THC content of cannabis and cannabis resin in samples seized by the Swedish police

The THC-content in 1100 samples of cannabis resin and 600 of marihuana has been determined. The content of THC varied much, in the resin groups mostly depending on the origin and age of the resin and in the marihuana groups depending on the origin and race of the seeds.     

Quantification of mitochondrial DNA in human blood cells using an automated detection system

The 4977 bp deletion of mitochondrial DNA (mtDNA) accumulates in postmitotic tissues with advancing age. The purpose of our study was to detect and quantify these deletion even in blood cells with a high turnover activity. Whole venous blood, isolated human platelets and peripheral blood mononuclear cells (PBMCs) were collected from 10 unrelated donors aged 20-71 years and total DNA was extracted. PCR was performed for total and mutated mtDNA using two different primer pairs and two fluorogenic probes labeled with the fluorescent dyes FAM and VIC. Specific PCR products were generated, detected and quantified in a real-time PCR. The amplification products of total and deleted mtDNA could be detected in each sample and did not exhibit any differences in the amount of the deleted mtDNA in whole blood, human platelets or PBMCs. Our data did not show any accumulation of the 4977 bp deletion with increasing age as it was observed for several other tissues.     

The changing character of national borders

At the end of the twentieth century, the pace of change in the international system is increasing. New actors and even new categories of actors are emerging. Some have a strong impact on international relations, thus competing with the traditional type of international actor, the sovereign nation‐state. One salient feature of the nation‐state is its power to control its borders. In the process of globalization, this power is being disintegrated.

In some respects, national borders have completely lost their relevance, owing to certain adverse ecological developments like the degradation of the ozone layer and other virtually global threats. They are equally of limited use in influencing the speed and content of some trade operations concerning goods or currencies or the free flow of media information.

They however continue to function in a rather efficient way for people. Immigration laws and certain other procedures of the ‘rich’ countries tend to distinguish between wanted and unwanted immigrants. Due to various catastrophies and disasters, wide‐spread violence and the anticipation of a bleak economic future, the number of migrants continues to grow rapidly, as does the pressure from migrants from the ‘poor’ and densely populated countries of the world on the borders of the ‘rich’ countries. This is a multi‐dimensional development with political, economic, but also moral aspects.     

Misappropriation of Institutions: Some Lessons from the Environmental Dimension of the NAFTA Investor-State Dispute Settlement Process

Trade regimes at all levels have confronted the dual challenge of rapidly expanding foreign direct investment, and the vigorous growth of international environmental regimes. Attempts to develop a global investment regime have encountered resistance, not least from environmental interests. At the same time, regional trade regimes have sought to address both the environmental and the investment agenda but in a very different manner. This article looks at problems encountered with the investor-state dispute settlement process established by the North American Free Trade Agreement (NAFTA). The institutional dimension of this process is largely drawn from the General Agreement on Tariffs and Trade (GATT), and existing international institutions for commercial arbitration. The article traces some of the difficulties encountered in attempting to use institutions designed for a specific purpose and implemented in one organizational context, to achieve a different purpose in another organizational context. It discusses the problems that arise when institutions appropriate for settling commercial disputes between private actors are used as the basis for balancing private interests and public goods, the environment in particular. It highlights the importance of a more developed understanding of the interplay between institutions and organizations at the international level so as to avoid undesired outcomes.     

The relevance of legitimation – a new framework for analysis

ABSTRACT

The legitimacy of political orders is an important reference point in political analysis, but the concept is difficult to operationalize and measure – particularly in those countries where legitimacy is critical, i.e. cases of political transformation, non-democratic rule and high state fragility. To be successful, legitimation (the process by which legitimacy is procured) has to fulfil two functions: relate demands for legitimation to government performance (the ‘demand cycle’), and relate legitimacy claims issued by the rulers to behavioural patterns of the ruled (the ‘supply cycle’). Looking at the recent academic debate, the article finds that empirical research has largely ignored the demand cycle, while attempts to explore the relationships underlying the supply cycle tend to suffer from misconceptions of basic terms. The article proposes a framework for empirical enquiry that addresses both shortcomings.