Genetic markers in human bone: I. Deoxyribonucleic acid (DNA) analysis.

Deoxyribonucleic acid (DNA) was isolated from a number of spongy and compact human bone tissue specimens, and the yield was estimated on a "per milligram of starting tissue" basis. DNA was, in addition, isolated from a number of corresponding blood and bone tissue specimens. Spectrophotofluorometry and ethidium bromide visualization on minigels were used to estimate the quantity and degree of degradation of DNA. The DNA from several blood-bone pairs is shown to give concordant restriction fragment length polymorphism (RFLP) typing results by two different typing protocols with five different single-locus probes. DNA from several additional blood-bone pairs is shown to give concordant results for human leucocyte antigen (HLA)-DQ alpha phenotypes following polymerase chain reaction (PCR) amplification and hybridization to specific allele-specific oligonucleotide (ASO) probes, and for the variable numbers of tandem repeats (VNTR) length polymorphisms 3' to the human apolipoprotein B (APOB) gene following PCR amplification with specific primers and analysis of the products by electrophoresis and ethidium bromide visualization.     

Le contrôle politique des organismes autonomes à fonctions régulatrices et quasi-judiciaires

Sommaire. Le contrǒle politique des organismes autonomes à functions régulatrices et quasi-judiciaires est celui qu'exercent le Parlement et le gouvernement sur l'opportunité des mesures qu'adoptent ces organismes et qui doivent ětre appréciées en regard de l'intérět général. L'octroi d'un large pouvoir discrétionnaire en matière d'élaboration et d'application de la politique suivant un processus qualifié par notre droit de quasi-judiciaire soulève des difficultés considerables qui nous obligent à revoir les principes měmes qui régissent les rapports entre ces « tribunaux administratifs » et l'autorité politique parlementaire et gouvernementale. Les techniques de contrǒle utilisées dans la législation relative aux grandes régies fédérales notamment, la cct , le crtc , l’one , sou-lèvent également des difficultés. Ainsi, lorsqu'existe un droit d'appel au gouverneur en conseil ou au ministre, on s'interroge sur la portée de ces recours par rapport aux recours à la Cour fédérale prévus par la Loi sur la Cour fédéraLe ou d'autres lois particulières. De měme lorsque la législation prévoit des moyens de contrǒle à priori, tel le pouvoir d'émettre des directives, on se demande quelles sont les sanctions possibles dans le cas où le tribunal refuse ou néglige d'y donner suite. Ces problèmes sont au coeur des recherches en cours sur certains aspects du développement des principaux tribunaux administratifs ou organismes autonomes à functions régulatrices et quasi-judiciaires. Abstract. Political control of autonomous regulatory and quasi-judicial bodies is the control exercised by Parliament and the government over the actions of these bodies to assess their opportunity in regard to the general interest. The granting of wide discretionary power in the elaboration and application of policies following a procedure qualified in law as quasi-judicial raises considerable difficulties with respect to the very principles which determine the relations between these administrative tribunals and parliamentary and governmental political authority. With respect to the control techniques employed in the legislation relating especially to the major federal commissions such as the ctc , the crtc and the neb , these difficulties are particularly evident. On the one hand, when a right of appeal to the Governor-in-Council or the Minister exists, what is the extent of these remedies in relation to the recourse to the Federal Court granted by the Federal Court Act or other special statutes? When legislation provides for a priori controls such as the power to issue directives, what are the possible sanctions in the event that the tribunal refuses or neglects to follow them? These problems are at the very heart of present research on certain aspects of the development of the major administrative tribunals and autonomous bodies exercising regulatory and quasi-judicial functions.     

A Public Choice Analysis of Endangered Species Listings

Sizable economic consequences may resultfrom listing under the Endangered SpeciesAct (ESA). Potentially adversely affectedparties will attempt to use the politicalprocess to protect their interests. Thequestion is, “are listing determinationssubject to political manipulation?” Inthis paper, we explore empirically thepossibility that implementation of the ESAis determined, in part, by politicalconsiderations. Specifically, weinvestigate whether states with strongcongressional representation are able touse their political muscle to reduce thenumber of listings in their states, ascompared to states with weak congressionalrepresentation. Controlling for otherfactors, we find that states with greaterrepresentation on the U.S. Fish andWildlife Service’s budgetary oversightsubcommittee in the U.S. House ofRepresentatives have significantly fewerESA listings than states with weakerrepresentation on that subcommittee.     

Indigenous rights in El Salvador: Prospects for change

Conclusion In 1996, the National Association of Salvadoran Indians participated in a UN-sponsored conference on the development of forest resources. Their involvement in the conference highlighted the growing international presence of Salvadoran indigenous organizations. Unfortunately, there is also very limited information available on these groups. As some have commented: The Salvadoran Indians … are an invisible or ghostly presence in the country: cautious in their public presence as an ethnic community, officially non-existent—yet still recognised by neighbours, local municipal governments and, most importantly, by themselves as indios. As the country becomes more accessible to researchers and as indigenous Salvadorans gain a stronger foothold in the international forum, it is very likely indigneous peoples will emerge from the historical shadows to forcefully claim their rights as distinct members of Salvadoran society. The obstacles they face are not inconsequential. State opposition to indigenous organizations is strong and popular perceptions are often harder to dislodge than state policies. The widespread support gained by organizations like ANIS during the civil war proves that there is sympathy for indigenous rights. It remains to be seen to what extent ANIS and other organizations can use this support, and that of indigenous allies around the world, to promote the goals and aspirations of indigenous Salvadorans. While the issue of indigenous rights has long been discussed in other countries, it is only beginning to be addressed in El Salvador.     

The Institutional Basis of Secessionist Politics: Federalism and Secession in the United States

According to the literature on secession, the most importantdeterminant of secessionist sentiment is a high level of grievanceexperienced by the would-be secessionist group. However, therationale behind using secession (as opposed to another strategy)as a grievance-amelioration strategy remains almost completelyunexplained. This article contends that the institutional settingin which political conflict and grievance are experienced playsa crucial role in whether secession is conceived of as a viableoption. This contention is tested by examining the institutionalenvironment of federalism and the role it played in secessionin the United States in 1860 and 1861. The United States wasuniquely vulnerable to secessionist pressures—as are allfederal states, potentially—because of institutional structuresthat gave constituent states a high level of institutional authorityand capacity; this, in turn, contributed to a discourse of states'rights that included the contested right to secede.     

When winners are losers: The stalemate of Australian politics

The 1998 federal election emphasizes the fact that in Australian politics the power of the major parties remains strong both in terms of voter identification and in terms of setting the policy agenda on which political contests are fought, say Professors John Wanna and Patrick Weller from the Department of Public Policy at Griffith University, Brisbane, Australia. The results of the election nevertheless illustrate a substantial level of discontent in the community, and the term of the next government promises frequent stalemates, as the clash between the House of Representatives and the Senate makes the passing of controversial legislation difficult.