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Phillips SA Lowe A Marshall M Hubbard P Burmeister SG Williams DR 《Journal of forensic sciences》2000,45(2):324-332
Recent criminal acts in the United Kingdom, United States and other countries have demonstrated the dangers to public safety from the criminal use of improvised explosives on a large scale. Four sets of trials were carried out over four years, partly in collaboration with the United States Federal Bureau of Investigation, involving the firing of large bombs, mostly fertilizer based. The principal objectives of the firings were to measure the physical effects of the explosions upon objects representative of those that would be found at a real bomb scene and to recover any chemical traces deposited on these objects. The results are intended for use as an aid in determining the approximate size and type of an explosive employed in a terrorist attack. This paper describes the background behind the trials, the procedures for preparation of witness materials and charges, and the collection and analysis of physical and chemical evidence. 相似文献
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In recent years, walkway slip-resistance testing with grooved NTL (Neolite Test Liners) has been the subject of research, as well as used in field investigation practices. Recent research shows that differences between non-grooved and grooved test feet do exist, especially under wet conditions. It is not known how the number of grooves influences the slip resistance. This study investigates the influence of groove count on slip resistance under both wet and dry conditions using the PIAST tribometer. Test feet with 1, 3, 5, 7, 9, 11, 13, and 15 grooves and a non-grooved test foot were used. Polished granite and vinyl composition tile were used as test surfaces. Results for both test surfaces show markedly higher slip resistance for increasing groove counts under wet conditions, while under dry conditions, the results show slight increases in slip resistance. Implications of these results are discussed. 相似文献
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Bill M Gill P Curran J Clayton T Pinchin R Healy M Buckleton J 《Forensic science international》2005,148(2-3):181-189
Several years ago, a theory to interpret mixed DNA profiles was proposed that included a consideration of peak area using the method of least squares. This method of mixture interpretation has not been widely adopted because of the complexity of the associated calculations. Most reporting officers (RO) employ an experience and judgement based approach to the interpretation of mixed DNA profiles. Here we present an approach that has formalised the thinking behind this experience and judgement. This has been written into a computer program package called PENDULUM. The program uses a least squares method to estimate the pre-amplification mixture proportion for two potential contributors. It then calculates the heterozygous balance for all of the potential sets of genotypes. A list of "possible" genotypes is generated using a set of heuristic rules. External to the programme the candidate genotypes may then be used to formulate likelihood ratios (LR) that are based on alternative casework propositions. The system does not represent a black box approach; rather it has been integrated into the method currently used by the reporting officers at the Forensic Science Service (FSS). The time saved in automating routine calculations associated with mixtures analysis is significant. In addition, the computer program assists in unifying reporting processes, thereby improving the consistency of reporting. 相似文献
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Since 1995 the Forensic Science Service (FSS) has carried out DNA profiling of reference samples for the UK National DNA Database and in forensic casework using two multiplex STR profiling systems. During this period, profiles with anomalous banding patterns, although comparatively rare, have been encountered regularly. The FSS has collected instances of triallelic patterns and aberrant diallelic patterns. A systematic examination of these patterns has provided insight into their underlying genetic cause. The triallelic patterns could be classified into two types based on the relative intensities of their component alleles. In the Type 1 pattern the alleles were of uneven intensity, whereas in the Type 2 pattern, all three alleles were of even intensity. Evidence is presented that the more frequent Type 1 pattern is the result of somatic mutation at a heterozygous locus, and the Type 2 pattern is the result of a localized chromosomal rearrangement at a heterozygous locus. Directly from the Type 1 pattern, it was possible to deduce the size difference between the progenitor and mutated allele. All mutational changes were found to be multiples of four nucleotides, suggesting the loss or addition of one or more tetrameric repeat units. Aberrant diallelic patterns were identified by analysts due to an unexpectedly large difference in intensity between alleles at a heterozygous locus. While some of these diallelic patterns are likely caused by the same genetic phenomena described above occurring at a homozygous locus, others are demonstrated to be caused by a mutation in the primer binding sequence, leading to a reduction in amplification efficiency of one allele. It is concluded that based on a visual inspection of a profile, it is possible to infer a likely genetic basis directly from the triallelic pattern. By contrast, the aberrant diallelic patterns can be due to any one of a number of possible genetic effects. 相似文献
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This article explores some of the intellectual influences which have shaped the development of Critical Legal Studies in Britain
and the contexts in which these influences made themselves felt. It then considers which influences might or should steer
Critical Legal Studies in the future. In terms of the past, specific attention is given to the influence of Marxism, Freud
and Lacan, feminism, Foucault and Derrida, and recent genres of history-writing. As to the future, the question is asked whether
Critical Legal Studies will engage constructively with recent developments in the life sciences and the philosophy of science,
and, more generally, whether it will be able to surpass its established mooring in the philosophy of history.
This revised version was published online in July 2006 with corrections to the Cover Date. 相似文献