C6-polymorphism of the sixth component of complement: application to paternity cases (author's transl)]

The results of a study of the polymorphism of the sixth component of human complement by means of isoelectric focusing in polyacrylamide gels with subsequent C-dependent lysis in an agarose overlay containing C6 deficient rabbit serum are reported. The allele frequencies obtained (C6A = 0.613, C6B = 0.379, C6R = 0.008) are in good agreement with those previously published. The mode of inheritance in 47 families with 173 offspring as well as 26 mother-child combinations is in agreement with a formal genetical model: "C6A, C6B, C6A1 and C6B1 at an autosomal locus". The inclusion of this system into a blood group expertise in Germany can be recommended.     

The effect of ethanol and antabus-antabus-alcohol-reaction on histamin and mast cell. Contents of the lung (author's transl)]

Alcohol--orally given in concentrations from 1 to 4 g/kg body-weight--leads to a reduction of mast cells in the guinea pig lung. At the same time a minor decrease of histamine concentration was observed. The incompatibility reaction with alcohol after disulfiram intake (DAR) shows an additional degranulation oft mast cells of the lungs and decrease of histamine-content. So far, there seems little difference between the influence of disulfiram alone and the DAR. Besides thrombocytes and basophile leucocytes, the mast cells of the lung are responsible for the release of histamine and serotonine during higher alcohol concentrations and alcohol-disulfiram-reactions. We think that the intolerance phenomena of humans after alcohol--f.e. in form of flush-reaction--is at least partly related to the concomitant influence oft mast cell-substances.     

Book reviews

A. L. Meiendorf, Optimizatsiya khozyaistvennykh reshenii: metod analiza prirashchenii. Series: Aktual'nye problemy sel'skogo khozyaistva. Moscow: ‘Ekonomika’, 1976.

Oliver H. Radkey, The Unknown Civil War in Soviet Russia. A Study of the Green Movement in the Tambov Region, 1920–21. Stanford, Calif.: Hoover Institution, 1976. xiv+457 pp. $12.95.

Roy and Zhores Medvedev, Khrushchev—The Years in Power. London: OUP, 1977. xi+198 pp. £3.95.

Daniel F. Calhoun, The United Front: the TUC and the Russians, 1923–1928. Cambridge: CUP, 1976. 450 pp. £10.50.

Gabriel Gorodetsky, The Precarious Truce. Anglo‐Soviet Relations 1924–27. Cambridge: CUP, 1977. 289 pp. £9.00.

Herbert S. Dinerstein, The Making of a Missile Crisis: October 1962. Baltimore and London: Johns Hopkins UP, 1976. 302 pp. $14.95.

Donald R. Kelley, Kenneth R. Stunkel, Richard R. Wescott, The Economic Superpowers and the Environment: The United States, The Soviet Union, and Japan. San Francisco: W. H. Freeman & Co., 1976. 335 pp.

Fred Singleton (ed.), Environmental Misuse in the Soviet Union. New York and London: Praeger Publishers, 1976. xvii+103 pp. $13.50. £8.80.

Peter H. Juviler, Revolutionary Law and Order. Politics and Social Change in the USSR. New York: The Free Press, and London: Collier MacMillan, 1976. xii+274 pp. £11.05.

Richard Szawlowski, The System of the International Organizations of the Communist Countries. Leyden: A. W. Sijthoff, 1976. 322 pp.

Jürg Meister, Soviet Warships of the Second World War. London: Macdonald & Jane, 1977. 348 pp. £7.95.