Detection of deception with fMRI: Are we there yet?

A decade of spectacular progress in functional magnetic resonance imaging (fMRI) technology and systems neuroscience research has so far yielded few changes in our daily lives. The dearth of clinical applications of this prolific and academically promising research tool began raising the eyebrows of the public and the research funding agencies. This may be one of the reasons for the enthusiasm and interest paid to the growing body of literature suggesting that blood oxygenation level‐dependent (BOLD) fMRI of the brain could be sensitive to the differences between lie and truth. The word ‘differences’ is critical here since it refers to the often‐ignored core concept of BOLD fMRI: it is only sensitive to differences between two brain states. Thus, available studies report using fMRI to discriminate between lie and truth or some other comparative state rather than to positively identify deception. This nuance is an example of the extent to which applied neuroscience research does not lend itself to the type of over‐simplification that has plagued the interpretation of fMRI‐based lie detection by the popular press and the increasingly vocal academic critics. As an early contributor to the modest stream of data on fMRI‐based lie detection, I was asked by Dr Aldert Vrij to write a piece in favour of fMRI‐based lie detection, to be contrasted with a piece by Dr Sean Spence presenting an opposite point of view ( Spence, 2008 ). This seemingly straightforward task presented two hurdles: having to respond to the popular as well as scientific view of what lie detection with fMRI is and present a wholly positive view of evolving experimental data.     

Student Success and Failure in a Graduate Criminology/Criminal Justice Program

Despite the burdens that students and institutions assume when underwriting educational careers, very little is known about completion rates, risk factors, and successful strategies of criminology/criminal justice (CCJ) graduate programs. Consequently, the present study tracks 287 master’s and 70 doctoral students who entered the Florida State University CCJ program during the 1991–2000 academic years. Almost two-thirds of this cohort earned an advanced degree. Younger students with higher GRE scores were more likely to complete the master’s program. Successful doctoral degree recipients tended to have lower GRE scores, be non-White, and earn their master’s degrees in-house. In terms of time-to-degree, it took over two years to earn an M.A. and slightly more than six years to negotiate the Ph.D. Implications are explored for the program, the university, and the discipline.     

Post-injection hybridization of complementary DNA strands on capillary electrophoresis platforms: A novel solution for dsDNA artifacts

Several laboratories have reported the occurrence of a split or n − 1 peak at the vWA locus in PowerPlex^® 16 and PowerPlex^® ES amplification products separated on 4- and 16-capillary electrophoresis instruments. The root cause of this artifact is post-PCR reannealing of the unlabeled, unincorporated vWA primer to the 3′-end of the tetramethylrhodamine (TMR)-labeled strand of the vWA amplicon. This reannealing occurs in the capillary post-electrokinetic injection. The split peak is eliminated by incorporation into the loading cocktail of a sacrificial hybridization sequence (SHS) oligonucleotide that is complementary to the vWA primer. The SHS preferentially anneals to the primer instead of the TMR-labeled strand of the vWA amplicon. In addition, the n − 10/n − 18 artifact that may be seen at the vWA locus was determined to be due to double-stranded amplicon formed post-electrokinetic injection into the capillary. This was also eliminated by adding in two Complementary Oligo Targets (COT1 and COT2) in addition to the SHS oligonucleotide into the loading cocktail. These three oligonucleotides are complementary to the 33 bases at the 5′-end of the unlabeled vWA amplicon strand and the 60 bases at its 3′-end and therefore compete for hybridization to the TMR-labeled amplicon strand. Incorporation of these three oligonucleotides in the Internal Lane Standard 600 (ILS600) eliminate both the split peak and n − 10/n − 18 artifact in PowerPlex^® 16 and PowerPlex^® ES amplification products without affecting sizing of alleles at the vWA locus or any locus in the PowerPlex^® 16, PowerPlex^® Y, PowerPlex^® ES, AmpFlSTR^® Profiler Plus^® ID, AmpFlSTR^® Cofiler^®, and AmpFlSTR^® SGM Plus^® kits.     

Naturschutzrechtliche Vorgaben zur Verwendung gebietseigener Gehölze

Zusammenfassung  Die genetische Vielfalt ist oft übersehenes Schutzgut des Naturschutzrechts. Sie ist der Grund, warum zunehmend gefordert wird, Anpflanzungen nur mit gebietseigenem Pflanzmaterial durchzuführen. Rechtliche Probleme stellen sich hier an der Schnittstelle von Naturschutz- und Vergaberecht. Soll n?mlich bei der ?ffentlichen Auftragsvergabe zur Anpflanzung von Geh?lzen oder beim Einkauf von Pflanzmaterial nicht gegen vergaberechtliche Vorschriften versto?en werden, bedarf es hinreichender, im Naturschutzrecht verwurzelter Gründe, um ?ffentliche Ausschreibungen ausschlie?lich auf gebietseigenes Pflanzmaterial einzuengen. Diesen naturschutzrechtlichen Verpflichtungen geht der vorliegende Beitrag nach.     

Zum grundbücherlichen Richtigkeitsgebot und seiner amtswegigen Verwirklichung (§ 28 LiegTeilG) (1. Teil)

Die übereinstimmung zwischen Grundbuch, Kataster und Realit?t liegt im Schnittpunkt zwischen Gesetzgebung und ?konomie im ?ffentlichen Interesse. Im LiegTeilG, sohin an unvermuteter Stelle, ist ein Verfahren zur amtswegigen Verwirklichung dieses Kongruenzprinzips normiert, dessen prozessuales Instrumentarium durch auch jüngste Gesetzgebungsakte direkt und indirekt deformiert worden ist. Diese Abhandlung untersucht, ob die ursprünglich verfolgten gesetzgeberischen Intentionen zur Herstellung der Grundbuchsordnung auf der geltenden Rechtslage im judikativen Weg gem §§ 6 f ABGB revitalisierbar sind oder ob es zu deren Reanimation eines legistischen Eingriffs bedarf.