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This article reviews maltreatment-related pediatric posttraumatic stress disorder (PTSD) neuroimaging and neuropsychology research. Existent interventions that target brain networks associated with PTSD and cognitive impairment are highlighted. Furthermore, the benefits of combining neuroimaging and neuropsychology research in treatment outcomes are discussed. To conduct this review, a literature search was done utilizing the words MRI, structural, functional, neuropsychological testing, children, maltreatment, treatment, and PTSD. This was supplemented with a direct search of developmental trauma experts. Results from the neuroimaging studies found differences in the total cerebral volume, prefrontal cortex, hippocampus, cerebellum, superior temporal gyrus, corpus callosum, and other regions in maltreatment-related childhood PTSD. Neuropsychological findings demonstrate deficits in memory, attention, learning, and executive function that correspond to these brain regions. Existent and novel psychotherapeutic interventions address these deficits. These interventions may be directed at key networks associated with cognitive processing. Future directions include the implementation of treatment outcome research integrating psychotherapy with putative biological and psychological markers. 相似文献
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All cases of fatal oxycodone toxicity presenting to the New South Wales Department of Forensic Medicine over the period January 1, 1999, to December 31, 2008, were retrieved. A total of 70 cases were identified. The mean age was 48.9 years, 58.6% were men, 21.4% were suicides, and in 30% oxycodone had not been prescribed to the decedent. Injecting drug users constituted 27.1% of cases, and oxycodone tablets were injected immediately prior to death by 21.4%. The mean blood oxycodone concentration was 0.40 mg/L (range 0.06-53.00 mg/L). In all cases, psychoactive substances other than oxycodone were also detected, most frequently hypnosedatives (68.6%), other opioids (54.3%), antidepressants (41.4%), and alcohol (32.9%). Preexisting systemic disease was common: cardiovascular (64.2%), pulmonary (49.3%), hepatic (66.7%), and renal (43.9%). 相似文献
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In a recent contribution to Political Behavior (30:455–467), Panagopoulos, using aggregate turnout data, shows that individuals living under compulsory voting rules are
most likely to go to the polls when penalties for abstaining are both strict and routinely enforced. In this project, I expand
on the work of Panagopoulos by simultaneously examining both election-level and individual-level factors. I use a broad sample
of 36 countries, some with compulsory voting and some with voluntary rules, which provides a more detailed understanding of
the correlates of turnout. Results indicate that the presence and severity of compulsory rules do indeed affect turnout, while
personally held characteristics, including age, education, income, and political efficacy remain critical to an individual’s
turnout decision calculus. 相似文献
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Kate J. Bowers Shane D. Johnson Rob T. Guerette Lucia Summers Suzanne Poynton 《Journal of Experimental Criminology》2011,7(4):347-374