Estimating Individual Contributions to Complex DNA SNP Mixtures.,

High‐throughput sequencing (HTS) of large panels of single nucleotide polymorphisms (SNPs) provides an alternative or complimentary approach to short tandem repeats (STRs) panels for the analysis of complex DNA mixture forensic samples. For STRs, methods to estimate individual contribution concentrations compare capillary electrophoresis peak heights, peak areas, or HTS allele read counts within a mixture. This article introduces three approaches (mean, median, and slope methods) for estimating individual DNA contributions to forensic mixtures for HTS/massively parallel sequencing (MPS) SNP panels. For SNPs, the major:minor allele ratios or counts, unique to each contributor, were compared to estimate contributor proportion within the mixture using the mean, median, and slope intercept for these alleles. The estimates for these three methods were typically within 5% of planned experimental contributions for defined mixtures.     

Better law‐making and the interinstitutional (dis)agreements: Some comments

This work argues that there is no univocal interpretation of what regulatory policy is and pursues. Taking the strategy of the European Commission as a starting point only, it addresses more specifically the Union legislature's perspective, which, in a democratic decision‐making process, cannot compromise its autonomy. In the unique constitutional universe of the European Union, the “Better Law‐Making” agenda pursues an important additional objective: facilitating the very process of adopting legislation by means of interinstitutional conflict prevention mechanisms and through a common approach to interpretation and implementation of primary law. That is the main purpose of the Interinstitutional Agreements on the quality of legislation, which place them in the position of a sort of soft constitutional law.     

Memories,Drama and Dreamers: Proposals to Address the Representation of the Latin World in the Face of the Telenovela Crisis

The broadcast of the Latin American telenovela in the United States has been approached from many perspectives. One approach is the study of how the Latin reality is perceived through stories, themes and iconographic elements. This article analyses the different forms of representation of reality as promotors of the identification, production of mental images and memory to maintain the interest of the spectators. A series of initiatives have been proposed so that the stories are more in line with the tastes and expectations of a complex, multicultural and multigenerational audience.     

‘Friend or Foe?’: Brexit and French Bashing in the Conservative Parliamentary Party (2016–2022)

This article explores the extent of anti-French rhetoric in Conservative parliamentary discourse since 2016. It argues that up to the end of Liz Truss's extremely brief period of power, a fair number of Conservative MPs embarked on an escalation of tabloid-like anti-French bashing after the election of Boris Johnson, in an attempt to mimic the dramaturgy staged by their leader, while those who tried to provide a more positive discourse were left crying in the wilderness. Moreover, positive attempts to renew the relationship essentially came from MPs who had specific interests to defend, either in terms of representation of French residents in their constituencies or out of loyalty to family connections. Post-Johnson, a more realistic and sensible discourse is anticipated, but damaging traces of this populist drift are likely to continue.     

Has machine learning rendered simple rules obsolete?

European Journal of Law and Economics - Epstein (Simple rules for a complex world, Harvard University Press, Cambridge, 1995) defended the superiority of simple legal rules over complex,...