Hair and urine analysis: relative distribution of drugs and their metabolites

This work studies the distribution of cocaine and heroin metabolites in hair and urine of living polidrug abusers. Cocaine, benzoylecgonine (BEG), ecgonine methyl ester (EME), morphine, codeine and 6-monoacetylmorphine (6-MAM) were simultaneously extracted and analyzed by GC/MS in SIM mode. The results obtained show a different distribution of heroin and cocaine metabolites in urine and hair. In urine, we generally find BEG and EME for cocaine abuse, and morphine for heroin abuse. In hair, we detect cocaine and MAM as major metabolites for cocaine and heroin abuse, respectively.     

Consensus,compromise, justice and legitimacy

Could the notion of compromise help us overcoming – or at least negotiating – the frequent tension, in normative political theory, between the realistic desideratum of peaceful coexistence and the idealistic desideratum of justice? That is to say, an analysis of compromise may help us move beyond the contrast between two widespread contrasting attitudes in contemporary political philosophy: ‘fiat iustitia, pereat mundus’, on the one side, and ‘salus populi suprema lex’, on the other side. More specifically, compromise may provide the backbone of a conception of legitimacy that mediates between idealistic (or moralistic) and realistic (or pragmatic) desiderata of political theory, i.e. between the aspiration to peace and the aspiration to justice. In other words, this paper considers whether an account of compromise could feature in a viable realistic conception of political legitimacy, in much the same way in which consensus features in more idealistic conceptions of legitimacy (a move that may be attributed to some realist theorists, especially Bernard Williams). My conclusions, however, are largely sceptical: I argue that grounding legitimacy in any kind of normatively salient agreement does require the trappings of idealistic political philosophy, for better or – in my view – worse.     

A New Predictor of Local Financial Distress

The development of predictive models for financial distress is a recurring topic in both private and public contexts, although currently its repercussions are greater in the public sphere, where efforts are being made to define new warning systems for fiscal crises. The present study thus aims first to show the similarities and differences between the absolute and relative models based on a 10-point scale, in order to subsequently combine the positive aspects of both proposals to find a system that can determine local fiscal distress in a more robust way.

The results obtained show that the optimum predictive system is a slight variant of the model proposed by Kloha et al. (2005) Kloha, P., Weissert, C. S. and Kleine, R. 2005. Developing and testing a composite model to predict local fiscal distress. Public Administration Review, 65(3): 313–323. [Crossref], [Web of Science ®] , [Google Scholar]. This variant consists of the inclusion of two indicators of financial independence proposed by Zafra-Gómez et al. (2009a) Zafra-Gomez, J. S., López-Hernández, A. M. and Hernández-Bastida, A. 2009a. Developing an alert system for local governments in financial crisis. Public Money &; Management, 29(3): 175–82. [Taylor &; Francis Online], [Web of Science ®] , [Google Scholar] for which an alert threshold has been empirically determined.     

Mandatory or Not Mandatory Reporting? Insights From Italian Bank Foundations

In the Italian nonprofit field, bank foundations face an increasing demand to account for their grant activity in forms that go beyond traditional financial statements. Consequently, bank foundations have developed specific reports in accordance with a 2001 Italian law that requires a mission report to be included within financial statements. This study investigates the peculiarities of social reporting documents in terms of standards used and formal characteristics, revealing different adoption levels. Contributing to an ongoing debate, the analysis of the reporting practices underlines how the due by law on social accounting could hamper the disclosure in nonprofit organizations.     

Are healthier people happier? Evidence from Chile and Uruguay

Based on data from the Latinobarómetro, this study analyses data on happiness to establish the probability that an individual is happy. The focus is put on self-reported health status as a key aspect in increasing levels of happiness. The probability of being happy is econometrically estimated by probit models for each country. Results show that the main relationship is between happiness and health status. Whether this is a causal effect or only a correlation, is not clear. This issue is explored by using propensity score matching methods. These show that good health status increases the probability of being satisfied with life by between 13 and 17 percentage points. In line with the literature, we find that the relationship between age and happiness is U-shaped, with happiness at its lowest point at the age of 48.2.

Les personnes en bonne santé sont-elles plus heureuses ? Données concrètes en provenance du Chili et de l'Uruguay

Sur la base de données tirées du Latinobarómetro, cette étude analyse des données sur le bonheur afin d'établir la probabilité du bonheur de personnes données. L'accent est mis sur l'état de santé présenté par la personne elle-même comme aspect clé du niveau croissant de bonheur. La probabilité de bonheur est estimée économétriquement au moyen de modèles probit pour chaque pays. Les résultats indiquent que le principal rapport est celui qui relie le bonheur et l'état de santé. Quant à savoir si c'est là une relation de cause à effet ou seulement une corrélation, ce n'est pas évident. Cette question est traitée au moyen de méthodes d'appariement par score de propension, qui montrent qu'un bon état de santé accroît la probabilité de se sentir satisfait de sa vie de 13 à 17 pour cent. Conformément aux documents écrits sur ce thème, nous constatons que le rapport entre l'âge et le bonheur est en forme de U, le bonheur atteignant son niveau le plus bas à l'âge de 48,2 ans.

