Two fatal intoxication cases with imidacloprid: LC/MS analysis

Imidacloprid [1-(6-chloro-3pyridylmethyl)-N-nitroimidazolidin-2-ylideneamine] is a new and potent nitromethylene insecticide with high insecticidal activity at very low application rates. It is the first highly effective insecticide that, like nicotine, acts on the nervous system, causing blockage of postsynaptic nicotinergic acetylcholine receptors. Two fatal cases with this insecticide in two male individuals, of 33 and 66 years old, are presented. An LC/MS with electrospray method for measuring imidacloprid and its metabolites in post-mortem samples is described. In the chromatographic separation, a reverse-phase column XTerra MS C18 (2.1mm i.d.x 150 mm, 5 microm) was used and the mobile phase composed with acetonitrile and 0.1% formic acid (15:85), at a 0.25 mL/min flow rate. Samples were prepared with a liquid-liquid extraction procedure with dichloromethane. Calibration curves for imidacloprid in blood and urine samples were linear from 0.2 to 15 microg/mL. The mean recovery was 86% with a coefficient of variation of +/-5.9%. The detection limit was 0.002 microg/mL. Quantitative results were obtained for all post-mortem matrices available of the two fatal cases: blood, urine, stomach contents, lung, liver and kidney. The imidacloprid blood concentrations found in two-cases were 12.5 and 2.05 microg/mL. The authors validated a method to detect and quantify imidacloprid in post-mortem samples, and to our knowledge for the first time a post-mortem tissue distribution was performed on various samples for this insecticide.     

Gender Bias in Attributions of Responsibility for Abuse

The bulk of previous research investigating attributions of responsibility in victimization scenarios have portrayed the assailant as male and the victim as female. The present study varied gender of the participant, gender of the assailant, and gender of the victim in order to examine gender bias in attributions of responsibility in abuse scenarios. Male and female participants were presented with scenarios depicting an abusive interaction between two males, two females, or a male and a female character and then made judgements of responsibility either with or without the narratives present. The results indicated that attributions made by females were biased against male victims of a male assailant when judging actions of the assailant. Attributions made by females and, to a lesser degree, attributions made by males were biased against the victim when the assailant and the participant were of the same gender and attributions of assailants' actions were made without the narrative present. In the analysis of attributions of actions of the victim, males attributed more responsibility to male than female victims. It is concluded that gender of all parties may be an important consideration when judging responsibility in victimization scenarios.     

The reliability of immunoassay for determining the presence of opiates in the forensic setting

Urine immunoassays are commonly used as a rapid screen for drugs of abuse in emergency room, hospital, clinic, and forensic settings. The authors were concerned whether or not a negative screen of the urine for opiates was of significance and indicative that analysis of blood for opiates was not necessary. Specifically, we wished to determine whether a negative test for opiates by immunoassay absolutely rules out an acute overdose, and if not, what percentage of cases with negative results have opiates in the blood. A retrospective analysis was performed using the toxicology results for cases ruled an acute narcotic overdose at the Bexar County Medical Examiner's Office between 1998 and 2003. One hundred eighty-three cases met the criteria for the study. A false-negative rate of approximately 15% was found using an immunoassay as compared with blood analysis for narcotics. The authors feel that while this rate may be acceptable in a clinical setting, it is unacceptable in a forensic setting.     

The decision process of a professionalized legislature: A cognitive anthropology approach

Political science research indicates that some state legislatures have become more professionalized, i.e., taken on many of the characteristics of Congress such as yearround sessions, professional staffs, and formalized bill processes. But is professionalization a factor in legislators' decision making? Triangulated analysis—consensus, cluster, and multidimensional scaling—of two paired comparisons that were administered to a stratified random sample of a professionalized legislature suggests that some of the professionalized characteristics do affect legislators' perception of their decision making on one area of policy, the regulation of and resource allocation to public universities. The analysis also shows that influences on legislators' decision process fluctuate according to issue.     

DNA typing of short tandem repeat loci on Y-chromosome of Greek population

Haplotype, allele frequencies and population data of nine Y-chromosome STR loci, DYS385I, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, were determined from a sample of 69 unrelated Greek male individuals.     

Depression Among Mexican Women: The Impact of Nonviolent Coercive Control,Intimate Partner Violence and Employment Status

There is significant empirical evidence documenting the link between intimate partner violence (IPV) and incidence of depression symptoms. This study explores the impact of intimate partner violence, nonviolent spousal coercive control, and women’s employment status on the incidence of depression symptoms in a sample of Mexican women. Results from regression models suggest different types of abusive relationships have differential impacts on incidence of depression. Specifically, a woman’s employment status contributed to the risk of depression in the context of prevalent nonviolent spousal controlling behaviors. On the other hand, employment status did not contribute to the risk of developing depression symptoms when women were in relationships where physical violence was not coupled with controlling behaviors. Results of the study are discussed in the context of the Mexican culture, as well as implications for the treatment of IPV among Mexican women.     

Trends in involuntary psychiatric hospitalization in Israel 1991-2000

BACKGROUND: Though information about involuntary psychiatric hospitalizations (IPH) is crucial for the planning of Israel's National Mental Health Care Policy, very few studies have been carried out to date on this subject. AIMS: To identify trends in first IPH to all inpatient psychiatric settings in Israel. METHOD: The sample included all admissions of adults (18 years and older) over the ten-year period, 1991-2000, according to the registration of such admissions in the National Psychiatric Case Registry. RESULTS: A 2.4-fold increase was found in first IPH over the decade studied. The typical profile of the involuntarily admitted patient was that of a native-born Jewish male, aged 18-24 or 65 and older, single, with less than 8 years of education, and with a diagnosis of schizophrenia or delusional psychosis. CONCLUSIONS: These findings suggest the need for improving the interfaces between hospital and community services, and for preparing specific guidelines to extend the use of involuntary ambulatory treatment orders. Further study is needed to explore the respective roles of involuntary inpatient and outpatient treatment.