Automated Nested Multiplex Respiratory Pathogen PCR Panel Postmortem in the Pediatric Forensic Setting 下载免费PDF全文
Tiffany Baker M.D. Ph.D. Cynthia Schandl M.D. Ph.D. Susan Erin Presnell M.D. James Madory D.O. Frederick S. Nolte Ph.D. Nicholas Batalis M.D. 《Journal of forensic sciences》2017,62(5):1223-1228
Respiratory pathogens have been detected in forensic investigations using multiple techniques; however, no study has examined the use of automated, nested, multiplex polymerase chain reaction (ANM‐PCR), commonly used in living patients, in the forensic setting. This retrospective study assessed the utility of ANM‐PCR in detecting respiratory pathogens in the pediatric forensic setting. Respiratory samples from 35 cases were tested for up to 20 respiratory pathogens. 51.4% of these cases yielded a positive ANM‐PCR result, 20% of which were considered the cause of or contributory to death. The most commonly detected pathogens were rhinovirus/enterovirus and respiratory syncytial virus, and these were the only pathogens determined to play a significant role in cause of death. The sampled sites and postmortem intervals tested did not affect the likelihood of a positive or negative test. ANM‐PCR panels are effective, affordable, and rapid ancillary tools in evaluating cause of death in the forensic pediatric population. 相似文献
152.
Nicholas Blagden Christian Perrin Sam Smith Faye Gleeson Laura Gillies 《Journal of Sexual Aggression》2017,23(2):151-166
Understanding how sexual offenders experience prison and its environment is important because such experiences can impact on rehabilitation outcomes. The purpose of this research investigation was to explore the rehabilitative and therapeutic climate of a recently re-rolled sexual offender prison. The research took a mixed methods approach and consisted of quantitative and qualitative phases. There were differences between prisoners and staff on their perception of the prison climate and for prisoner and staff relationships. The qualitative results helped to explain the quantitative findings and added a more nuanced understanding of the experience of the prison, the nature of prisoner and staff relationships and the opportunities for personal growth within the prison. The study has important implications for prisons that co-locate sexual offenders and want to provide an environment conducive to rehabilitation. 相似文献
153.
In this article, we consider the phenomenon of message crimes involving harm to wildlife from a sociological and criminological perspective. Using a case study of dissident Nordic hunters killing protected wolves to send a message to the state agencies responsible for their conservation, we engage philosophically with the question of wildlife victimhood and why interspecies violence is unjustifiable as a mode of political dissent. As an alternative to the species justice perspective in green criminology, we examine how the acts disrespect animals as moral subjects of public communication and frustrate dialogue regarding what is owed to them in terms of political justice. 相似文献
154.
Nikeea Copeland-Linder Sharon F. Lambert Yi-Fu Chen Nicholas S. Ialongo 《Journal of youth and adolescence》2011,40(2):158-173
This study examined the longitudinal association between contextual stress and health risk behaviors and the role of protective
factors in a community epidemiologically-defined sample of urban African American adolescents (N = 500; 46.4% female). Structural
equation modeling was used to create a latent variable measuring contextual stress (community violence, neighborhood disorder,
and experiences with racial discrimination). Contextual stress in 8th grade was associated with aggressive behavior and substance
use 2 years later for boys. For girls, contextual stress predicted later substance use, but not aggressive behavior. High
academic competence and self-worth reduced the impact of contextual stress on substance use for boys. Implications for intervention
and directions for future research on health risk behaviors among African American adolescents are discussed. 相似文献
155.
The sixth MDG aims 'to combat HIV/AIDS, TB, malaria and other diseases'. The residual category of 'other diseases' has become the focus of intense interest, partly because it has provided an opportunity to increase resources for the control of the mostly parasitic 'neglected tropical diseases' (NTDs). Intense lobbying has secured large amounts of funding from donors, as well as generous donations of medicines from the major drug companies. A massive programme is now underway to treat the parasites of the poor in Africa via integrated vertical interventions of mass drug administration in endemic areas. The approach has been hailed as remarkably effective, with claims that there is now a real prospect of complete control and, for some NTDs, even elimination. However, a closer look at evaluation and research data reveals that much less is known about what is being achieved than is suggested. Competition between implementing organisations is leading to potentially counterproductive exaggerations about treatment coverage. Detailed local-level research in Uganda and Tanzania shows that actual rates of drug take-up among target populations are often lower than is necessary to effectively control the diseases, and that methods of drug distribution may even lead to active resistance to treatment. If current trends are not corrected, declining rates of NTD infection will not be sustained. Much more rigorous and effective monitoring is essential. 相似文献
156.
157.
Allgeier L Hemenway J Shirley N LaNier T Coyle HM 《Journal of forensic sciences》2011,56(5):1245-1249
The validity and feasibility of using DNA collection cards in the field for preservation and analysis of Cannabis sativa genotypes were investigated using a highly specific hexanucleotide marker. Collection cards were submitted to the National Marijuana Initiative, which selectively trained and managed the collection of specific types of samples from a variety of participating agencies. Samples collected at seizure sites included fresh marijuana leaf samples, dried "dispensary" samples, U.S. border seizures, and hashish. Using a standardized PCR kit with custom-labeled oligonucleotide primers specific to marijuana, collection cards produced eight genotypes and 13 different alleles, extremely low baselines, and no cross-reactivity with control plant species. Results were produced from all sample types with the exception of hashish. Plant DNA collection cards represent an easily implementable method for the genetic identification and relatedness of C. sativa street and grow site-seized samples with applications for databasing and market disruption. 相似文献
158.
159.
Kelsey Michael Bradshaw Brad Donohue Chad Cross Jessica Urgelles Daniel N. Allen 《Journal of family violence》2011,26(7):545-549
Parental dissatisfaction with children appears to be associated with child maltreatment. However, little is known regarding the specific domains of parental dissatisfaction that may increase child maltreatment potential, particularly in perpetrators of child maltreatment where substance abuse is present. In this study, responses to the Child Abuse Potential Inventory (CAPI) and a scale measuring parental satisfaction in 11 domains were examined in a sample of 82 mothers who were referred for treatment of substance abuse and child neglect by the local child protective service agency. Results indicated that mothers were relatively most satisfied with their children overall, and least satisfied in domains that were relevant to discipline (i.e., following house rules, compliance, reaction to redirection and punishment, completion of chores). Five of the 11 areas of parental satisfaction that were assessed evidenced negative correlations with child abuse potential, indicating that as satisfaction increased, abuse potential decreased. However, when correlation analyses excluded participants with elevated CAPI Lie scale scores (a measure of social desirability), only overall happiness demonstrated a significant negative correlation with child abuse potential. These results suggest that while associations are present among measures of parental satisfaction and child abuse potential, these associations are moderated to some extent by social desirability, which may help explain some of the inconsistencies reported in prior studies of parental satisfaction and child maltreatment potential. 相似文献
160.