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141.
Wyman JF Dean DE Yinger R Simmons A Brobst D Bissell M Silveira F Kelly N Shott R Ohr J Howard R Lewis B 《Journal of forensic sciences》2011,56(3):694-699
Drug levels in decomposed individuals are difficult to interpret. Concentrations of 16 drugs were monitored in tissues (blood, brain, liver, kidney, muscle, and soil) from decomposing pigs for 1 week. Pigs were divided into groups (n = 5) with each group receiving four drugs. Drug cocktails were prepared from pharmaceutical formulations. Intracardiac pentobarbital sacrifice was 4 h after dosing, with tissue collection at 4, 24, 48, 96, and 168 h postdosing. Samples were frozen until assay. Detection and quantitation of drugs were through solid phase extraction followed by gas chromatograph/mass spectrometer analysis. Brain and kidneys were not available after 48 h; liver and muscle persisted for 1 week. Concentration of drugs increased during decomposition. During 1 week of decomposition, muscle showed average levels increasing but concentrations in liver were increased many fold, compared to muscle. Attempting to interpret drug levels in decomposed bodies may lead to incorrect conclusions about cause and manner of death. 相似文献
142.
Rick Anderson 《Journal of Public Affairs (14723891)》2023,23(4):e2875
This contribution concerns a study that aims to trace factors that determine the effectiveness of policy implementation. To this end, a case study was conducted in two municipalities. In both municipalities, a random sample was drawn of 100 activities in the cultural field carried out in the year 2021. Based on this, the effectiveness of the implementation of subsidy provision was examined for both municipalities. This effectiveness has been operationalised to the percentage of correct non-applications, the percentage of rightly approved subsidy applications and the percentage of rightly rejected subsidy applications. A comparison between these municipalities, based on an analysis of the documents and 22 interviews, then provided an opportunity to explain differences in effectiveness. It turns out, that the control function provides the decisive explanation for the difference in effectiveness. This control function is not only about monitoring and controlling the implementation, but also about facilitating and optimising the process of providing subsidies. Although previous research highlights the importance of an adequate monitoring and control for implementation, the control function can be defined in a broader way. Besides overseeing proper implementation, the control function in this broader view also plays a facilitating role towards the implementers. This broader control function specifically has not often been the explicit object of implementation research. It should be noted, however, that this study is based on only two municipalities, which only examined the subsidisation of cultural activities. Therefore, no general conclusions can be drawn on this basis. 相似文献