Optimisation of choline testing using Florence Iodine reagent,including comparative sensitivity and specificity with PSA and AP tests

The detection of semen in forensic science is essential in cases of sexual assault but can be problematic in the absence of spermatozoa. Choline is known to occur in high concentrations in seminal fluid and the Florence Iodine test for its detection has been used in forensic science for many years, however very little is documented regarding its sensitivity and specificity in forensic casework. This paper describes the optimisation of the choline Florence Iodine test (FI) and investigates the sensitivity and specificity of the test against different body fluids, food and drink substances, cleaning products and laboratory chemicals. Comparative testing against Acid Phosphatase (AP) and Prostate Specific Antigen (PSA Seratec®) tests is described and shows that the FI test has greater specificity than the PSA test which cross reacts with a number of body fluids.     

Introduction to issue number two

“Groen Links (Green Left) is Holland's new, radical, green party, which occupies a space to the left of the Social Democrats. It has been formed through the unification of four smaller left wing parties, and as its name makes clear it involves a conscious attempt at a fusion of red and green politics.”     

Viewpoint: Look Before Taking Another Leap for Mankind—Ethical and Social Considerations in Rebuilding Society in Space

Commercial space travel is looking more like a real possibility than science fiction, but tied to that ambition we may be held back by the gravity of emerging ethical dilemmas. This viewpoint article surveys a range of social, economic, and political questions, and critically evaluates reasons why we should explore space. The usual ethical issues related to environmental and safety concerns are just the beginning, as there are other interesting questions, such as: what would be a fair process for commercializing or claiming property in space; how likely would a separatist movement be among space settlements who want to be free and independent states; and are reasons to explore space, like for adventure, wanderlust, or “backing up the biosphere,” good enough to justify our exploration of space? The point here that we should explore space; and if we are to move forward with our journey, which may be unstoppable anyway, then we should seriously consider these issues. At the least, this would give the public more confidence—amid questions of misplaced priorities and wasteful spending, along with an increased focus on ethics in science—that we are looking ahead before we take another leap for mankind.     

Funding Global Public Goods: The Dark Side of Multilateralism

The funding of global public goods, such as climate mitigation, presents a complex strategic problem. Potential recipients demand side payments for implementing projects that furnish global public goods, and donors can cooperate to provide the funding. We offer a game‐theoretic analysis of this problem. In our model, a recipient demands project funding. Donors can form a multilateral program to jointly fund the project. If no program is formed, bilateral funding remains a possibility. We find that donors rely on multilateralism if their preferences are relatively symmetric and domestic political constraints on funding are lax. In this case, the recipient secures large rents from project implementation. Thus, even donors with strong interests in global public good provision have incentives to oppose institutional arrangements that promote multilateral funding. These incentives have played an important role in multilateral negotiations on climate finance, especially in Cancun (2010) and Durban (2011).     

Technical efficiency measurement within the manufacturing sector in Côte d'Ivoire: A stochastic frontier approach

This article analyses the productive performance in four manufacturing sectors of the Ivorian economy: textiles and garments, metal products, food processing, wood and furniture. To appraise the productive performance, econometric production frontier models are estimated, illustrating the maximum output attainable from a given quantity of inputs. The frontier and firm efficiency scores are derived from stochastic production functions estimated on cross-sectional data. The stochastic specification of the models allows for the decomposition of the error term into two components, one the normal random effect and the other to account for technical inefficiency that we explain by various exogenous variables describing the economic and institutional environment. Firm size proves to be a statistically significant determinant of the productive performance. Across the four sectors, the positive impact of being large compensates the negative effect of a formal institutional status in an environment where government regulations still prevail.