Elevated and similar urinary testosterone/epitestosterone ratio in all samples of a competition testing: suspicion of a manipulation

The case of seven urine samples collected for anti-doping purposes during a cycling stage race with moderately elevated testosterone and epitestosterone ratio (T/E) is reported. The very low probability of having all seven urine samples with such similar elevated T/E ratio (from 3.2 to 4.7) was very suspicious. Different pattern classification tools were tested to categorize the most similar steroid profiles, but none of the models enabled a clear classification of the different urine samples. Subsequently, genetic profiling of all urine samples was performed and demonstrated that three of the seven samples were collected from the same cyclist. Finally, the International Federation confirmed DNA profiling results. This suggests that urinary steroid data using several methodologies are not appropriate for identification purposes and to an extent not unique to individuals.     

A systematic analysis of diversion: Net widening and beyond

This analysis focuses on the operation of a juvenile diversion program in a large metropolitan area. In particular, the impact of the program on referrals made by the police to the juvenile court is examined. Consistent with most studies of diversion, a significant amount of net widening was found to occur following the introduction of the program. A time-series design using a four-year-preprogram and four-year-program period was employed to examine the trends in processing over time. Referrals for all categories of offenses rose significantly during the program years. The implications of these results are discussed in light of both police commitment to the goals of diversion and the legal safeguards in juvenile processing.     

A fatal poisoning with LSD

Radioimmunoassay, high-performance liquid chromatography and capillary gas chromatography-mass spectrometry were used to detect and measure LSD in the first reported case of fatal poisoning by LSD. The levels found in ante-mortem serum and plasma and in post-mortem blood, liver blood and stomach contents are given.     

The Massachusetts Task Force on Secure Facilities: An Examination of the Issue of Security in a Community-Based System of Juvenile Corrections

Authors' note: This article reviews the findings of the Massachusetts Task Force on Secure Facilities' Final Report “The Issue of Security in a Community-Based System of Juvenile Corrections,” L. Scott Harshbarger, Chairman (1977), and includes the comments of the authors which do not necessarily represent the official position of the Task Force.