microRNA Detection in Blood,Urine, Semen,and Saliva Stains After Compromising Treatments

Evaluation of microRNA (miRNA) expression as a potential method for forensic body fluid identification has been the subject of investigation over the past several years. Because of their size and encapsulation within proteins and lipids, miRNAs are inherently less susceptible to degradation than other RNAs. In this work, blood, urine, semen, and saliva were exposed to environmental and chemical conditions mimicking sample compromise at the crime scene. For many treated samples, including 100% of blood samples, miRNAs remained detectable, comparable to the untreated control. Sample degradation varied by body fluid and treatment, with blood remarkably resistant, while semen and saliva are more susceptible to environmental insult. Body fluid identification using relative miRNA expression of blood and semen of the exposed samples was 100% and 94%, respectively. Given the overall robust results herein, the case is strengthened for the use of miRNAs as a molecular method for body fluid identification.     

Idealism versus realism in institutional choice: Explaining electoral reform in Poland

One of the most significant, yet not fully explained, institutional decisions in post‐Communist Europe was Poland's adoption of a moderate proportional representation system for the 1993 general election. This article argues that the new electoral system was not entirely based on any normative notion of democratic governance, and that the adoption did not immediately follow from the assumptions of rational choice theory. The 1993 electoral system was largely attributable to patterns of interaction between political parties that had become known, been practised and accepted since the fall of Communism. In reality, the eventual system was built up incrementally in several stages, but the Polish way of ‘muddling through’, albeit contentious and protracted, seems to have worked well for the Polish people.     

Book review

Post‐Modernism and the Social Sciences: Insights, Inroads, and Intrusions, by Pauline Marie Rosenau. Princeton University Press: Princeton. 1992. pp.229.