Definitions of suicidal behavior: lessons learned from the WHo/EURO multicentre Study

Based on the experience matured during the 15 years of the WHO/EURO Multicentre Study on Suicidal Behavior, this paper provides an excursus on main elements that characterize components for definitional needs. It describes the rationale for choosing the initial set of definitions within the study and the subsequent problems and developments. As a result, unifying terminologies are proposed.     

Acute flurazepam intoxication: a case report

A fatality due to ingestion of flurazepam is reported. Flurazepam is a benzodiazepine, a widely prescribed hypnotic drug for use in sleep disorders. There are only few documented reports of the disposition of flurazepam in deaths due to overdose. A 68-year-old woman was found deceased at home with no evidence of trauma or asphyxia. Toxicologic analyses were performed and drug levels measured by means of gas chromatography coupled to mass spectrometry. The flurazepam concentration in each specimen was as follows: heart blood 2.8 microg/mL, bile 323 microg/mL, and urine 172 microg/mL. Presence of flurazepam into gastric content was observed too. Based on the autopsy findings, patient history, and toxicologic results, the cause of death was determined to be acute intoxication of flurazepam and the manner, suicide.     

Medicolegal aspects of an unusual uterine perforation with multiload-Cu 375R

Perforation of the uterus is one of the most serious complications associated with insertion of intrauterine contraceptive devices (IUD). According to recent studies, this lesion occurs in 0.87 per 1000 cases, but statistics generally fluctuate between 0.05 and 13 per 1000 insertions. "Primary" perforations occur at the time of IUD insertion, and "secondary," or delayed, perforations are usually assumed to be caused by reactive uterine contractions. We report an unusual case of uterine perforation, which occurred 9 days after the insertion of a Multiload-Cu 375 IUD. The criteria for differential diagnosis between primary and secondary complications are discussed, particularly from the perspective of medical malpractice cases.     

Reference ballistic imaging database performance

Ballistic imaging databases allow law enforcement to link recovered cartridge cases to other crime scenes and to firearms. The success of these databases has led many to propose that all firearms in circulation be entered into a reference ballistic image database (RBID). To assess the performance of an RBID, we fired 4200 cartridge cases from 600 9mm Para Sig Sauer model P226 series pistols. Each pistol fired two Remington cartridges, one of which was imaged in the RBID, and five additional cartridges, consisting of Federal, Speer, Winchester, Wolf, and CCI brands. Randomly selected samples from the second series of Remington cartridge cases and from the five additional brands were then correlated against the RBID. Of the 32 cartridges of the same make correlated against the RBID, 72% ranked in the top 10 positions. Likewise, of the 160 cartridges of the five different brands correlated against the database, 21% ranked in the top 10 positions. Generally, the ranking position increased as the size of the RBID increased. We obtained similar results when we expanded the RBID to include firearms with the same class characteristics for breech face marks, firing pin impressions, and extractor marks. The results of our six queries against the RBID indicate that a reference ballistics image database of new guns is currently fraught with too many difficulties to be an effective and efficient law enforcement tool.     

Globalization and Fiscal Federalism: Does Openness Constrain Subnational Budget Imbalances?

Recent research has shown that more globalized countries—defined as those with stronger international trade and financial linkages—tend to have larger governments. The empirical evidence reported in this paper shows that globalization is also associated with the government's fiscal stance, nationally and subnationally. Greater access to external sources of finance, which can be facilitated through globalization, is associated with increased market scrutiny over policies, resulting in a higher premium on fiscal discipline.     

A tale of two policies: The politics of climate forecasting and drought relief in Ceará, Brazil

This paper evaluates the use of climate-based information in drought mitigation in Ceará, Northeast Brazil. It examines two policies – a seed-distribution program (Hora de Plantar) and the Emergency Drought-Relief Program – that use climate information produced by FUNCEME (Cearás Foundation for Meteorological and Hydrological Resources) to implement drought planning. It argues that, in politically charged policy-making environments, the use of climate forecast information may go beyond its problem-solving function to influence broader issues of accountability and democratization. In Cearás politically charged environment, technocrats rely on scientific information about climate to insulate policy-making from both political meddling and public accountability. However, insulation afforded by the use of climate information has played different roles in the policy areas examined in this study. While in drought emergency-relief planning the use of climate information critically contributed to the democratization of policy implementation, in agricultural planning, it worked towards further insulating decision-making from public accountability and client participation. Thus, the use of climate information is context-dependent, that is, the distribution of costs and benefits associated with information use in policymaking depends on the social, political, and cultural context in which information producers and users work. Moreover, climate information can be used in ways – positive or negative – significantly different from the use that information producers intended.     

Identification of two fire victims by comparative nuclear DNA typing of skeletal remains and stored umbilical tissues

We describe here our collaborative efforts in identifying 2 fatalities of a fire disaster by using a variety of identification techniques. Postmortem findings in both cases were reinforced using Short Tandem Repeat (STR) DNA technology to establish with a high degree of certainty the identities of 2 child victims. STR markers used in the present study include HUMAMEL, HUMCSFIPO, HUMTHO1, HUMvWA, HUMFES/FPS, HUMF13A01, HUMFOLP23, D8S3O6, HUMFGA, and HUMTPOX. Unambiguous identification was made possible through matching DNA profiles generated from skeletal remains with those from umbilical tissues. These tissues were kept by their mothers in accordance with a Philippine tradition and were submitted for DNA analysis. Of the DNA profiles generated from exhumed bone samples of 21 child victims, comparison with the genetic profiles of children A and B obtained from umbilical tissues showed consistent DNA matches with remains 1756 and 1758, respectively.     

Allele sharing in first-degree and unrelated pairs of individuals in the Ge F I AmpFlSTR Profiler Plus database

Eleven Italian forensic laboratories participated in a population study based on the AB Profiler Plus loci with proficiency testing. The validated database, including 1340 individuals, is available on-line. Tests for Hardy-Weinberg equilibrium, gametic unbalance, and heterogeneity of gene frequency were generally not significant. Gene frequencies at each locus were consistent with those of two previously published Italian studies, but different from a third. Individuals of each subsample were paired, and the total number of alleles shared across the nine loci was determined in each pair. The analysis was replicated over the total sample. In addition, two samples of mother-child pairs (N=315) and full-sib pairs (N=91) were subjected to allele sharing analysis. The resulting distributions were sufficiently distinct from the sample of unrelated pairs as to be of practical usefulness.     

The university and the human sciences

The current malaise affecting the university in general and the human sciences in particular has a deeper origin than is usually recognized. It has to do with the gap between science and culture, between the scientific way of dealing with things and the ordinary-lifeway of dealing with them. The more the university is seen as the bastion of science, the less those sciences, which traditionally deal with human affairs as seen from the ordinary, common sense point of view, are taken seriously. It is particularly the Geisteswissenschaften which are de facto depreciated. The usual reaction is an attempt to ever more professionalism and methodological rigidity also in these sciences. This leads to disastrous consequences both for the Geisteswissenschaften and for the university as a whole. This revised version was published online in July 2006 with corrections to the Cover Date.