¿Son más felices las personas sanas? Hallazgos en Chile y Uruguay

A través del Latinobarómetro para Chile y Uruguay 2007, se estima a través de modelos probit la probabilidad de que un individuo sea feliz. La principal correlación positiva se da entre la felicidad y el buen estado de salud. A efectos de controlar la potencial heterogeneidad observable de esta variable, se utilizan técnicas de correspondencia encontrando que tener buena salud aumenta entre 13 y 17 puntos porcentuales la probabilidad de ser feliz para los datos agrupados regionales. Consecuentemente con la literatura, se encuentra una forma convexa con respecto a la edad, siendo los 48.2 años la edad de mínima felicidad.

As pessoas mais saudáveis são mais felizes? Evidências do Chile e Uruguai

Baseado em dados do Latinobarómetro, este estudo analisa dados sobre felicidade para estabelecer a probabilidade de um indivíduo ser feliz. O enfoque é dado na condição de saúde auto-relatada como aspecto-chave para aumentar os níveis de felicidade. A probabilidade de ser feliz é econometricamente estimada por modelos probit para cada país. Resultados mostram que a principal relação é entre felicidade e condição de saúde. Se isto é um efeito causal ou apenas uma correlação, não está claro. Esta questão é explorada utilizando-se métodos PSM (Propensity Score Matching). Estes métodos mostram que boas condições de saúde aumentam a probabilidade de satisfação com a vida em cerca de 13 a 17 pontos percentuais. Em sintonia com a literatura, constatamos que a relação entre idade e alegria tem a forma de U, com a alegria em seu ponto mais baixo na idade de 48.2.     

Suicidal poisoning with barium chloride

A 49-year-old male pharmacist suffering from depression phoned the emergency services telling of how he had ingested barium chloride. He was found semicomatose in bed and resuscitation attempts were to no avail and he died at the scene. A white plastic container labelled "Barium chloride... Poison", and a book with a writing on a blank page... "give sulphate... SO(4)" were found.At autopsy, 1l of whitish-yellow fluid was found in the stomach.Autopsy barium levels were: blood 9.9mg/l; bile 8.8mg/l; urine 6.3mg/l; gastric 10.0g/l.Cause of death was given as cardiorespiratory arrest due to barium chloride poisoning.The issue of barium toxicity in a variety of itatrogenic and non itatrogenic situation is discussed together with the two only other cases of suicidal barium ingestion, and the feasibility of early intervention at the scene by an emergency team.     

Financial Sustainability as a Driver for Transparency and E-Democracy: A Comparative Study in Italian and Spanish Local Governments

Today expectations of accountability and trustworthiness in governing entities is greater than ever before. The process of change has been given impetus by new information and communication technologies resulting in e-government and e-democracy. This research aims to analyze transparency and democratic participation in Italian and Spanish LGs. The web pages of Italian and Spanish LGs with more than 100,000 inhabitants are analyzed using twenty determinants of fiscal transparency and eight determinants of e-democracy. Results show considerable similarity between Italian and Spanish LGs with regards to the disclosure of financial information, while the adoption of e-democracy tools requires further development in both countries.     

Performance Measurement in Italian and Spanish Local Governments: Comparative Policy Analysis

NPM reforms have become a global trend and performance management systems are considered suitable to enhance the decision-making process and accountability. The aim of the paper is to carry out a comparative study on the adoption of performance measurement tools in Italian and Spanish (medium-sized and large) local governments. It seeks to find out how widespread these tools are and how their usefulness is perceived. The results show differences between the two countries and that the presence of professional managers – experienced with performance measurement tools – positively affects the adoption of these tools. Moreover, performance measurement tools are perceived as a support for accountability purposes.     

Tubali's trip: Rethinking informality in the study of West African labour migrations

This article focuses on the work and travels of Tubali, a Hausa-speaking migrant from the region of Tahoua in the Republic of Niger. In a journey that lasted four years and took him across Niger, Nigeria, Cameroun, Equatorial Guinea, Gabon and the Republic of the Congo, Tubali operated in contexts usually characterised as “informal”: he travelled without documents or work permits, and was supported by institutions that elude state control and yet grant access to financial resources, travel support and employment opportunities to travellers unable or unwilling to follow official avenues. These migrants rely on the operation of relationships that, in Tubali's case, are mostly impromptu, formed on the basis of shared ethnicity, religion and region of origin. This article interprets Tubali's trip in relation to the meanings attributed to this way of working and travelling in Tahoua's society. It investigates the conceptual and political consequences of characterising these migrants' practices as “informal” and discusses analytical alternatives.