Detection of phentermine in hair samples from drug suspects

Phentermine (PT) has been widely used as an anti-obesity drug. This drug has to be used with caution due to its close resemblance with amphetamines in its structure and toxicity profile. Recently, PT is in distribution by illegal modes and is found to be available through sources such as the internet, thus their misuse and/or abuse is threatening to be a serious social issue. In the present study, 32 cases of drug suspects were observed for PT abuse, detected using hair samples for drug analysis. PT and other amphetamines, such as methamphetamine (MA), amphetamine (AP), 3,4-methylenedioxyamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA), were extracted using 1% HCl in methanol for 20 h at 38°C. The extracts were derivatized with trifluoroacetic anhydride (TFAA) and analyzed using gas chromatography/mass spectrometry (GC/MS). Among the 32 cases of PT abuse, MA and its main metabolite, AP were identified in seven cases and MDMA and its main metabolite, MDA were detected in two other cases.     

Pushing the Envelope for Representation and Participation: the case of homeowner activism in Beijing

This article discusses the evolution of urban homeowner activism in two senses: internally (growth through internal diversity) and externally (advancement in interaction with the state). The combination of these two aspects has directed the activism toward the expansion of its boundaries, as well as advanced representation and participation. Based on cumulative fieldwork carried out since 2007, I discuss two homeowner organizations in Beijing as core cases. Rights activism by homeowners has grown beyond the state-set boundaries of individual neighborhoods and has begun deploying innovative strategies and adapting existing institutions for its own use. Rights awareness and manifestation by social actors has evolved continuously. This evolution suggests the emergence of a complex interplay between state and society which goes beyond a confrontational or lopsided relationship.     

On statistical analysis of forensic DNA: theory, methods and computer programs

Statistics plays an important role in evaluating the evidential weight of forensic DNA. In this paper, general statistical principles for forensic DNA analysis are presented. We introduce the theory and methods for the statistical assessment in kinship determination and DNA mixture evaluation. In particular, analytical formulas for testing for biological relationship among three individuals and for assessing the DNA mixture evidence in the case of multiple subdivided ethnic groups are developed. Two user-friendly computer programs are demonstrated to exhibit their wide applicability in tackling with complex kinship/paternity and mixture problems. The EasyDNA program can solve a complicated paternity case in 1 min.     

Simultaneous analysis of d-3-methoxy-17-methylmorphinan and l-3-methoxy-17-methylmorphinan by high pressure liquid chromatography equipped with PDA

d-3-Methoxy-17-methylmorphinan (Dextromethorphan, DXM), which is a structural analog of morphine and codeine, has been widely used as a non-narcotic antitussive agent. It is a safe drug in therapeutic dose and does not produce analgesic effects, while its enantiomer, l-3-methoxy-17-methylmorphinan called levomethorphan (LXM) is a potent narcotic analgesic. DXM has been widely abused in Korea due to its hallucinogenic effect in large doses; therefore, the health authorities have regulated its use as a psychotropic agent since 2003. As its abuse has been serious, a possibility that DXM would be smuggled into Korea has also increased. Moreover, it has been suspected that there was the possibility of the adulteration or substitution of DXM with LXM due to their chemical similarities. Therefore, it was necessary for us to establish the enantiomeric separation of DXM and LXM. In this study, a liquid chromatographic method using a chiral column capable of separating stereoisomers of DXM as well as analyzing the major metabolites of DXM, 3-methoxymorphinan, 3-hydroxymorphinan, and 17-hydroxymethylmorphinan was developed. The validation of a method was studied through repeatability of retention times. Using this method, 32 confiscated DXM samples were analyzed to identify the enantiomers of DXM. As a result, DXM was detected in all samples and there was no evidence of the adulteration or substitution of DXM with LXM. Nevertheless, the stereochemical analysis of DXM and LXM is important not only to identify starting materials for illegal drug manufacture but also to understand the trends of abused drugs.     

Problems and profitability of direct foreign investiment in China: An analysis of the survey data

By analyzing a survey in the Tianjin area, this article investigates the problems and profitability of joint ventures in China, and draws some policy implications. The authors find that there are a number of systemic constraints on the profitability of joint ventures, such as input and foreign exchange shortages, rigid labor policies, conflicts between business partners, and uneasy relations with state authorities. The article concludes that unless the investment environment is improved, China will not succeed in the competition with other developing countries in attracting the foreign capital needed for its modernization. Chung H. Lee is a professor of economics at the University of Hawaii at Manoa and research associate at the Institute for Economic Development and Policy of the East-West Center. He is also author ofThe Economic Development in Japan and Korea (Praeger 1990) andTrade and Investment in Services (Westview 1988).     

A comparative study on legal frameworks of work and family reconciliation in Mozambique and Tanzania

ABSTRACT

This paper analyses legal frameworks designed to reconcile work and family responsibilities in Mozambique and Tanzania from the perspective of ILO standards. Three labour laws are explored, the Mozambique Family Law 2004, the Mozambique Labour Law 2007, and the Tanzania Employment and Labour Relations Act 2004. ILO standards have encouraged both countries to become better equipped for working families to reconcile their work and family responsibilities. Their legal frameworks, however, remain below ILO standards, especially in parental leave and childcare services. The paper finds the root cause of such low compliance from a number of historical junctures, including a historical hangover from colonial regimes, social development policies and structural adjustment policies. The paper suggests a stronger commitment by the Mozambique and Tanzania governments’ and active involvement of civil societies to reshape the patriarchal political economy and promote gender equality in both public and private spheres.     

Effects of Public Service Motivation on Turnover and Job Satisfaction in the U.S. Teacher Labor Market

A substantial body of research has addressed the importance of the match between the person and the organization, or jobs for individuals and organizational outcomes across diverse fields. Despite growing attention to the role of the person–environment (P–E) fit, there are few studies incorporating the characteristics of jobs in the relationship between public service motivation (PSM) and job satisfaction. Drawing on the growing literature concerning PSM and teacher recruitment and retention, this study investigates whether altruistic work values, such as a strong altruistic desire and a preference for correcting social inequity, affect job satisfaction and teacher turnover.     

Economic interest or security concerns? Which affected how individuals in five Asian countries—Indonesia,Japan, Malaysia,the Philippines,and South Korea—viewed China in 2013?

With rapid economic growth, China has become its neighbours’ largest trade partner in the twenty-first century. At the same time, the growth of China’s military and its assertiveness are raising concerns among its neighbours that China’s rise will pose a threat to them. In this context, will China’s neighbours—Indonesia, Japan, Malaysia, the Philippines, and South Korea—view China positively or negatively? By using statistical analysis, this paper aims to explore whether individuals are more affected by their economic position or national security concerns when they view China. The findings in this article suggest that individuals’ security concerns have stronger associations with their attitudes toward China than economic conditions. Specifically, individuals’ views on China’s military growth and territorial disputes had negative effects on their attitudes toward China. On the other hand, economic interests had weaker associations with individuals’ views of China than security concerns.